- Chemical-Biological Studies of Subcellular Organization in Bacteria
[作者:Foss, MH; Eun, YJ; Weibel, DB,期刊:Biochemistry, 页码:7719-7734 , 文章类型: Article,,卷期:2011年50-36]
- The subcellular organization of biological molecules is a critical determinant of many bacterial processes, including growth, replication of the genome, and division, yet the details of many mechanisms that control intra...
- Enhanced Specificity of the Viral Suppressor of RNA Silencing Protein p19 toward Sequestering of Human MicroRNA-122
[作者:Cheng, J; Danielson, DC; Nasheri, N; Singaravelu, R; Pezacki, JP,期刊:Biochemistry, 页码:7745-7755 , 文章类型: Article,,卷期:2011年50-36]
- Tombusviruses express a 19 kDa protein (p19) that, as a dimeric protein, suppresses the RNAs silencing pathway during infection by binding short-interfering RNA (siRNA) and preventing their association with the RNA-induc...
- Biosynthesis of Unnatural Bacteriochlorophyll c Derivatives Esterified with alpha,omega-Diols in the Green Sulfur Photosynthetic Bacterium Chlorobaculum tepidum
[作者:Nishimori, R; Mizoguchi, T; Tamiaki, H; Kashimura, S; Saga, Y,期刊:Biochemistry, 页码:7756-7764 , 文章类型: Article,,卷期:2011年50-36]
- Unnatural bacteriochlorophyll (BChl) c derivatives possessing a hydroxy group at the terminus of a hydrocarbon chain at the 17-propionate were biosynthesized in the green sulfur photosynthetic bacterium Chlorobaculum tep...
- Cell Death Induced by the Jak2 Inhibitor, G6, Correlates with Cleavage of Vimentin Filaments
[作者:Majumder, A; Kirabo, A; Karrupiah, K; Tsuda, S; Caldwell-Busby, J; Cardounel, AJ; Keseru, GM; Sayeski, PP,期刊:Biochemistry, 页码:7774-7786 , 文章类型: Article,,卷期:2011年50-36]
- Hyperkinetic Jak2 tyrosine kinase signaling has been implicated in several human diseases including leukemia, lymphoma, myeloma, and the myeloproliferative neoplasms. Using structure-based virtual screening, we previousl...
- Thrombospondin-1 and Angiotensin II Inhibit Soluble Guanylyl Cyclase through an Increase in Intracellular Calcium Concentration
[作者:Ramanathan, S; Mazzalupo, S; Boitano, S; Montfort, WR,期刊:Biochemistry, 页码:7787-7799 , 文章类型: Article,,卷期:2011年50-36]
- Nitric oxide (NO) regulates cardiovascular hemostasis by binding to soluble guanylyl cyclase (sGC), leading to cGMP production, reduced cytosolic calcium concentration ([Ca(2+)](i)), and vasorelaxation. Thrombospondin-1 ...
- Structural Basis of Substrate Recognition in Human Nicotinamide N-Methyltransferase
[作者:Peng, Y; Sartini, D; Pozzi, V; Wilk, D; Emanuelli, M; Yee, VC,期刊:Biochemistry, 页码:7800-7808 , 文章类型: Article,,卷期:2011年50-36]
- Nicotinamide N-methyltransferase (NNMT) catalyzes the N-methylation of nicotinamide, pyridines, and other analogues using S-adenosyl-L-methionine as donor. NNMT plays a significant role in the regulation of metabolic pat...
- Comprehensive Structural Analysis of Mutant Nucleosomes Containing Lysine to Glutamine (KQ) Substitutions in the H3 and H4 Histone-Fold Domains
[作者:Iwasaki, W; Tachiwana, H; Kawaguchi, K; Shibata, T; Kagawa, W; Kurumizaka, H,期刊:Biochemistry, 页码:7822-7832 , 文章类型: Article,,卷期:2011年50-36]
- Post-translational modifications (PTMs) of histones play important roles in regulating the structure and function of chromatin in eukaryotes. Although histone PTMs were considered to mainly occur at the N-terminal tails ...
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