- Histological demonstration of glucose transporters, fructose-1,6-bisphosphatase, and glycogen in gas gland cells of the swimbladder: Is a metabolic futile cycle operating?
[作者:Munakata, K; Ookata, K; Doi, H; Baba, O; Terashima, T; Hirose, S; Kato, A,期刊:Biochemical and Biophysical Research Communications, 页码:564-569 , 文章类型: Article,,卷期:2012年417-1]
- Luminal surface of the swimbladder is covered by gas gland epithelial cells and is responsible for inflating the swimbladder by generating O-2 from Root-effect hemoglobin that releases O-2 under acidic conditions. Acidif...
- Nicotine induces fibrogenic changes in human liver via nicotinic acetylcholine receptors expressed on hepatic stellate cells
[作者:Soeda, J; Morgan, M; McKee, C; Mouralidarane, A; Lin, C; Roskams, T; Oben, JA,期刊:Biochemical and Biophysical Research Communications, 页码:17-22 , 文章类型: Article,,卷期:2012年417-1]
- Background and aims: Cigarette smoke (CS) may cause liver fibrosis but possible involved mechanisms are unclear. Among the many chemicals in CS is nicotine - which affects cells through nicotinic acetylcholine receptors ...
- Role of Nanog in the maintenance of marrow stromal stem cells during post natal bone regeneration
[作者:Bais, MV; Shabin, ZM; Young, M; Einhorn, TA; Kotton, DN; Gerstnefeld, LC,期刊:Biochemical and Biophysical Research Communications, 页码:211-216 , 文章类型: Article,,卷期:2012年417-1]
- Post natal bone repair elicits a regenerative mechanism that restores the injured tissue to its pre-injury cellular composition and structure and is believed to recapitulate the embryological processes of bone formation....
- Early developmental expression of connexin26 in the cochlea contributes to its dominate functional role in the cochlear gap junctions
[作者:Qu, Y; Tang, WX; Zhou, BF; Ahmad, S; Chang, Q; Li, XM; Lin, X,期刊:Biochemical and Biophysical Research Communications, 页码:245-250 , 文章类型: Article,,卷期:2012年417-1]
- Mutations in Gjb2 and Gjb6 genes, coding for connexin26 (Cx26) and Cx30 proteins, respectively, are linked to about half of all cases of human autosomal non-syndromic prelingual deafness. Molecular mechanisms of the hear...
- Proteasome activity and autophagosome content in liver are reciprocally regulated by ethanol treatment
[作者:Thames, PG; Trambly, CS; Thiele, GM; Duryee, MJ; Fox, HS; Haorah, J; Donohue, TM,期刊:Biochemical and Biophysical Research Communications, 页码:262-267 , 文章类型: Article,,卷期:2012年417-1]
- The proteasome and autophagy are two major intracellular protein degradation pathways and the regulation of each by ethanol metabolism affects cellular integrity. Using acute and chronic ethanol feeding to mice in vivo, ...
- The expression and function of vascular endothelial growth factor in retinal pigment epithelial (RPE) cells is regulated by 4-hydroxynonenal (HNE) and glutathione S-transferaseA4-4
[作者:Vatsyayan, R; Lelsani, PCR; Chaudhary, P; Kumar, S; Awasthi, S; Awasthi, YC,期刊:Biochemical and Biophysical Research Communications, 页码:346-351 , 文章类型: Article,,卷期:2012年417-1]
- It is well established that 4-hydroxynonenal (HNE) plays a major role in oxidative stress-induced signaling and the toxicity of oxidants. Surprisingly our recent studies also demonstrate that low levels of HNE generated ...
- DNA methylation of the 5 '-untranslated region at+298 and+351 represses BACE1 expression in mouse BV-2 microglial cells
[作者:Byun, CJ; Seo, J; Jo, SA; Park, YJ; Klug, M; Rehli, M; Park, MH; Jo, I,期刊:Biochemical and Biophysical Research Communications, 页码:387-392 , 文章类型: Article,,卷期:2012年417-1]
- BACE1, which cleaves the amyloid precursor protein, is the rate-limiting enzyme for beta-amyloid peptide production, leading to the pathogenesis of Alzheimer's disease (AD). A high plasma level of homocysteine, acting as...
- Cell death is induced by ciglitazone, a peroxisome proliferator-activated receptor gamma (PPAR gamma) agonist, independently of PPAR gamma in human glioma cells
[作者:Lee, MW; Kim, DS; Kim, HR; Kim, HJ; Yang, JM; Ryu, S; Noh, YH; Lee, SH; Son, MH; Jung, HL; Yoo, KH; Koo, HH; Sung, KW,期刊:Biochemical and Biophysical Research Communications, 页码:552-557 , 文章类型: Article,,卷期:2012年417-1]
- Peroxisome proliferator-activated receptor gamma (PPAR gamma) regulates multiple signaling pathways, and its agonists induce apoptosis in various cancer cells. However, their role in cell death is unclear. In this study,...
- Two small molecule agonists of glucagon-like peptide-1 receptor modulate the receptor activation response differently
[作者:Cheong, YH; Kim, MK; Son, MH; Kaang, BK,期刊:Biochemical and Biophysical Research Communications, 页码:558-563 , 文章类型: Article,,卷期:2012年417-1]
- The glucagon-like peptide-1 receptor (GLP-1R) is a target for type 2 diabetes treatment. Due to the inconvenience of peptide therapeutics, small-molecule GLP-1R agonists have been studied. Compound 2 (6,7-dichloro-2-meth...
- Tumor suppressive microRNA-1 mediated novel apoptosis pathways through direct inhibition of splicing factor serine/arginine-rich 9 (SRSF9/SRp30c) in bladder cancer
[作者:Yoshino, H; Enokida, H; Chiyomaru, T; Tatarano, S; Hidaka, H; Yamasaki, T; Gotannda, T; Tachiwada, T; Nohata, N; Yamane, T; Seki, N; Nakagawa, M,期刊:Biochemical and Biophysical Research Communications, 页码:588-593 , 文章类型: Article,,卷期:2012年417-1]
- We have previously found that restoration of tumor suppressive microRNA-1 (miR-1), induced cell apoptosis in bladder cancer (BC) cell lines. However, the apoptosis mechanism induced by miR-1 was not fully elucidated. Alt...
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