- Acetylation of sphingosine kinase 1 regulates cell growth and cell-cycle progression
[作者:Yu, HY; Shao, Y; Gao, LH; Zhang, LC; Guo, KH; Wu, CT; Hu, XW; Duan, HF,期刊:Biochemical and Biophysical Research Communications, 页码:1242-1247 , 文章类型: Article,,卷期:2012年417-4]
- Sphingosine kinase 1 (SPK1) is a key enzyme in the sphingolipid metabolic pathway. It forms an essential checkpoint to regulate the relative levels of bioactive sphingolipid metabolites, ceramide, sphingosine, and sphing...
- Functional characterization of the pleckstrin homology domain of a cellulose synthase from the oomycete Saprolegnia monoica
[作者:Fugelstad, J; Brown, C; Hukasova, E; Sundqvist, G; Lindqvist, A; Bulone, V,期刊:Biochemical and Biophysical Research Communications, 页码:1248-1253 , 文章类型: Article,,卷期:2012年417-4]
- Some oomycetes, for instance Saprolegnia parasitica, are severe fish pathogens that cause important economic losses worldwide. Cellulose biosynthesis is a vital process for this class of microorganisms, but the correspon...
- Casuarinin suppresses TARC/CCL17 and MDC/CCL22 production via blockade of NF-kappa B and STAT1 activation in HaCaT cells
[作者:Kwon, DJ; Bae, YS; Ju, SM; Goh, AR; Youn, GS; Choi, SY; Park, J,期刊:Biochemical and Biophysical Research Communications, 页码:1254-1259 , 文章类型: Article,,卷期:2012年417-4]
- Casuarinin is a naturally occurring tannin that is isolated from the leaves of Hippophae rhamnoides. It has been shown to have anti-oxidant, anti-cancer, anti-viral, and anti-inflammatory activities. The aim of this stud...
- The matrix metalloproteinase-7 regulates the extracellular shedding of syndecan-2 from colon cancer cells
[作者:Choi, S; Kim, JY; Park, JH; Lee, ST; Han, IO; Oh, ES,期刊:Biochemical and Biophysical Research Communications, 页码:1260-1264 , 文章类型: Article,,卷期:2012年417-4]
- The cell surface heparan sulfate proteoglycan syndecan-2 regulates the activation of matrix metalloproteinase-7 (MMP-7) as a docking receptor. Here, we demonstrate the role of MMP-7 on syndecan-2 shedding in colon cancer...
- POTE protein, a cancer-testis antigen, is highly expressed in spermatids in human testis and is associated with apoptotic cells
[作者:Bera, TK; Walker, DA; Sherins, RJ; Pastan, I,期刊:Biochemical and Biophysical Research Communications, 页码:1271-1274 , 文章类型: Article,,卷期:2012年417-4]
- The POTE gene family encodes very closely related proteins that are highly expressed in testis and in many cancers. Recent studies indicate that the POTE proteins have a pro-apoptotic function. To examine if POTE is asso...
- Stevioside ameliorates high-fat diet-induced insulin resistance and adipose tissue inflammation by downregulating the NF-kappa B pathway
[作者:Wang, ZQ; Xue, LQ; Guo, CC; Han, B; Pan, CM; Zhao, SX; Song, HD; Ma, QY,期刊:Biochemical and Biophysical Research Communications, 页码:1280-1285 , 文章类型: Article,,卷期:2012年417-4]
- Accumulating evidence suggests that adipose tissue is the main source of pro-inflammatory molecules that predispose individuals to insulin resistance. Stevioside (SVS) is a widely used sweetener with multiple beneficial ...
- Structural evolution and tissue-specific expression of tetrapod-specific second isoform of secretory pathway Ca2+-ATPase
[作者:Pestov, NB; Dmitriev, RI; Kostina, MB; Korneenko, TV; Shakhparonov, MI; Modyanov, NN,期刊:Biochemical and Biophysical Research Communications, 页码:1298-1303 , 文章类型: Article,,卷期:2012年417-4]
- Secretory pathway Ca-ATPases are less characterized mammalian calcium pumps than plasma membrane Ca-ATPases and sarco-endoplasmic reticulum Ca-ATPases. Here we report analysis of molecular evolution, alternative splicing...
- Macrophage expression of LRP1, a receptor for apoptotic cells and unopsonized erythrocytes, can be regulated by glucocorticoids
[作者:Nilsson, A; Vesterlund, L; Oldenborg, PA,期刊:Biochemical and Biophysical Research Communications, 页码:1304-1309 , 文章类型: Article,,卷期:2012年417-4]
- Macrophage phagocytosis of apoptotic cells, or unopsonized viable CD47(-/-) red blood cells, can be mediated by the interaction between calreticulin (CRT) on the target cell and LDL receptor-related protein-1 (LRP1/CD91/...
- PMA induces GCMa phosphorylation and alters its stability via the PKC- and ERK-dependent pathway
[作者:Yasui, Y; Yamada, K; Takahashi, S; Sugiura-Ogasawara, M; Sato, K; Miyazawa, D; Sugiyama, T; Kitade, Y; Ueda, H,期刊:Biochemical and Biophysical Research Communications, 页码:1127-1132 , 文章类型: Article,,卷期:2012年417-4]
- The glial cells missing a (GCMa) transcription factor plays a pivotal role in the placental development by regulating the expression of several genes in the placenta that are responsible for the proper formation of the s...
- Characterization of germline antibody libraries from human umbilical cord blood and selection of monoclonal antibodies to viral envelope glycoproteins: Implications for mechanisms of immune evasion and design of vaccine immunogens
[作者:Chen, WZ; Streaker, ED; Russ, DE; Feng, Y; Prabakaran, P; Dimitrov, DS,期刊:Biochemical and Biophysical Research Communications, 页码:1164-1169 , 文章类型: Article,,卷期:2012年417-4]
- We have previously observed that all known HIV-1 broadly neutralizing antibodies (bnAbs) are highly divergent from germline antibodies in contrast to bnAbs against Hendra virus, Nipah virus and SARS coronavirus (SARS CoV...
- Mesenchymal stem cell isolation and characterization from human spinal ligaments
[作者:Asari, T; Furukawa, K; Tanaka, S; Kudo, H; Mizukami, H; Ono, A; Numasawa, T; Kumagai, G; Motomura, S; Yagihashi, S; Toh, S,期刊:Biochemical and Biophysical Research Communications, 页码:1193-1199 , 文章类型: Article,,卷期:2012年417-4]
- Mesenchymal stem cells (MSCs) have a fibroblast-like morphology, multilineage potential, long-term viability and capacity for self-renewal. While several articles describe isolating MSCs from various human tissues, there...
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