- The Pan-ErbB Negative Regulator Lrig1 Is an Intestinal Stem Cell Marker that Functions as a Tumor Suppressor
[作者：Powell, AE; Wang, Y; Li, YN; Poulin, EJ; Means, AL; Washington, MK; Higginbotham, JN; Juchheim, A; Prasad, N; Levy, SE; Guo, Y; Shyr, Y; Aronow, BJ; Haigis, KM; Franklin, JL; Coffey, RJ,期刊：Cell, 页码：146-158 , 文章类型： Article，,卷期：2012年149-1]
- Lineage mapping has identified both proliferative and quiescent intestinal stem cells, but the molecular circuitry controlling stem cell quiescence is incompletely understood. By lineage mapping, we show Lrig1, a pan-Erb...
- Synergistic, Context-Dependent, and Hierarchical Functions of Epithelial Components in Thymic Microenvironments
[作者：Calderon, L; Boehm, T,期刊：Cell, 页码：159-172 , 文章类型： Article，,卷期：2012年149-1]
- Specialized niche environments specify and maintain stem and progenitor cells, but little is known about the identities and functional interactions of niche components in vivo. Here, we describe a modular system for the ...
- Wnt Signaling Regulates Acetylcholine Receptor Translocation and Synaptic Plasticity in the Adult Nervous System
[作者：Jensen, M; Hoerndli, FJ; Brockie, PJ; Wang, R; Johnson, E; Maxfield, D; Francis, MM; Madsen, DM; Maricq, AV,期刊：Cell, 页码：173-187 , 文章类型： Article，,卷期：2012年149-1]
- The adult nervous system is plastic, allowing us to learn, remember, and forget. Experience-dependent plasticity occurs at synapses-the specialized points of contact between neurons where signaling occurs. However, the m...
- Young Dentate Granule Cells Mediate Pattern Separation, whereas Old Granule Cells Facilitate Pattern Completion
[作者：Nakashiba, T; Cushman, JD; Pelkey, KA; Renaudineau, S; Buhl, DL; McHugh, TJ; Barrera, VR; Chittajallu, R; Iwamoto, KS; McBain, CJ; Fanselow, MS; Tonegawa, S,期刊：Cell, 页码：188-201 , 文章类型： Article，,卷期：2012年149-1]
- Adult-born granule cells (GCs), a minor population of cells in the hippocampal dentate gyrus, are highly active during the first few weeks after functional integration into the neuronal network, distinguishing them from ...
- A Role for tRNA Modifications in Genome Structure and Codon Usage
[作者：Novoa, EM; Pavon-Eternod, M; Pan, T; de Pouplana, LR,期刊：Cell, 页码：202-213 , 文章类型： Article，,卷期：2012年149-1]
- Transfer RNA (tRNA) gene content is a differentiating feature of genomes that contributes to the efficiency of the translational apparatus, but the principles shaping tRNA gene copy number and codon composition are poorl...
- Histone Recognition and Large-Scale Structural Analysis of the Human Bromodomain Family
[作者：Filippakopoulos, P; Picaud, S; Mangos, M; Keates, T; Lambert, JP; Barsyte-Lovejoy, D; Felletar, I; Volkmer, R; Muller, S; Pawson, T; Gingras, AC; Arrowsmith, CH; Knapp, S,期刊：Cell, 页码：214-231 , 文章类型： Article，,卷期：2012年149-1]
- Bromodomains (BRDs) are protein interaction modules that specifically recognize epsilon-N-lysine acetylation motifs, a key event in the reading process of epigenetic marks. The 61 BRDs in the human genome cluster into ei...
- Proline Isomer-Specific Antibodies Reveal the Early Pathogenic Tau Conformation in Alzheimer's Disease
[作者：Nakamura, K; Greenwood, A; Binder, L; Bigio, EH; Denial, S; Nicholson, L; Zhou, XZ; Lu, KP,期刊：Cell, 页码：232-244 , 文章类型： Article，,卷期：2012年149-1]
- cis-trans isomerization of proteins phosphorylated by proline-directed kinases is proposed to control numerous signaling molecules and is implicated in the pathogenesis of Alzheimer's and other diseases. However, there i...
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