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  • MicroRNA-21 contributes to myocardial disease by stimulating MAP kinase signalling in fibroblasts
    [作者:Thum, Thomas; Gross, Carina; Fiedler, Jan; Fischer, Thomas; Kissler, Stephan; Bussen, Markus; Galuppo, Paolo; Just, Steffen; Rottbauer, Wolfgang; Frantz, Stefan; Castoldi, Mirco; Soutschek, Jurgen; Koteliansky, Victor; Rosenwald, Andreas; Basson, M. Albert; Licht, Jonathan D.; Pena, John T. R.; Rouhanifard, Sara H.; Muckenthaler, Martina U.; Tuschl, Thomas; Martin, Gail R.; Bauersachs, Johann; Engelhardt, Stefan,期刊:NATURE, 页码:980-U83 , 文章类型: 研究论文,,卷期:2008年456-7224]
  • MicroRNAs comprise a broad class of small non- coding RNAs that control expression of complementary target messenger RNAs1,2. Dysregulation of microRNAs by several mechanisms has been described in various disease states(...
  • X-ray structure of NS1 from a highly pathogenic H5N1 influenza virus
    [作者:Bornholdt, Zachary A.; Prasad, B. V. Venkataram,期刊:NATURE, 页码:985-U85 , 文章类型: 研究论文,,卷期:2008年456-7224]
  • The recent emergence of highly pathogenic avian (H5N1) influenza viruses, their epizootic and panzootic nature, and their association with lethal human infections have raised significant global health concerns(1,2). Seve...
  • Endonucleolytic RNA cleavage by a eukaryotic exosome
    [作者:Lebreton, Alice; Tomecki, Rafal; Dziembowski, Andrzej; Seraphin, Bertrand,期刊:NATURE, 页码:993-U87 , 文章类型: 研究论文,,卷期:2008年456-7224]
  • The exosome is a major eukaryotic nuclease located in both the nucleus and the cytoplasm that contributes to the processing, quality control and/ or turnover of a large number of cellular RNAs1-6. This large macromolecul...