- FMN-coated fluorescent iron oxide nanoparticles for RCP-mediated targeting and labeling of metabolically active cancer and endothelial cells
[作者:Jayapaul, J; Hodenius, M; Arns, S; Lederle, W; Lammers, T; Comba, P; Kiessling, F; Gaetjens, J,期刊:BIOMATERIALS, 页码:5863-5871 , 文章类型: Article,,卷期:2011年32-25]
- Riboflavin is an essential vitamin for cellular metabolism and is highly upregulated in metabolically active cells. Consequently, targeting the riboflavin carrier protein (RCP) may be a promising strategy for labeling ca...
- Peptide-conjugated polymeric micellar nanoparticles for Dual SPECT and optical imaging of EphB4 receptors in prostate cancer xenografts
[作者:Zhang, R; Xiong, CY; Huang, M; Zhou, M; Huang, Q; Wen, XX; Liang, D; Li, C,期刊:BIOMATERIALS, 页码:5872-5879 , 文章类型: Article,,卷期:2011年32-25]
- EphB4, a member of the largest family of receptor tyrosine kinases, is overexpressed in numerous tumors. In this study, we developed a new class of multimodal nanoplatform for dual single photon emission computed tomogra...
- Aggregation-enhanced fluorescence in PEGylated phospholipid nanomicelles for in vivo imaging
[作者:Wang, D; Qian, J; He, SL; Park, JS; Lee, KS; Han, SH; Mu, Y,期刊:BIOMATERIALS, 页码:5880-5888 , 文章类型: Article,,卷期:2011年32-25]
- We report polymeric nanomicelles doped with organic fluorophores (StCN, (Z)-2,3-bis[4-(N-4-(diphenylamino)styryl)phenyl]-acrylonitrile), which have the property of aggregation-enhanced fluorescence. The fluorescent nanom...
- Enhanced gene expression in tumors after intravenous administration of arginine-, lysine- and leucine-bearing polypropylenimine polyplex
[作者:Aldawsari, H; Edrada-Ebel, R; Blatchford, DR; Tate, RJ; Tetley, L; Dufes, C,期刊:BIOMATERIALS, 页码:5889-5899 , 文章类型: Article,,卷期:2011年32-25]
- The possibility of using non-viral gene delivery systems for the treatment of cancer is currently limited by their lower transfection efficacy compared to viral systems. On the basis that amino acids such as arginine, ly...
- The use of cationic nanogels to deliver proteins to myeloma cells and primary T lymphocytes that poorly express heparan sulfate
[作者:Watanabe, K; Tsuchiya, Y; Kawaguchi, Y; Sawada, S; Ayame, H; Akiyoshi, K; Tsubata, T,期刊:BIOMATERIALS, 页码:5900-5905 , 文章类型: Article,,卷期:2011年32-25]
- Fusion proteins containing protein transduction domain (PTD) are widely used for intracellular delivery of exogenous proteins. PTD-mediated delivery requires expression of heparan sulfate on the surface of the target cel...
- Encapsulation of curcumin in self-assembling peptide hydrogels as injectable drug delivery vehicles
[作者:Altunbas, A; Lee, SJ; Rajasekaran, SA; Schneider, JP; Pochan, DJ,期刊:BIOMATERIALS, 页码:5906-5914 , 文章类型: Article,,卷期:2011年32-25]
- Curcumin, a hydrophobic polyphenol, is an extract of turmeric root with antioxidant, anti-inflammatory and anti-tumorigenic properties. Its lack of water solubility and relatively low bioavailability set major limitation...
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