- Novel Hepatitis C virus replicon inhibitors: Synthesis and structure-activity relationships of fused pyrimidine derivatives
[作者:Krueger, AC; Madigan, DL; Beno, DW; Betebenner, DA; Carrick, R; Green, BE; He, WP; Liu, DC; Maring, CJ; McDaniel, KF; Mo, HM; Molla, A; Motter, CE; Pilot-Matias, TJ; Tufano, MD; Kempf, DJ,期刊:Bioorganic & Medicinal Chemistry Letters, 页码:2212-2215 , 文章类型: Article,,卷期:2012年22-6]
- The synthesis of several pyrido[2,3-d] pyrimidine and pyrimido[4,5-d] pyrimidine analogs is described with one such analog possessing subnanomolar potency in both genotype 1a and 1b cell culture HCV replicon assays. (C) ...
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