- The suppression of prostate LNCaP cancer cells growth by Selenium nanoparticles through Akt/Mdm2/AR controlled apoptosis
[作者:Kong, L; Yuan, Q; Zhu, H; Li, Y; Guo, Q; Wang, Q; Bi, X; Gao, X,期刊:BIOMATERIALS, 页码:6515-6522 , 文章类型: Article,,卷期:2011年32-27]
- The trace element Selenium is suggested having cancer prevention activity and used as food supplement. Previous results had shown Selenium nanoparticles are safer compared with other Selenium compounds like selenomethion...
- Self-protecting core-shell magnetic nanoparticles for targeted, traceable, long half-life delivery of BCNU to gliomas
[作者:Yang, HW; Hua, MY; Liu, HL; Huang, CY; Tsai, RY; Lu, YJ; Chen, JY; Tang, HJ; Hsien, HY; Chang, YS; Yen, TC; Chen, PY; Wei, KC,期刊:BIOMATERIALS, 页码:6523-6532 , 文章类型: Article,,卷期:2011年32-27]
- The successful delivery of anti-cancer drugs relies on the simultaneous capability to actively target a specific location, a sufficient lifetime in the active form in the circulation, and traceability and quantification ...
- Uridine-based paramagnetic supramolecular nanoaggregate with high relaxivity capable of detecting primitive liver tumor lesions
[作者:Bhuniya, S; Moon, H; Lee, H; Hong, KS; Lee, S; Yu, DY; Kim, JS,期刊:BIOMATERIALS, 页码:6533-6540 , 文章类型: Article,,卷期:2011年32-27]
- The water soluble uridine-based paramagnetic self-assembled amphiphilic molecules (LGd2-5) with DTTA binding site were synthesized and have been characterized in regard to their T(1) magnetic resonance imaging (MRI) cont...
- Patterning and detailed study of human hNT astrocytes on parylene-C/silicon dioxide substrates to the single cell level
[作者:Unsworth, CP; Holloway, H; Delivopoulos, E; Murray, AF; Simpson, MC; Dickinson, ME; Graham, ES,期刊:BIOMATERIALS, 页码:6541-6550 , 文章类型: Article,,卷期:2011年32-27]
- It is estimated that the adult human brain contains 100 billion neurons with 5-10 times as many astrocytes. Although it has been generally considered that the astrocyte is a simple supportive cell to the neuron, recent r...
- A metabonomic analysis of organ specific response to USPIO administration
[作者:Feng, JH; Liu, HL; Bhakoo, KK; Lu, LH; Chen, Z,期刊:BIOMATERIALS, 页码:6558-6569 , 文章类型: Article,,卷期:2011年32-27]
- As ultrasmall superparamagnetic particles of iron oxides (USPIO) have been widely used in clinical medicine as MRI contrast agents, hence their potential toxicity and adverse effects following administration have attract...
- MRI monitoring of intratumoral drug delivery and prediction of the therapeutic effect with a multifunctional thermosensitive liposome
[作者:Tagami, T; Foltz, WD; Ernsting, MJ; Lee, CM; Tannock, IF; May, JP; Li, SD,期刊:BIOMATERIALS, 页码:6570-6578 , 文章类型: Article,,卷期:2011年32-27]
- Non-invasive in vivo imaging of drug distribution enables real-time monitoring and prediction of therapeutic responses to treatment. We have developed a thermosensitive liposomal formulation (HaT: Hyperthermia-activated-...
- Nanosheet-based titania microspheres with hollow core-shell structure encapsulating horseradish peroxidase for a mediator-free biosensor
[作者:Xie, Q; Zhao, YY; Chen, X; Liu, HM; Evans, DG; Yang, WS,期刊:BIOMATERIALS, 页码:6588-6594 , 文章类型: Article,,卷期:2011年32-27]
- Nanosheet-based titania (TiO(2)) microspheres with a hollow core-shell structure have been synthesized and employed to immobilize horseradish peroxidase (HRP) in order to fabricate a mediator-free biosensor. The morpholo...
- Amphiphilic multiarm star block copolymer-based multifunctional unimolecular micelles for cancer targeted drug delivery and MR imaging
[作者:Li, XJ; Qian, YF; Liu, T; Hu, XL; Zhang, GY; You, YZ; Liu, SY,期刊:BIOMATERIALS, 页码:6595-6605 , 文章类型: Article,,卷期:2011年32-27]
- We report on the fabrication of multifunctional polymeric unimolecular micelles as an integrated platform for cancer targeted drug delivery and magnetic resonance imaging (MRI) contrast enhancement under in vitro and in ...
- Targeted delivery of antibiotics to intracellular chlamydial infections using PLGA nanoparticles
[作者:Toti, US; Guru, BR; Hali, M; McPharlin, CM; Wykes, SM; Panyam, J; Whittum-Hudson, JA,期刊:BIOMATERIALS, 页码:6606-6613 , 文章类型: Article,,卷期:2011年32-27]
- Chlamydia trachomatis and Chlamydia pneumoniae are intracellular bacterial pathogens that have been shown to cause, or are strongly associated with, diverse chronic diseases. Persistent infections by both organisms are r...
- Delivery of calf thymus DNA to tumor by folate receptor targeted cationic liposomes
[作者:Li, H; Piao, LZ; Yu, B; Yung, BC; Zhang, WP; Wang, PG; Lee, JL; Lee, RJ,期刊:BIOMATERIALS, 页码:6614-6620 , 文章类型: Article,,卷期:2011年32-27]
- Calf thymus DNA (ctDNA) has been shown to stimulate macrophages to produce cytokines both in vitro and in vivo when complexed with cationic liposomes. In addition, direct cytotoxicity of ctDNA has been found in tissue cu...
- The effect of purity upon the triple-helical stability of collagenous peptides
[作者:Slatter, DA; Bihan, DG; Farndale, RW,期刊:BIOMATERIALS, 页码:6621-6632 , 文章类型: Article,,卷期:2011年32-27]
- Collagen is the fundamental structural protein, comprising 25-35% of the total body protein, its rod-like triple helix providing support in many tissues. Our laboratory has synthesised 113 Toolkit peptides, each 63 resid...
- Well-defined, reversible disulfide cross-linked micelles for on-demand paclitaxel delivery
[作者:Li, YP; Xiao, K; Luo, JT; Xiao, WW; Lee, JS; Gonik, AM; Kato, J; Dong, TA; Lam, KS,期刊:BIOMATERIALS, 页码:6633-6645 , 文章类型: Article,,卷期:2011年32-27]
- To minimize premature release of drugs from their carriers during circulation in the blood stream, we have recently developed reversible disulfide cross-linked micelles (DCMs) that can be triggered to release drug at the...
- Biodegradation, biocompatibility, and drug delivery in poly (omega-pentadecalactone-co-p-dioxanone) copolyesters
[作者:Liu, J; Jiang, ZZ; Zhang, SM; Liu, C; Gross, RA; Kyriakides, TR; Saltzman, WM,期刊:BIOMATERIALS, 页码:6646-6654 , 文章类型: Article,,卷期:2011年32-27]
- Poly(omega-pentadecalactone-co-p-dioxanone) [poly(PDL-co-DO)] copolyesters are copolymers of an iso-dimorphic system, which remain semicrystalline over the whole range of compositions. Here, we evaluated enzymatically sy...
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