- Loss-of-function germline GATA2 mutations in patients with MDS/AML or MonoMAC syndrome and primary lymphedema reveal a key role for GATA2 in the lymphatic vasculature
[作者:Kazenwadel, J; Secker, GA; Liu, YJJ; Rosenfeld, JA; Wildin, RS; Cuellar-Rodriguez, J; Hsu, AP; Dyack, S; Fernandez, CV; Chong, CE; Babic, M; Bardy, PG; Shimamura, A; Zhang, MY; Walsh, T; Holland, SM; Hickstein, DD; Horwitz, MS; Hahn, CN; Scott, HS; Harvey, NL,期刊:Blood, 页码:1283-1291 , 文章类型: Article,,卷期:2012年119-5]
- Recent work has established that heterozygous germline GATA2 mutations predispose carriers to familial myelodysplastic syndrome (MDS)/acute myeloid leukemia (AML), "MonoMAC" syndrome, and DCML deficiency. Here, we descri...
- GSK-3 beta regulates cell growth, migration, and angiogenesis via Fbw7 and USP28-dependent degradation of HIF-1 alpha
[作者:Flugel, D; Gorlach, A; Kietzmann, T,期刊:Blood, 页码:1292-1301 , 文章类型: Article,,卷期:2012年119-5]
- The hypoxia-inducible transcription factor-1 alpha (HIF-1 alpha) is a major regulator of angiogenesis, carcinogenesis, and various processes by which cells adapt to hypoxic conditions. Therefore, the identification of cr...
- The recombinant lectin-like domain of thrombomodulin inhibits angiogenesis through interaction with Lewis Y antigen
[作者:Kuo, CH; Chen, PK; Chang, BI; Sung, MC; Shi, CS; Lee, JS; Chang, CF; Shi, GY; Wu, HL,期刊:Blood, 页码:1302-1313 , 文章类型: Article,,卷期:2012年119-5]
- Lewis YAg (LeY) is a cell-surface tetrasaccharide that participates in angiogenesis. Recently, we demonstrated that LeY is a specific ligand of the recombinant lectin-like domain of thrombomodulin (TM). However, the biol...
- Macrophages have no lineage history of Foxp3 expression
[作者:Put, S; Avau, A; Humblet-Baron, S; Schurgers, E; Liston, A; Matthys, P,期刊:Blood, 页码:1316-1318 , 文章类型: Letter,,卷期:2012年119-5]
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- Genetic defects in PRC2 components other than EZH2 are not common in myeloid malignancies
[作者:Kroeze, LI; Nikoloski, G; da Silva-Coelho, P; van Hoogen, P; Stevens-Linders, E; Kuiper, RP; Schnittger, S; Haferlach, T; Pahl, HL; van der Reijden, BA; Jansen, JH,期刊:Blood, 页码:1318-1319 , 文章类型: Letter,,卷期:2012年119-5]
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