- Mechanism of Bacterial Transcription Initiation: RNA Polymerase - Promoter Binding, Isomerization to Initiation-Competent Open Complexes, and Initiation of RNA Synthesis
[作者:Saecker, RM; Record, MT; Dehaseth, PL,期刊:Journal of Molecular Biology, 页码:754-771 , 文章类型: Review,,卷期:2011年412-5]
- Initiation of RNA synthesis from DNA templates by RNA polymerase (RNAP) is a multi-step process, in which initial recognition of promoter DNA by RNAP triggers a series of conformational changes in both RNAP and promoter ...
- Reprint of: Inhibition of Escherichia coil RNAp by T7 Gp2 protein: Role of Negatively Charged Strip of Amino Acid Residues in Gp2
[作者:Sheppard, C; Camara, B; Shadrin, A; Akulenko, N; Liu, MH; Baldwin, G; Severinov, K; Cota, E; Matthews, S; Wigneshweraraj, SR,期刊:Journal of Molecular Biology, 页码:832-841 , 文章类型: Article,,卷期:2011年412-5]
- Gp2, a 7 kDa protein encoded by T7 bacteriophage, is a potent inhibitor of Escherichia coli RNA polymerase (RNAp), the enzyme responsible for transcription of all bacterial genes and early viral genes. A prominent featur...
- The Antibacterial Threaded-lasso Peptide Capistruin Inhibits Bacterial RNA Polymerase
[作者:Kuznedelov, K; Semenova, E; Knappe, TA; Mukhamedyarov, D; Srivastava, A; Chatterjee, S; Ebright, RH; Marahiel, MA; Severinov, K,期刊:Journal of Molecular Biology, 页码:842-848 , 文章类型: Article,,卷期:2011年412-5]
- Capistruin, a ribosomally synthesized, post-translationally modified peptide produced by Burkholderia thailandensis E264, efficiently inhibits growth of Burkholderia and closely related Pseudomonas strains. The functiona...
- Helix 12 Dynamics and Thyroid Hormone Receptor Activity: Experimental and Molecular Dynamics Studies of Ile280 Mutants
[作者:Souza, PCT; Barra, GB; Velasco, LFR; Ribeiro, ICJ; Simeoni, LA; Togashi, M; Webb, P; Neves, FAR; Skaf, MS; Martinez, L; Polikarpov, I,期刊:Journal of Molecular Biology, 页码:882-893 , 文章类型: Article,,卷期:2011年412-5]
- Nuclear hormone receptors (NRs) form a family of transcription factors that mediate cellular responses initiated by hormone binding. It is generally recognized that the structure and dynamics of the C-terminal helix 12 (...
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