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文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共94条记录   SYNTHESIS OF HUMAN CANCER ASSOCIATED GLOBO-H (MBR1) GLYCOSYLAMINO ACID: SOME MECHANISTIC AND CONFORMATIONAL REINVESTIGATIONS [作者：ZHU JIANGLONG; WAN QIAN; YANG GUANGBIN; OUERFELLI OUATHEK; DANISHEFSKY SAMUEL J,期刊：Heterocycles, 页码：441-449 , 文章类型： Article，,卷期：2009年79-1] The synthesis of an extended globo-H (MBr1 antigen) in the form of a glycosylamino acid is reported. By careful NMR analysis, we found an interesting conformational "flip" on the E ring of some synthetic intermediates. A... OUT-OF-PLANE DEFORMATION OF THE AZULENE RING ALONG ITS SHORT MOLECULAR AXIS IN CRYSTAL AND THEORETICAL STRUCTURES OF 1,3-DIHETEROLYL- AND 1,3-DIPHENYLAZULENES [作者：OHTA AKIRA; KURODA SHIGEYASU; THANH NGUYEN CHUNG; TERASAWA KOUHEI B; FUJIMORI KUNIHIDE; NAKAJIMA KEITA; ODA MITSUNORI,期刊：Heterocycles, 页码：451-470 , 文章类型： Article，,卷期：2009年79-1] Crystal structures of four simple azulene derivatives, 1,3-diheterolyl- and 1,3-diphenylazulenes, were determined by X-ray diffraction analysis. Three of them showed clear out-of-plane deformation of the azulene ring alo... SUBTLE CONTROL IN SOLUTION AND CRYSTAL STRUCTURES WITH WEAK HYDROGEN BONDS: THE UNUSUAL PROFILE OF DIMETHYL 3, 12-DIOXO-7, 8 DITHIA 4, 11-DIAZABICYCLO[12.2.2]OCTADECA-1(16), 14, 17-TRIENE 5, 10-DICARBOXYLATE (TDA1) [作者：KARLE ISABELLA L; HUANG LULU; VENKATESHWARLU PUNNA; SARMA A V S; RANGANATHAN SUBRAMANIA,期刊：Heterocycles, 页码：471-486 , 文章类型： Article，,卷期：2009年79-1] The structural features of the title compound were determined or examined by three diverse procedures: single crystal X-ray diffraction analysis, solution spectroscopic procedures and quantum mechanical theoretical calcu... SYNTHESIS AND BIOLOGICAL EVALUATION OF INHIBITORS OF BOTULINUM NEUROTOXIN METALLOPROTEASE [作者：WANG CHENBO; WIDOM JULIA; PETRONIJEVIC FILIP; BURNETT JAMES C; NUSS JONATHAN E; BAVARI SINA; GUSSIO RICK; WIPF PETER,期刊：Heterocycles, 页码：487-520 , 文章类型： Article，,卷期：2009年79-1] Based on the lead therapeutic agent NSC 240898, a new series of heterocyclic inhibitors of the BoNT serotype A metalloprotease has been generated. Highlights of the synthetic sequences include Sonogashira couplings of po... DE NOVO ASYMMETRIC APPROACH TO 8a-epi-SWAINSONINE [作者：CORAL JASON A; GUO HAIBING; SHAN MINGDE; ODOHERTY GEORGE A,期刊：Heterocycles, 页码：521-529 , 文章类型： Article，,卷期：2009年79-1] An improved method for the synthesis of (-)-8a-epi-swainsonine has been developed with 9 fewer steps than the original route. The synthetic improvements include a two-step procedure for the preparation of benzyl 4-(furan... SYNTHESIS, STRUCTURE AND