- The Polymorphisms of DNA G-Quadruplex Investigated by Docking Experiments with Telomestatin Enantiomers
[作者:Alcaro, S; Costa, G; Distinto, S; Moraca, F; Ortuso, F; Parrotta, L; Artese, A,期刊:Current Pharmaceutical Design, 页码:1873-1879 , 文章类型: Review,,卷期:2012年18-14]
- Human telomeres are comprised of d(TTAGGG) repeats involved in the formation of G-quadruplex DNA structures. Ligands stabilizing these G-quadruplex DNA structures are potential inhibitors of the cancer cell-associated en...
- State-of-the-Art Methodologies for the Discovery and Characterization of DNA G-Quadruplex Binders
[作者:Pagano, B; Cosconati, S; Gabelica, V; Petraccone, L; De Tito, S; Marinelli, L; La Pietra, V; di Leva, FS; Lauri, I; Trotta, R; Novellino, E; Giancola, C; Randazzo, A,期刊:Current Pharmaceutical Design, 页码:1880-1899 , 文章类型: Review,,卷期:2012年18-14]
- Nowadays, the molecular basis of interaction between low molecular weight compounds and biological macromolecules is the subject of numerous investigations aimed at the rational design of molecules with specific therapeu...
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