- Design, synthesis, molecular docking and biological evaluation of new dithiocarbamates substituted benzimidazole and chalcones as possible chemotherapeutic agents
[作者:Bacharaju, K; Jambula, SR; Sivan, S; JyostnaTangeda, S; Manga, V,期刊:Bioorganic & Medicinal Chemistry Letters, 页码:3274-3277 , 文章类型: Article,,卷期:2012年22-9]
- A series of novel dithiocarbamates with benzimidazole and chalcone scaffold have been designed synthesised and evaluated for their antimitotic activity. Compounds 4c and 9d display the most promising antimitotic activity...
- Design, synthesis, and biological activity of novel 1,4-disubstituted piperidine/piperazine derivatives as CCR5 antagonist-based HIV-1 entry inhibitors
[作者:Dong, MX; Lu, L; Li, HT; Wang, XH; Lu, H; Jiang, SB; Dai, QY,期刊:Bioorganic & Medicinal Chemistry Letters, 页码:3284-3286 , 文章类型: Article,,卷期:2012年22-9]
- A series of novel 1,4-disubstituted piperidine/piperazine derivatives were designed, synthesized and evaluated for their in vitro activities against HIV-1 Bal (R5) infection in CEMX174 5.25M7 cells. A majority of these c...
|