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文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共12条记录   Ivano Bertini 1940-2012 obituary [作者：BANCI LUCIA; LUCHINAT CLAUDIO,期刊：NATURE CHEMICAL BIOLOGY, 页码：807-807 , 文章类型： Biographical-Item，,卷期：2012年8-10] Orchestrating hi-fi annotations [作者：SUTHERS PATRICK F; MARANAS COSTAS D,期刊：NATURE CHEMICAL BIOLOGY, 页码：810-811 , 文章类型： News Item，,卷期：2012年8-10] Tafazzin senses curvature [作者：GAWRISCH KLAUS,期刊：NATURE CHEMICAL BIOLOGY, 页码：811-812 , 文章类型： News Item，,卷期：2012年8-10] GhoSTly bacterial persisters [作者：VAN MELDEREN LAURENCE,期刊：NATURE CHEMICAL BIOLOGY, 页码：812-813 , 文章类型： News Item，,卷期：2012年8-10] Cytochrome P450-catalyzed L-tryptophan nitration in thaxtomin phytotoxin biosynthesis [作者：BARRY SARAH M; KERS JOHAN A; JOHNSON EVAN G; SONG LIJIANG; ASTON PHILIP R; PATEL BHUMIT; KRASNOFF STUART B; CRANE BRIAN R; GIBSON DONNA M; LORIA ROSEMARY; CHALLIS GREGORY L,期刊：NATURE CHEMICAL BIOLOGY, 页码：814-816 , 文章类型： Article，,卷期：2012年8-10] Thaxtomin phytotoxins produced by plant-pathogenic Streptomyces species contain a nitro group that is essential for phytotoxicity. The N,N'-dimethyldiketopiperazine core of thaxtomins is assembled from L-phenylalanine an... A quantitative assay for assessing the effects of DNA lesions on transcription [作者：YOU CHANGJUN; DAI XIAOXIA; YUAN BIFENG; WANG JIN; WANG JIANSHUANG; BROOKS PHILIP J; NIEDERNHOFER LAURA J; WANG YINSHENG,期刊：NATURE CHEMICAL BIOLOGY, 页码：817-822 , 文章类型： Article，,卷期：2012年8-10] Most mammalian cells in nature are quiescent but actively transcribing mRNA for normal physiological processes; thus, it is important to investigate how endogenous and exogenous DNA damage compromises transcription in ce... Cyclization of fungal nonribosomal peptides by a terminal condensation-like domain [作者：GAO XUE; HAYNES STUART W; AMES BRIAN D; WANG PENG; VIEN LINDA P; WALSH CHRISTOPHER T; TANG YI,期刊：NATURE CHEMICAL BIOLOGY, 页码：823-830 , 文章类型： Article，,卷期：2012年8-10] Cyclization of linear peptidyl precursors produced by nonribosomal peptide synthetases (NRPSs) is an important step in the biosynthesis of bioactive cyclic peptides. Whereas bacterial NRPSs use thioesterase domains to pe... Ceramide targets autophagosomes to mitochondria and induces lethal mitophagy [作者：SENTELLE R DAVID; SENKAL CAN E; JIANG WENHUI; PONNUSAMY SURIYAN; GENCER SALIH; SELVAM SHANMUGAM PANNEER; RAMSHESH VENKAT K; PETERSON YURI K; LEMASTERS JOHN J; SZULC ZDZISLAW M; BIELAWSKI JACEK; OGRETMEN BESIM,期刊：NATURE CHEMICAL BIOLOGY, 页码：831-838 , 文章类型： Article，,卷期：2012年8-10] Mechanisms by which autophagy promotes cell survival or death are unclear. We provide evidence that C-18-pyridinium ceramide treatment or endogenous C-18-ceramide generation by ceramide synthase 1 (CerS1) expression medi... Pyruvate kinase M2 activators promote tetramer formation and suppress tumorigenesis [作者：ANASTASIOU DIMITRIOS; YU YIMIN; ISRAELSEN WILLIAM J; JIANG JIANKANG; BOXER MATTHEW B; HONG BUM SOO; TEMPEL WOLFRAM; DIMOV SVETOSLAV; SHEN MIN; JHA ABHISHEK; YANG HUA; MATTAINI KATHERINE R; METALLO CHRISTIAN M; FISKE BRIAN P; COURTNEY KEVIN D; MALSTROM SCOTT; KHAN TAHSIN M; KUNG CHARLES; SKOUMBOURDIS AMANDA P; VEITH HENRIKE; SOUTHALL NOEL; WALSH MARTIN J; BRIMACOMBE KYLE R; LEISTER WILLIAM; LUNT SOPHIA Y; JOHNSON ZACHARY R; YEN KATHARINE E; KUNII KAIKO; DAVIDSON SHAWN M; CHRISTOFK HEATHER R; AUSTIN CHRISTOPHER P; INGLESE JAMES; HARRIS MARIAN H; ASARA JOHN M; STEPHANOPOULOS GREGORY; SALITURO FRANCESCO G; JIN SHENGFANG; DANG LENNY; AULD DOUGLAS S; PARK HEEWON; CANTLEY LEWIS C; THOMAS CRAIG J; HEIDEN MATTHEW G VANDER,期刊：NATURE CHEMICAL BIOLOGY, 页码：839-847 , 文章类型： Article，,卷期：2012年8-10] Cancer cells engage in a metabolic program to enhance biosynthesis and support cell proliferation. The regulatory properties of pyruvate kinase M2 (PKM2) influence altered glucose metabolism in cancer. The interaction of... Global probabilistic annotation of metabolic networks enables enzyme discovery [作者：PLATA GERMAN; FUHRER TOBIAS; HSIAO TZULIN; SAUER UWE; VITKUP DENNIS,期刊：NATURE CHEMICAL BIOLOGY, 页码：848-854 , 文章类型： Article，,卷期：2012年8-10] Annotation of organism-specific metabolic networks is one of the main challenges of systems biology. Importantly, owing to inherent uncertainty of computational annotations, predictions of biochemical function need to be... A new type V toxin-antitoxin system where mRNA for toxin GhoT is cleaved by antitoxin GhoS [作者：WANG XIAOXUE; LORD DANA M; CHENG HSINYAO; OSBOURNE DEVON O; HONG SEOK HOON; SANCHEZTORRES VIVIANA; QUIROGA CECILIA; ZHENG KEVIN; HERRMANN TORSTEN; PETI WOLFGANG; BENEDIK MICHAEL J; PAGE REBECCA; WOOD THOMAS K,期刊：NATURE CHEMICAL BIOLOGY, 页码：855-861 , 文章类型： Article，,卷期：2012年8-10] Among bacterial toxin-antitoxin systems, to date no antitoxin has been identified that functions by cleaving toxin mRNA. Here we show that YjdO (renamed GhoT) is a membrane lytic peptide that causes ghost cell formation ... The physical state of lipid substrates provides transacylation specificity for tafazzin [作者：SCHLAME MICHAEL; ACEHAN DEVRIM; BERNO BOB; XU YANG; VALVO SALVATORE; REN MINDONG; STOKES DAVID L; EPAND RICHARD M,期刊：NATURE CHEMICAL BIOLOGY, 页码：862-869 , 文章类型： Article，,卷期：2012年8-10] Cardiolipin is a mitochondrial phospholipid with a characteristic acyl chain composition that depends on the function of tafazzin, a phospholipid-lysophospholipid transacylase, although the enzyme itself lacks acyl speci...