- Up-regulated miR-17 promotes cell proliferation, tumour growth and cell cycle progression by targeting the RND3 tumour suppressor gene in colorectal carcinoma
[作者:Luo, HS; Zou, JJ; Dong, ZY; Zeng, Q; Wu, DH; Liu, L,期刊:Biochemical Journal, 页码:311-321 , 文章类型: Article,,卷期:2012年442-2]
- Emerging evidence indicates that the miR-17 family may have a causal role in human cancer tumorigenesis, but their specific effects on the occurrence of CRC (colorectal carcinoma) are still poorly understood. In the pres...
- Hydroperoxide and peroxynitrite reductase activity of poplar thioredoxin-dependent glutathione peroxidase 5: kinetics, catalytic mechanism and oxidative inactivation
[作者:Selles, B; Hugo, M; Trujillo, M; Srivastava, V; Wingsle, G; Jacquot, JP; Radi, R; Rouhier, N,期刊:Biochemical Journal, 页码:369-380 , 文章类型: Article,,卷期:2012年442-2]
- Gpxs (glutathione peroxidases) constitute a family of peroxidases, including selenocysteine- or cysteine-containing isoforms (SeCys-Gpx or Cys-Gpx), which are regenerated by glutathione or Trxs (thioredoxins) respectivel...
- Membrane integration of a mitochondrial signal-anchored protein does not require additional proteinaceous factors
[作者:Merklinger, E; Gofman, Y; Kedrov, A; Driessen, AJM; Ben-Tal, N; Shai, Y; Rapaport, D,期刊:Biochemical Journal, 页码:381-389 , 文章类型: Article,,卷期:2012年442-2]
- The MOM (mitochondrial outer membrane) contains SA (signal-anchored) proteins that bear at their N-terminus a single hydrophobic segment that serves as both a mitochondria] targeting signal and an anchor at the membrane....
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