- Synthesis and bioevaluation of hybrid 4-aminoquinoline triazines as a new class of antimalarial agents
[作者:Kumar, A; Srivastava, K; Kumar, SR; Puri, SK; Chauhan, PMS,期刊:Bioorganic & Medicinal Chemistry Letters, 页码:6530-6533 , 文章类型: Article,,卷期:2008年18-24]
- The emergence and rapid spread of chloroquine resistant strains of Plasmodium falciparum has dramatically reduced the chemotherapeutic options. Towards this goal, a series of new class of hybrid 4-aminoquinoline triazine...
- Coagulanolide, a withanolide from Withania coagulans fruits and antihyperglycemic activity
[作者:Maurya, R; Akanksha; Jayendra; Singh, AB; Srivastava, AK,期刊:Bioorganic & Medicinal Chemistry Letters, 页码:6534-6537 , 文章类型: Article,,卷期:2008年18-24]
- One new withanolide, (17S,20S,22R)-14 alpha,15 alpha,17 beta,20 beta-tetrahydroxy-1-oxowitha-2,5,24-trienolide) named coagulanolide (4) along with four known withanolides 1-3 and 5 have been isolated from Withania coagul...
- Origin and Radiation of the Earliest Vascular Land Plants
[作者:Steemans, P; Le Herisse, A; Melvin, J; Miller, MA; Paris, F; Verniers, J; Wellman, CH,期刊:Science, 页码:353-353 , 文章类型: Article,,卷期:2009年324-5925]
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- Optical Deconstruction of Parkinsonian Neural Circuitry
[作者:Gradinaru, V; Mogri, M; Thompson, KR; Henderson, JM; Deisseroth, K,期刊:Science, 页码:354-359 , 文章类型: Article,,卷期:2009年324-5925]
- Deep brain stimulation (DBS) is a therapeutic option for intractable neurological and psychiatric disorders, including Parkinson's disease and major depression. Because of the heterogeneity of brain tissues where electro...
- Probing Interactions Between Ultracold Fermions
[作者:Campbell, GK; Boyd, MM; Thomsen, JW; Martin, MJ; Blatt, S; Swallows, MD; Nicholson, TL; Fortier, T; Oates, CW; Diddams, SA; Lemke, ND; Naidon, P; Julienne, P; Ye, J; Ludlow, AD,期刊:Science, 页码:360-363 , 文章类型: Article,,卷期:2009年324-5925]
- At ultracold temperatures, the Pauli exclusion principle suppresses collisions between identical fermions. This has motivated the development of atomic clocks with fermionic isotopes. However, by probing an optical clock...
- A facile synthesis, antibacterial, and antitubercular studies of some piperidin-4-one and tetrahydropyridine derivatives
[作者:Aridoss, G; Amirthaganesan, S; Kumar, NA; Kim, JT; Lim, KT; Kabilan, S; Jeong, YT,期刊:Bioorganic & Medicinal Chemistry Letters, 页码:6542-6548 , 文章类型: Article,,卷期:2008年18-24]
- The raise in clinical significance of multidrug-resistant bacterial pathogens has directed us to synthesize 2,6-diarylpiperidin-4-one and Delta(3)-tetrahydropyridin-4-ol based benzimidazole and O-arylsulfonyl derivatives...
- Activation and inhibition of leukotriene A(4) hydrolase aminopeptidase activity by diphenyl ether and derivatives
[作者:Jiang, XL; Zhou, L; Wei, DG; Meng, H; Liu, Y; Lai, LH,期刊:Bioorganic & Medicinal Chemistry Letters, 页码:6549-6552 , 文章类型: Article,,卷期:2008年18-24]
- The synthesis and biological evaluation of a series of diphenyl ether derivatives were described. The compounds can either activate or inhibit the aminopeptidase activity of leukotriene A(4) hydrolase, while at the same ...
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