- Sox2(+) Adult Stem and Progenitor Cells Are Important for Tissue Regeneration and Survival of Mice
[作者：Arnold, K; Sarkar, A; Yram, MA; Polo, JM; Bronson, R; Sengupta, S; Seandle, M; Geijsen, N; Hochedlinger, K,期刊：Cell Stem Cell, 页码：317-329 , 文章类型： Article，,卷期：2011年9-4]
- The transcription factor Sox2 maintains the pluripotency of early embryonic cells and regulates the formation of several epithelia during fetal development. Whether Sox2 continues to play a role in adult tissues remains ...
- Cripto Regulates Hematopoietic Stem Cells as a Hypoxic-Niche-Related Factor through Cell Surface Receptor GRP78
[作者：Miharada, K; Karlsson, G; Rehn, M; Rorby, E; Siva, K; Cammenga, J; Karlsson, S,期刊：Cell Stem Cell, 页码：330-344 , 文章类型： Article，,卷期：2011年9-4]
- Hematopoietic stem cells (HSCs) are maintained in hypoxic niches in endosteal regions of bones. Here we demonstrate that Cripto and its receptor GRP78 are important regulators of HSCs in the niche. Flow cytometry analyse...
- Canonical Wnt Signaling Regulates Hematopoiesis in a Dosage-Dependent Fashion
[作者：Luis, TC; Naber, BAE; Roozen, PPC; Brugman, MH; de Haas, EFE; Ghazvini, M; Fibbe, WE; van Dongen, JJM; Fodde, R; Staal, FJT,期刊：Cell Stem Cell, 页码：345-356 , 文章类型： Article，,卷期：2011年9-4]
- Canonical Wnt signaling has been implicated in the regulation of hematopoiesis. By employing a Wnt-reporter mouse, we observed that Wnt signaling is differentially activated during hematopoiesis, suggesting an important ...
- Distinct Types of Tumor-Initiating Cells Form Human Colon Cancer Tumors and Metastases
[作者：Dieter, SM; Ball, CR; Hoffmann, CM; Nowrouzi, A; Herbst, F; Zavidij, O; Abel, U; Arens, A; Weichert, W; Brand, K; Koch, M; Weitz, J; Schmidt, M; von Kalle, C; Glimm, H,期刊：Cell Stem Cell, 页码：357-365 , 文章类型： Article，,卷期：2011年9-4]
- Human colon cancer harbors a small subfraction of tumor-initiating cells (TICs) that is assumed to be a functionally homogeneous stem-cell-like population driving tumor maintenance and metastasis formation. We found unex...
- Genome Sequencing of Mouse Induced Pluripotent Stem Cells Reveals Retroelement Stability and Infrequent DNA Rearrangement during Reprogramming
[作者：Quinlan, AR; Boland, MJ; Leibowitz, ML; Shumilina, S; Pehrson, SM; Baldwin, KK; Hall, IM,期刊：Cell Stem Cell, 页码：366-373 , 文章类型： Article，,卷期：2011年9-4]
- The biomedical utility of induced pluripotent stem cells (iPSCs) will be diminished if most iPSC lines harbor deleterious genetic mutations. Recent micro-array studies have shown that human iPSCs carry elevated levels of...
- Direct Lineage Conversion of Terminally Differentiated Hepatocytes to Functional Neurons
[作者：Marro, S; Pang, ZPP; Yang, N; Tsai, MC; Qu, K; Chang, HY; Sudhof, TC; Wernig, M,期刊：Cell Stem Cell, 页码：374-382 , 文章类型： Article，,卷期：2011年9-4]
- Several recent studies have showed that mouse and human fibroblasts can be directly reprogrammed into induced neuronal (iN) cells, bypassing a pluripotent intermediate state. However, fibroblasts represent heterogeneous ...
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