- Depression during Pregnancy
[作者:Stewart, DE,期刊:New England Journal of Medicine, 页码:1605-1611 , 文章类型: Article,,卷期:2011年365-17]
- A 24-year-old married woman presents with a 1-month history of diminished concentration and interest, insomnia, fatigue, tearfulness, and depressed mood. She is 10 weeks pregnant, stopped working 3 weeks ago, and mostly ...
- Small-Airway Obstruction and Emphysema in Chronic Obstructive Pulmonary Disease
[作者:McDonough, JE; Yuan, R; Suzuki, M; Seyednejad, N; Elliott, WM; Sanchez, PG; Wright, AC; Gefter, WB; Litzky, L; Coxson, HO; Pare, PD; Sin, DD; Pierce, RA; Woods, JC; McWilliams, AM; Mayo, JR; Lam, SC; Cooper, JD; Hogg, JC,期刊:New England Journal of Medicine, 页码:1567-1575 , 文章类型: Article,,卷期:2011年365-17]
- BACKGROUNDThe major sites of obstruction in chronic obstructive pulmonary disease (COPD) are small airways (<2 mm in diameter). We wanted to determine whether there was a relationship between small-airway obstruction and...
- HPV Vaccine against Anal HPV Infection and Anal Intraepithelial Neoplasia
[作者:Palefsky, JM; Giuliano, AR; Goldstone, S; Moreira, ED; Aranda, C; Jessen, H; Hillman, R; Ferris, D; Coutlee, F; Stoler, MH; Marshall, JB; Radley, D; Vuocolo, S; Haupt, RM; Guris, D; Garner, EIO,期刊:New England Journal of Medicine, 页码:1576-1585 , 文章类型: Article,,卷期:2011年365-17]
- BACKGROUNDThe rate of anal cancer is increasing among both women and men, particularly men who have sex with men. Caused by infection with human papillomavirus (HPV), primarily HPV type 16 or 18, anal cancer is preceded ...
- A 52-Week Trial Comparing Briakinumab with Methotrexate in Patients with Psoriasis
[作者:Reich, K; Langley, RG; Papp, KA; Ortonne, JP; Unnebrink, K; Kaul, M; Valdes, JM,期刊:New England Journal of Medicine, 页码:1586-1596 , 文章类型: Article,,卷期:2011年365-17]
- BACKGROUNDBriakinumab is a monoclonal antibody against the p40 molecule shared by interleukin-12 and interleukin-23, which is overexpressed in psoriatic skin lesions. We assessed the efficacy and safety of briakinumab as...
- Long-Term Persistence of Hormonal Adaptations to Weight Loss
[作者:Sumithran, P; Prendergast, LA; Delbridge, E; Purcell, K; Shulkes, A; Kriketos, A; Proietto, J,期刊:New England Journal of Medicine, 页码:1597-1604 , 文章类型: Article,,卷期:2011年365-17]
- BACKGROUNDAfter weight loss, changes in the circulating levels of several peripheral hormones involved in the homeostatic regulation of body weight occur. Whether these changes are transient or persist over time may be i...
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