个性化文献订阅>文章检索

文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共35条记录   Identification of Tetrahydropyrido[4,3-d]pyrimidine Amides as a New Class of Orally Bioavailable TGR5 Agonists [作者：PIOTROWSKI DAVID W; FUTATSUGI KENTARO; WARMUS JOSEPH S; ORR SUVI T M; FREEMANCOOK KEVIN D; LONDREGAN ALLYN T; WEI LIUQING; JENNINGS SANDRA M; HERR MICHAEL; COFFEY STEVEN B; JIAO WENHUA; STORER GREGORY; HEPWORTH DAVID; WANG JIAN; LAVERGNE SOPHIE Y; CHIN JANICE E; HADCOCK JOHN R; BRENNER MARTIN B; WOLFORD ANGELA C; JANSSEN ANN M; ROUSH NICOLE S; BUXTON JOANNE; HINCHEY TERRI; KALGUTKAR AMIT S; SHARMA RAMAN; FLYNN DECLAN A,期刊：ACS Medicinal Chemistry Letters, 页码：63-68 , 文章类型： Article，,卷期：2013年4-1] Takeda G-protein-coupled receptor 5 (TGR5) represents an exciting biological target for the potential treatment of diabetes and metabolic syndrome. A new class of high-throughput screening (HTS)-derived tetrahydropyrido[... Synthesis and Anti-inflammatory Evaluation of Novel Benzimidazole and Imidazopyridine Derivatives [作者：CHEN GAOZHI; LIU ZHIGUO; ZHANG YALI; SHAN XIAOOU; JIANG LILI; ZHAO YUNJIE; HE WENFEI; FENG ZHIGUO; YANG SHULIN; LIANG GUANG,期刊：ACS Medicinal Chemistry Letters, 页码：69-74 , 文章类型： Article，,卷期：2013年4-1] Sepsis, an acute inflammatory disease, remains the most common cause of death in intensive care units. A series of benzimidazole and imidazopyridine derivatives were synthesized and screened for anti-inflammatory activit... HDAC Inhibitors as Targeted Treatment of Frontotemporal Lobar Degeneration [作者：ROSSE GERARD,期刊：ACS Medicinal Chemistry Letters, 页码：7-7 , 文章类型： Editorial Material，,卷期：2013年4-1]