- Hyperglycemia Enhances IGF-I-Stimulated Src Activation via Increasing Nox4-Derived Reactive Oxygen Species in a PKC zeta-Dependent Manner in Vascular Smooth Muscle Cells
[作者：Xi, G; Shen, XC; Maile, LA; Wai, C; Gollahon, K; Clemmons, DR,期刊：Diabetes, 页码：104-113 , 文章类型： Article，,卷期：2012年61-1]
- IGF-I-stimulated sarcoma viral oncogene (Src) activation during hyperglycemia is required for propagating downstream signaling. The aim of the current study was to determine the mechanism by which hyperglycemia enhances ...
- Identification of BMP and Activin Membrane-Bound Inhibitor (BAMBI) as a Potent Negative Regulator of Adipogenesis and Modulator of Autocrine/Paracrine Adipogenic Factors
[作者：Luo, X; Hutley, LJ; Webster, JA; Kim, YH; Liu, DF; Newell, FS; Widberg, CH; Bachmann, A; Turner, N; Schmitz-Peiffer, C; Prins, JB; Yang, GS; Whitehead, JP,期刊：Diabetes, 页码：124-136 , 文章类型： Article，,卷期：2012年61-1]
- Adipose tissue dysfunction underpins the association of obesity with type 2 diabetes. Adipogenesis is required for the maintenance of adipose tissue function. It involves the commitment and subsequent differentiation of ...
- Inotuzumab Ozogamicin Murine Analog Mediated B-Cell Depletion Reduces Anti-islet ABo- and Autoimmune Responses
[作者：Carvello, M; Petrelli, A; Vergani, A; Lee, KM; Tezza, S; Chin, M; Orsenigo, E; Staudacher, C; Secchi, A; Dunussi-Joannopoulos, K; Sayegh, MH; Markmann, JF; Fiorina, P,期刊：Diabetes, 页码：155-165 , 文章类型： Article，,卷期：2012年61-1]
- B cells participate in the priming of the allo- and autoimmune responses, and their depletion can thus be advantageous for islet transplantation. Herein, we provide an extensive study of the effect of B-cell depletion in...
- Cellular Mechanisms of Restored a-Cell Tolerance Mediated by Protective Alleles of Idd3 and Idd5
[作者：Hamilton-Williams, EE; Cheung, J; Rainbow, DB; Hunter, KM; Wicker, LS; Sherman, LA,期刊：Diabetes, 页码：166-174 , 文章类型： Article，,卷期：2012年61-1]
- Type 1 diabetes genes within the interleulcin (IL)-2, cytotoxic T-lymphocyte associated protein 4 (CTLA-4), and natural resistance-associated macrophage protein (NRAMP1) pathways influence development of autoinunune diab...
- Maternal Serum Levels of 25-Hydroxy-Vitamin D During Pregnancy and Risk of Type 1 Diabetes in the Offspring
[作者：Sorensen, IM; Joner, G; Jenum, PA; Eskild, A; Torjesen, PA; Stene, LC,期刊：Diabetes, 页码：175-178 , 文章类型： Article，,卷期：2012年61-1]
- Previous studies indicate reduced risk of type 1 diabetes after intake of vitamin D supplements during pregnancy or early childhood. We aimed to test whether lower maternal serum concentrations of 25-hydroxy-vitamin D (2...
- Heparanase Is Essential for the Development of Diabetic Nephropathy in Mice
[作者：Gil, N; Goldberg, R; Neuman, T; Garsen, M; Zcharia, E; Rubinstein, AM; van Kuppevelt, T; Meirovitz, A; Pisano, C; Li, JP; van der Vlag, J; Vlodavsky, I; Elkin, M,期刊：Diabetes, 页码：208-216 , 文章类型： Article，,卷期：2012年61-1]
- Diabetic nephropathy (DN) is the major life-threatening complication of diabetes. Abnormal permselectivity of glomerular basement membrane (GBM) plays an important role in DN pathogenesis. Heparanase is the predominant e...
- Greater Impact of Melanocortin-4 Receptor Deficiency on Rates of Growth and Risk of Type 2 Diabetes During Childhood Compared With Adulthood in Pima Indians
[作者：Thearle, MS; Muller, YL; Hanson, RL; Mullins, M; AbdusSamad, M; Tran, J; Knowler, WC; Bogardus, C; Krakoff, J; Baier, LJ,期刊：Diabetes, 页码：250-257 , 文章类型： Article，,卷期：2012年61-1]
- Features of melanocortin-4 receptor (MC4R) deficiency have been observed to be more pronounced in childhood. Longitudinal data from a population-based study were used to separate the phenotypic effects of MC4R deficiency...
- Relative Expression of a Dominant Mutated ABCC8 Allele Determines the Clinical Manifestation of Congenital Hyperinsulinism
[作者：Shemer, R; Ziv, CA; Laiba, E; Zhou, Q; Gay, J; Tunovsky-Babaey, S; Shyng, SL; Glaser, B; Zangen, DH,期刊：Diabetes, 页码：258-263 , 文章类型： Article，,卷期：2012年61-1]
- Congenital hyperinsulinism (CHI) is most commonly caused by mutations in the beta-cell ATP-sensitive K(+) (KATp) channel genes. Severe CHI was diagnosed in a 1-day-old girl; the mother's cousin and sister had a similar p...
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