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  • An Access to Aza-Freidinger Lactams and E-Locked Analogs
    [作者:OTTERSBACH PHILIPP A; SCHMITZ JANINA; SCHNAKENBURG GREGOR; GUETSCHOW MICHAEL,期刊:Organic Letters, 页码:448-451 , 文章类型: Article,,卷期:2013年15-3]
  • Freidinger lactams, possessing a peptide bond configuration locked to 4 are important key elements of conformationally restricted peptidomimetics. In the present work, the C alpha Hi+1 unit has been replaced by N, leadin...
  • Copper-Catalyzed Aliphatic C-H Amination with an Amidine Moiety
    [作者:CHEN HUI; SANJAYA STEPHEN; WANG YIFENG; CHIBA SHUNSUKE,期刊:Organic Letters, 页码:212-215 , 文章类型: Article,,卷期:2013年15-1]
  • A method for amination of aliphatic C-H bonds of N-alkylamidines is described that utilizes Cu(OAc)(2) as the catalyst in the presence of Phl(OAc)(2) and K3PO4. The resulting products, dihydroimidazoles and tetrahydropyr...
  • Synthesis of Tricyclic Lactams from Heterocyclic Imines
    [作者:STALLING TIMO; MARTENS JUERGEN,期刊:Synthesis, 页码:355-364 , 文章类型: Article,,卷期:2013年45-3]
  • Starting from different heterocyclic imines, a large number of annulated tricyclic lactams were prepared in a two-step synthesis. First, methoxyamides with a phenyl ring in alpha- or beta-position were generated. Finally...