A highly selective oxidative palladium(II)-catalyzed (Wacker-type) cyclization of readily available allylic tosylcarbamates is reported. This operationally simple catalytic reaction furnishes tosyl-protected vinyl-oxazol...
Direct C?H functionalization of various enamides and enecarbamates was realized through visible-light photoredox catalyzed reactions. Under the optimized conditions using [Ir(ppy)2(dtbbpy)PF6] as photocatalyst in combina...
This paper presents a theoretical study of electrochemical affinity biosensors for the detection of DNA/protein that utilize nanoparticle labels for signal amplification. This study analyzes the effects of binding and ma...
Novel cycloruthenated complexes 2?ac, 4?ac, and 6?a,?b based on heteroaromatic cores have been synthesized by reaction of a series of heterocycle-based imines with [{RuCl(?6-p-cymene)}2(mu?Cl)2] and Cu(OAc)2. This approa...
A new type of chiral sulfonium salts that are characterized by a bicyclic system has been designed and synthesized from a-amino acids. Their corresponding ylides, which were prepared by basic treatment of the sulfonium s...
A formal total synthesis of the 20-membered marine macrolide, palmerolide A from chiral pool tartaric acid is described. Elaboration of a ?-hydroxy amide, which is derived from the desymmetrization of tartaric acid amide...
The combination of a fluorine atom and a cyclopropane ring, which both possess unique structural and chemical features, can generate new relevant building blocks for the discovery of efficient fluorinated biologically ac...