CATALYTIC ACTIVITY OF MACROCYCLIC NHC PD PINCER COMPLEXES [作者：WATARAI NORIAKI; KAWASAKI HIROYASU; AZUMAYA ISAO; YAMASAKI RYU; SAITO SHINICHI,期刊：Heterocycles, 页码：531-548 , 文章类型： Article，,卷期：2009年79-1] We synthesized a series of new N-heterocyclic carbene (NHC) macrocyclic Pd pincer complexes (17-22) by the reaction of Pd(OAC)(2) or Pd-2(dba)(3) with the corresponding macrocycles, which were prepared by the coupling re... AN EFFICIENT SYNTHESIS OF PROCYANIDINS USING EQUIMOLAR CONDENSATION OF CATECHIN AND/OR EPICATECHIN CATALYZED BY YTTERBIUM TRIFLATE [作者：MOHRI YOSHIHIRO; SAGEHASHI MASAYOSHI; YAMADA TAIJI; HATTORI YASUNAO; MORIMURA KEIJI; HAMAUZU YASUNORI; KAMO TSUNASHI; HIROTA MITSURU; MAKABE HIDEFUMI,期刊：Heterocycles, 页码：549-563 , 文章类型： Article，,卷期：2009年79-1] Stereoselective synthesis of catechin and epicatechin dimers under intermolecular condensation of equimolar amount of catechin derivatives catalyzed by Yb(OTf)(3). The coupled products were successfully converted to proc... SYNTHESIS, DETERMINATION OF THE ABSOLUTE STEREOCHEMISTRY, AND EVALUATIONS AT THE NICOTINIC ACETYLCHOLINE RECEPTORS OF A HYDROXYINDOLIZIDINE ALKALOID FROM THE ANT MYRMICARIA MELANOGASTER [作者：ZHOU DEJUN; TOYOOKA NAOKI; NEMOTO HIDEO; YAMAGUCHI KAORU; TSUNEKI HIROSHI; WADA TSUTOMU; SASAOKA TOSHIYASU; SAKAI HIDEKI; TEZUKA YASUHIRO; KADOTA SHIGETOSHI; JONES TAPPEY H; GARRAFFO H MARTIN; SPANDE THOMAS F; DALY JOHN W,期刊：Heterocycles, 页码：565-571 , 文章类型： Article，,卷期：2009年79-1] The first chiral synthesis of new hydroxyindolizidine alkaloid (1) detected in the ant Myrmicaria melanogaster has been achieved, and its absolute stereochemistry was determined to be 3S, 5R, 8S, 9S by the present chiral... ASYMMETRIC SYNTHESIS OF 4-SUBSTITUTED 2,6-DIOXOPIPERIDINE-3-CARBONITRILE BY USING THIOUREA-CATALYZED ASYMMETRIC MICHAEL ADDITION [作者：INOKUMA TSUBASA; NAGAMOTO YUUKI; SAKAMOTO SHOTA; MIYABE HIDETO; TAKASU KIYOSEI; TAKEMOTO YOSHIJI,期刊：Heterocycles, 页码：573-582 , 文章类型： Article，,卷期：2009年79-1] An enantioselective Michael addition of several alpha,beta-unsaturated carbonyl compounds with malononitrile catalyzed by a bifunctional thiourea is described. We also demonstrate the transformation of Michael adduct int... DIOICINE: A NOVEL PRENYLATED PURINE ALKALOID FROM GYMNOCLADUS DIOICUS [作者：FITCH RICHARD W; SPANDE THOMAS F; GARRAFFO H MARTIN; CHASE RACHAEL R; CLINEDINST MYLAKA A; PARKES DEREK A; REED RICHARD; WHITTAKER NOEL F; DALY JOHN W,期刊：Heterocycles, 页码：583-598 , 文章类型： Article，,卷期：2009年79-1] The Kentucky coffeetree, Gymnocladus dioicus (L., K. Koch) is a leguminous tree reputed to be toxic to livestock and to contain the toxic nicotinic acetylcholine receptor agonist cytisine. Analysis of