- Solution structure of the Pdp1 PWWP domain reveals its unique binding sites for methylated H4K20 and DNA
[作者：Qiu, Y; Zhang, W; Zhao, C; Wang, Y; Wang, WW; Zhang, JH; Zhang, ZY; Li, GH; Shi, YY; Tu, XM; Wu, JH,期刊：Biochemical Journal, 页码：527-538 , 文章类型： Article，,卷期：2012年442-3]
- Methylation of H4K20 (Lys(20) of histone H4) plays an important role in the regulation of diverse cellular processes. In fission yeast, all three states of H4K20 methylation are catalysed by Set9. Pdp1 is a PWWP (proline...
- Human-protein-derived peptides for intracellular delivery of biomolecules
[作者：Haas, AK; Maisel, D; Adelmann, J; von Schwerin, C; Kahnt, I; Brinkmann, U,期刊：Biochemical Journal, 页码：583-593 , 文章类型： Article，,卷期：2012年442-3]
- Access of therapeutic biomolecules to cytoplasmic and nuclear targets is hampered by the inability of these molecules to cross biological membranes. Approaches to overcome this hurdle involve CPPs (cell-penetrating pepti...
- A novel non-canonical mechanism of regulation of MST3 (mammalian Sterile20-related kinase 3)
[作者：Fuller, SJ; McGuffin, LJ; Marshall, AK; Giraldo, A; Pikkarainen, S; Clerk, A; Sugden, PH,期刊：Biochemical Journal, 页码：595-610 , 文章类型： Article，,卷期：2012年442-3]
- The canonical pathway of regulation of the GCK (germinal centre kinase) III subgroup member, MST3 (mammalian Sterile20-related kinase 3), involves a caspase-mediated cleavage between N-terminal catalytic and C-terminal r...
- Targeting Lyn tyrosine kinase through protein fusions encompassing motifs of Cbp (Csk-binding protein) and the SOCS box of SOCS1
[作者：Whiting, RJ; Payne, CJ; Satiaputra, J; Kucera, N; Qiu, TW; Irtegun, S; Gunn, NJ; Lavova-Azmanova, NS; Mulhern, TD; Ingley, E,期刊：Biochemical Journal, 页码：611-620 , 文章类型： Article，,卷期：2012年442-3]
- The tyrosine kinase Lyn is involved in oncogenic signalling in several leukaemias and solid tumours, and we have previously identified a pathway centred on Cbp [Csk (C-terminal Src kinase)-binding protein] that mediates ...
- A cohesin-RAD21 interactome
[作者：Panigrahi, AK; Zhang, NG; Otta, SK; Pati, D,期刊：Biochemical Journal, 页码：661-670 , 文章类型： Article，,卷期：2012年442-3]
- The cohesin complex holds the sister chromatids together from S-phase until the metaphase-to-anaphase transition, and ensures both their proper cohesion and timely separation. In addition to its canonical function in chr...
- Identification of autophosphorylation sites in eukaryotic elongation factor-2 kinase
[作者：Ruys, SPD; Wang, XM; Smith, EM; Herinckx, G; Hussain, N; Rider, MH; Vertommen, D; Proud, CG,期刊：Biochemical Journal, 页码：681-692 , 文章类型： Article，,卷期：2012年442-3]
- eEF2K [eEF2 (eukaryotic elongation factor 2) kinase] phosphorylates and inactivates the translation elongation factor eEF2. eEF2K is not a member of the main eukaryotic protein kinase superfamily, but instead belongs to ...
- I kappa B kinase beta (IKK beta) does not mediate feedback inhibition of the insulin signalling cascade
[作者：Lancaster, GI; Skiba, B; Yang, C; Nicholls, HLT; Langley, KG; Chan, MHS; Bruce, CR; Rewcastle, GW; Shepherd, PR; Karin, M; Febbraio, MA,期刊：Biochemical Journal, 页码：723-732 , 文章类型： Article，,卷期：2012年442-3]
- In the present study, we have examined whether IKK beta [I kappa B (inhibitor of nuclear factor kappa B)kinase beta] plays a role in feedback inhibition of the insulin signalling cascade. Insulin induces the phosphorylat...
- 2-Carboxy-D-arabinitol 1-phosphate (CA1P) phosphatase: evidence for a wider role in plant Rubisco regulation
[作者：Andralojc, PJ; Madgwick, PJ; Tao, Y; Keys, A; Ward, JL; Beale, MH; Loveland, JE; Jackson, PJ; Willis, AC; Gutteridge, S; Parry, MAJ,期刊：Biochemical Journal, 页码：733-742 , 文章类型： Article，,卷期：2012年442-3]
- The genes for CA 1 Pase (2-carboxy-D-arabinito1-1-bisphosphate phosphatase) from French bean, wheat. Arabidopsis and tobacco were identified and cloned. The deduced protein sequence included an N-terminal motif identical...
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