- The neutrophil recombinatorial TCR-like immune receptor is expressed across the entire human life span but repertoire diversity declines in old age
[作者:Fuchs, T; Puellmann, K; Scharfenstein, O; Eichner, R; Stobe, E; Becker, A; Pechlivanidou, I; Kzhyshkowska, J; Gratchev, A; Ganser, A; Neumaier, M; Beham, AW; Kaminski, WE,期刊:Biochemical and Biophysical Research Communications, 页码:309-315 , 文章类型: Article,,卷期:2012年419-2]
- Recent evidence has revealed the existence of T cell receptor (TCR) alpha beta-based recombinatorial immune receptors in phagocytes. Here, we performed a systematic survey of the variable beta-chain repertoires of the ne...
- Expression, purification, and characterization of a 2,3-dihydroxybiphenyl-1,2-dioxygenase from Bacillus sp JF8 in Escherichia coli
[作者:Bian, L; Shuai, JJ; Xiong, F; Peng, RH; Yao, QH; Xiong, AS,期刊:Biochemical and Biophysical Research Communications, 页码:339-343 , 文章类型: Article,,卷期:2012年419-2]
- 2,3-Dihydroxybiphenyl-1,2-dioxygenase plays an important role in the degradation of polychlorinated biphenyls. The gene (BsbphCI) encoding a 2,3-DHBP dioxygenase from Bacillus sp. JF8 is 960 bp. We synthesized a 960 bp B...
- Impaired fatty acid oxidation in a Drosophila model of mitochondrial trifunctional protein (MTP) deficiency
[作者:Kishita, Y; Tsuda, M; Aigaki, T,期刊:Biochemical and Biophysical Research Communications, 页码:344-349 , 文章类型: Article,,卷期:2012年419-2]
- Mitochondrial trifunctional protein (MTP), which consists of the MTP alpha and MTP beta subunits, catalyzes long-chain fatty acid beta-oxidation. MTP deficiency in humans results in Reye-like syndrome. Here, we generated...
- Cycling hypoxia up-regulates thioredoxin levels in human MDA-MB-231 breast cancer cells
[作者:Karlenius, TC; Shah, F; Di Trapani, G; Clarke, FM; Tonissen, KF,期刊:Biochemical and Biophysical Research Communications, 页码:350-355 , 文章类型: Article,,卷期:2012年419-2]
- The thioredoxin system is a key cellular antioxidant system and is highly expressed in cancer cells, especially in more aggressive and therapeutic resistant tumors. We analysed the expression of the thioredoxin system in...
- Rab27b regulates c-kit expression by controlling the secretion of stem cell factor
[作者:Tanaka, C; Kaji, H; He, JS; Hazama, R; Yokoyama, K; Kinoshita, E; Tsujioka, T; Tohyama, K; Yamamura, H; Nishio, H; Tohyama, Y,期刊:Biochemical and Biophysical Research Communications, 页码:368-373 , 文章类型: Article,,卷期:2012年419-2]
- Rab27b, a subfamily of Rab27 small GTPases, was originally identified in platelets. However, the role of Rab27b in megakaryocytic lineage cells remains unknown. Here, using a human megakaryoblastic cell line, CMK, we sho...
- Involvement of P2X4 receptor in P2X7 receptor-dependent cell death of mouse macrophages
[作者:Kawano, A; Tsukimoto, M; Noguchi, T; Hotta, N; Harada, H; Takenouchi, T; Kitani, H; Kojima, S,期刊:Biochemical and Biophysical Research Communications, 页码:374-380 , 文章类型: Article,,卷期:2012年419-2]
- Interaction of P2X7 receptor with P2X4 receptor has recently been suggested, but it remains unclear whether P2X4 receptor is involved in P2X7 receptor-mediated events, such as cell death of macrophages induced by high co...
- KLF10, transforming growth factor-beta-inducible early gene 1, acts as a tumor suppressor
[作者:Song, KD; Kim, DJ; Lee, JE; Yun, CH; Lee, WK,期刊:Biochemical and Biophysical Research Communications, 页码:388-394 , 文章类型: Article,,卷期:2012年419-2]
- Kruppel-like factor 10 (KLF10) has been suggested to be a putative tumor suppressor. In the present study, we generated KLF10 deficient mice to explore this hypothesis in vivo. KLF10 deficient mice exhibited increased pr...
- PPAR alpha and PPAR gamma regulate the nucleoside transporter hENT1
[作者:Montero, TD; Racordon, D; Bravo, L; Owen, GI; Bronfman, ML; Leisewitz, AV,期刊:Biochemical and Biophysical Research Communications, 页码:405-411 , 文章类型: Article,,卷期:2012年419-2]
- Human equilibrative nucleoside transporter 1 (hENT1) is an important determinant for nucleoside analog based chemotherapy success. Preliminary data suggest hENT1 regulation by PPARs. Using A2780 cells, we investigated th...
- XIAP reverses various functional activities of FRNK in endothelial cells
[作者:Ahn, S; Kim, HJ; Chi, SG; Park, H,期刊:Biochemical and Biophysical Research Communications, 页码:419-424 , 文章类型: Article,,卷期:2012年419-2]
- In endothelial cells, focal adhesion kinase (FAK) regulates cell proliferation, migration, adhesion, and shear-stimulated activation of MAPK. We recently found that FAK is recruited into focal adhesion (FA) sites through...
- Triiodothyronine stimulates cystatin C production in bone cells
[作者:Schmid, C; Ghirlanda-Keller, C; Zwimpfer, C; Zoidis, E,期刊:Biochemical and Biophysical Research Communications, 页码:425-430 , 文章类型: Article,,卷期:2012年419-2]
- Thyroid hormones increase cystatin C levels in vivo. To study whether 3,3',5-triiodo-L-thyronine (T-3) stimulates the production of cystatin C in vitro, we used a T-3-responsive osteoblastic cell line (PyMS) which can be...
|