extracts of various... REACTION OF beta-TRIFLUOROACETYLKETENE ACETALS AND beta-TRIFLUOROACETYLVINYL ETHERS WITH 1,2-PHENYLENEDIAMINES ACCESSING FLUORINE-CONTAINING BENZO[b][1,4]DIAZEPINE DERIVATIVES: A MOLECULAR ORBITAL CALCULATION STUDY [作者：OTA NORIO; KAMITORI YASUHIRO; TERAI NAOYA; SAKATA TSUNEAKI; OKADA ETSUJI,期刊：Heterocycles, 页码：599-608 , 文章类型： Article，,卷期：2009年79-1] beta-Trifluoroacetylketene acetals (1) were found to react easily with 1,2-phenylenediamines to give dihydrobenzodiazepinols (5a) together with benzodiazepines (6a) under very mild conditions. In contrast, beta-trifluoro... SYNTHESIS OF AZA-BRIDGED CALIX(4-METHOXY)TRIAZINES TOWARD FLATTENED pi-CONJUGATED MACROCYCLES [作者：TANAKA HIROYUKI; WADA AYAKO; SHIRO MOTOO; HIOKI KAZUHITO; MORISAKI DAIKI; KUNISHIMA MUNETAKA,期刊：Heterocycles, 页码：609-616 , 文章类型： Article，,卷期：2009年79-1] Calixtriazines containing a 4-alkoxy-1,3,5-triazine backbone were efficiently synthesized by sequential fragment coupling started from 4-alkoxy-2,6-dichrolo-1,3,5-triazine. These macrocycles tend to form flattened confor... John W. Daly - An Appreciation [作者：JACOBSON KENNETH A; KIRK KENNETH L,期刊：Heterocycles, 页码：61-71 , 文章类型： Biographical-Item，,卷期：2009年79-1] John W. Daly was engaged in groundbreaking basic research for nearly 50 years at NIH in Bethesda, Maryland. A primary focus of his research included the discovery, structure elucidation, synthesis and pharmacology of alk... A NEW TRIMERIC HYDROLYZABLE TANNIN, OENOTHERIN T-2, ISOLATED FROM AERIAL PARTS OF OENOTHERA TETRAPTERA CAV. [作者：TANIGUCHI SHOKO; IMAYOSHI YOKO; YOSHIDA TAKASHI; HATANO TSUTOMU,期刊：Heterocycles, 页码：617-626 , 文章类型： Article，,卷期：2009年79-1] A new hydrolyzable tannin, oenotherin T-2, was isolated from the aerial parts of Oenothera tetraptera Cav., together with 15 known polyphenolic compounds. The trimeric structure of oenotherin T-2 was elucidated based on ... SYNTHESIS OF 1,2,4-TRIAZIN-5-ONES THROUGH [4+2] CYCLOADDITION OF 1,2,4-TRIAZA-1,3-DIENES WITH DIPHENYLKETENE [作者：NAKAI TATSUYA; FUKUTOMI KYOKO; YANAGISAWA HIROAKI; KAWASAKI TOMOMI; SAKAMOTO MASANORI,期刊：Heterocycles, 页码：627-633 , 文章类型： Article，,卷期：2009年79-1] On heating 1,2,4-triaza-1,3-dienes 1 with diphenylketene, [4+2] cycloaddition took place smoothly to afford the corresponding 1,2,4-triazin-5-one derivatives 2 in good yield. SYNTHESIS OF N-b-ACYLTRYPTAMINES AND THEIR 1-HYDROXYTRYPTAMINE DERIVATIVES AS NEW alpha(2)-BLOCKERS [作者：YAMADA KOJI; TANAKA YOSHIO; SOMEI MASANORI,期刊：Heterocycles, 页码：635-645 , 文章类型： Article，,卷期：2009年79-1] N-b-Acyl- and N-b-acyl-1-hydroxytryptamines are found to be novel and structurally simple alpha(2)-blocker for the treatment of erectile dysfunction.