- Absence of ABCG2-mediated mucosal detoxification in patients with active inflammatory bowel disease is due to impeded protein folding
[作者:Deuring, JJ; de Haar, C; Koelewijn, CL; Kuipers, EJ; Peppelenbosch, MP; van der Woude, CJ,期刊:Biochemical Journal, 页码:87-93 , 文章类型: Article,,卷期:2012年441-1]
- Xenotoxic damage in inflammatory diseases, including IBD (inflammatory bowel disease), is compounded by reduced activity of the xenobiotic transporter ABCG2 (ATP-binding-cassette G2) during the inflammatory state. An ass...
- Dissecting structure-function-stability relationships of a thermostable GH5-CBM3 cellulase from Bacillus subtilis 168
[作者:Santos, CR; Paiva, JH; Sforca, ML; Neves, JL; Navarro, RZ; Cota, J; Akao, PK; Hoffmam, ZB; Meza, AN; Smetana, JH; Nogueira, ML; Polikarpov, I; Xavier-Neto, J; Squina, FM; Ward, RJ; Ruller, R; Zeri, AC; Murakami, MT,期刊:Biochemical Journal, 页码:95-104 , 文章类型: Article,,卷期:2012年441-1]
- Cellulases participate in a number of biological events, such as plant cell wall remodelling, nematode parasitism and microbial carbon uptake. Their ability to depolymerize crystalline cellulose is of great biotechnologi...
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