个性化文献订阅>文章检索

文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共35条记录   Potent in vitro and in vivo activity of an Fc-engineered humanized anti-HM1.24 antibody against multiple myeloma via augmented effector function [作者：Tai, YT; Horton, HM; Kong, SY; Pong, E; Chen, H; Cemerski, S; Bernett, MJ; Nguyen, DHT; Karki, S; Chu, SY; Lazar, GA; Munshi, NC; Desjarlais, JR; Anderson, KC; Muchhal, US,期刊：Blood, 页码：2074-2082 , 文章类型： Article，,卷期：2012年119-9] HM1.24, an immunologic target for multiple myeloma (MM) cells, has not been effectively targeted with therapeutic monoclonal antibodies (mAbs). In this study, we investigated in vitro and in vivo anti-MM activities of Xm... T-cell immunity to Kaposi sarcoma-associated herpesvirus: recognition of primary effusion lymphoma by LANA-specific CD4(+) T cells [作者：Sabbah, S; Jagne, YJ; Zuo, JM; de Silva, T; Ahasan, MM; Brander, C; Rowland-Jones, S; Flanagan, KL; Hislop, AD,期刊：Blood, 页码：2083-2092 , 文章类型： Article，,卷期：2012年119-9] T-cell immunity is important for controlling Kaposi sarcoma-associated herpesvirus (KSHV) diseases such as the endothelial cell malignancy Kaposi sarcoma, or the B-cell malignancy, primary effusion lymphoma (PEL). Howeve... Comparative outcome of initial therapy for younger patients with mantle cell lymphoma: an analysis from the NCCN NHL Database [作者：LaCasce, AS; Vandergrift, JL; Rodriguez, MA; Abel, GA; Crosby, AL; Czuczman, MS; Nademanee, AP; Blayney, DW; Gordon, LI; Millenson, M; Vanderplas, A; Lepisto, EM; Zelenetz, AD; Niland, J; Friedberg, JW,期刊：Blood, 页码：2093-2099 , 文章类型： Article，,卷期：2012年119-9] Few randomized trials have compared therapies in mantle cell lymphoma (MCL), and the role of aggressive induction is unclear. The National Comprehensive Cancer Network (NCCN) Non-Hodgkin Lymphoma (NHL) Database, a prospe... Trisomies in multiple myeloma: impact on survival in patients with high-risk cytogenetics [作者：Kumar, S; Fonseca, R; Ketterling, RP; Dispenzieri, A; Lacy, MQ; Gertz, MA; Hayman, SR; Buadi, FK; Dingli, D; Knudson, RA; Greenberg, A; Russell, SJ; Zeldenrust, SR; Lust, JA; Kyle, RA; Bergsagel, L; Rajkumar, SV,期刊：Blood, 页码：2100-2105 , 文章类型： Article，,卷期：2012年119-9] Routine incorporation of FISH into multiple myeloma (MM) diagnostic testing has led to a better appreciation of the heterogeneity of genetic abnormalities associated with this disease. We studied a group of 484 patients ... The IGHV1-69/IGHJ3 recombinations of unmutated CLL are distinct from those of normal B cells [作者：Forconi, F; Potter, KN; Sozzi, E; Henderson, I; Cencini, E; Rossi, D; Bomben, R; Gattei, V; Gaidano, G; Packham, G; Stevenson, FK,期刊：Blood, 页码：2106-2109 , 文章类型： Article，,卷期：2012年119-9] IGHV1-69/51p1 is expressed by similar to 30% of unmutated chronic lymphocytic leukemia (U-CLL) and combines with selected IGHD and IGHJ genes generating stereotypes if HCDR3 amino acid homology is > 60%. We had previousl... MicroRNA-650 expression is influenced by immunoglobulin gene rearrangement and affects the biology of chronic lymphocytic leukemia [作者：Mraz, M; Dolezalova, D; Plevova, K; Kozubik, KS; Mayerova, V; Cerna, K; Musilova, K; Tichy, B; Pavlova, S; Borsky, M; Verner, J; Doubek, M; Brychtova, Y; Trbusek, M; Hampl, A; Mayer, J; Pospisilova, S,期刊：Blood, 页码：2110-2113 , 文章类型： Article，,卷期：2012年119-9] MicroRNAs (miRNAs) play a key role in chronic lymphocytic leukemia as well as in normal B cells. Notably, miRNA gene encoding miR-650 and its homologs overlap with several variable (V) subgenes coding for lambda immunogl... TP53 alterations in acute myeloid leukemia with complex karyotype correlate with specific copy number alterations, monosomal karyotype, and dismal outcome [作者：Ruckner, FG; Schlenk, RF; Bullinger, L; Kayser, S; Teleanu, V; Kett, H; Habdank, M; Kugler, CM; Holzmann, K; Gaidzik, VI; Paschka, P; Held, G; von Lilienfeld-Toal, M; Lubbert, M; Frohling, S; Zenz, T; Krauter, J; Schlegelberger, B; Ganser, A; Lichter, P; Dohner, K; Dohner, H,期刊：Blood, 页码：2114-2121 , 文章类型： Article，,卷期：2012年119-9] To assess the frequency of TP53 alterations and their correlation with other genetic changes and outcome in acute myeloid leukemia with complex karyotype (CK-AML), we performed integrative analysis using TP53 mutational ... Prognostic value of monosomal karyotype in comparison to complex aberrant karyotype in acute myeloid leukemia: a study on 824 cases with aberrant karyotype [作者：Haferlach, C; Alpermann, T; Schnittger, S; Kern, W; Chromik, J; Schmid, C; Pielken, HJ; Kreuzer, KA; Hoffkes, HG; Haferlach, T,期刊：Blood, 页码：2122-2125 , 文章类型： Article，,卷期：2012年119-9] In acute myeloid leukemia (AML) the subset with complex karyotype (CK) is traditionally regarded as the worst prognostic group. However, >= 3, >= 4, or >= 5 abnormalities have been variably used for its definition. Recen... Macrophage LRP1 contributes to the clearance of von Willebrand factor [作者：Rastegarlari, G; Pegon, JN; Casari, C; Odouard, S; Navarrete, AM; Saint-Lu, N; van Vlijmen, BJ; Legendre, P; Christophe, OD; Denis, CV; Lenting, PJ,期刊：Blood, 页码：2126-2134 , 文章类型： Article，,卷期：2012年119-9] The relationship between low-density lipoprotein receptor-related protein-1 (LRP1) and von Willebrand factor (VWF) has remained elusive for years. Indeed, despite a reported absence of interaction between both proteins, ... VWF mutations and new sequence variations identified in healthy controls are more frequent in the African-American population [作者：Bellissimo, DB; Christopherson, PA; Flood, VH; Gill, JC; Friedman, KD; Haberichter, SL; Shapiro, AD; Abshire, TC; Leissinger, C; Hoots, WK; Lusher, JM; Ragni, MV; Montgomery, RR,期刊：Blood, 页码：2135-2140 , 文章类型： Article，,卷期：2012年119-9] Diagnosis and classification of VWD is aided by molecular analysis of the VWF gene. Because VWF polymorphisms have not been fully characterized, we performed VWF laboratory testing and gene sequencing of 184 healthy cont... Impact of graft-versus-host disease on outcomes after allogeneic hematopoietic cell transplantation for adult T-cell leukemia: a retrospective cohort study [作者：Kanda, J; Hishizawa, M; Utsunomiya, A; Taniguchi, S; Eto, T; Moriuchi, Y; Tanosaki, R; Kawano, F; Miyazaki, Y; Masuda, M; Nagafuji, K; Hara, M; Takanashi, M; Kai, S; Atsuta, Y; Suzuki, R; Kawase, T; Matsuo, K; Nagamura-Inoue, T; Kato, S; Sakamaki, H; Morishima, Y; Okamura, J; Ichinohe, T; Uchiyama, T,期刊：Blood, 页码：2141-2148 , 文章类型： Article，,卷期：2012年119-9] Allogeneic hematopoietic cell transplantation (HCT) is an effective treatment for adult T-cell leukemia (ATL), raising the question about the role of graft-versus-leukemia effect against ATL. In this study, we retrospect... Notch promotes vascular maturation by inducing integrin-mediated smooth muscle cell adhesion to the endothelial basement membrane [作者：Scheppke, L; Murphy, EA; Zarpellon, A; Hofmann, JJ; Merkulova, A; Shields, DJ; Weis, SM; Byzova, TV; Ruggeri, ZM; Iruela-Arispe, ML; Cheresh, DA,期刊：Blood, 页码：2149-2158 , 文章类型： Article，,卷期：2012年119-9] Vascular development and angiogenesis initially depend on endothelial tip cell invasion, which is followed by a series of maturation steps, including lumen formation and recruitment of perivascular cells. Notch ligands e... Overlapping and divergent signaling pathways of N-cadherin and VE-cadherin in endothelial cells [作者：Giampietro, C; Taddei, A; Corada, M; Sarra-Ferraris, GM; Alcalay, M; Cavallaro, U; Orsenigo, F; Lampugnani, MG; Dejana, E,期刊：Blood, 页码：2159-2170 , 文章类型： Article，,卷期：2012年119-9] Endothelial cells (ECs) express 2 members of the cadherin family, VE and N-cadherin. Although VE-cadherin induces EC homotypic adhesion, N-cadherin function in ECs remains largely unknown. EC-specific inactivation of eit... Experience with obatoclax mesylate (GX15-070), a small molecule pan-Bcl-2 family antagonist in patients with relapsed or refractory classical Hodgkin lymphoma [作者：Oki, Y; Copeland, A; Hagemeister, F; Fayad, LE; Fanale, M; Romaguera, J; Younes, A,期刊：Blood, 页码：2171-2172 , 文章类型： Letter，,卷期：2012年119-9] Recombinant factor VIIa (rFVIIa) and hemodialysis to manage massive dabigatran-associated postcardiac surgery bleeding [作者：Warkentin, TE; Margetts, P; Connolly, SJ; Lamy, A; Ricci, C; Eikelboom, JW,期刊：Blood, 页码：2172-2174 , 文章类型： Letter，,卷期：2012年119-9] Circulating immune complexes do not affect microparticle flow cytometry analysis in acute coronary syndrome [作者：Amabile, N; Renard, JM; Caussin, C; Boulanger, CM,期刊：Blood, 页码：2174-2175 , 文章类型： Letter，,卷期：2012年119-9]