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  • Efficacy of a Tyrosine Kinase Inhibitor in Idiopathic Pulmonary Fibrosis
    [作者:Richeldi, L; Costabel, U; Selman, M; Kim, DS; Hansell, DM; Nicholson, AG; Brown, KK; Flaherty, KR; Noble, PW; Raghu, G; Brun, M; Gupta, A; Juhel, N; Kluglich, M; du Bois, RM,期刊:New England Journal of Medicine, 页码:1079-1087 , 文章类型: Article,,卷期:2011年365-12]
  • Background Idiopathic pulmonary fibrosis is a progressive lung disease with a high mortality rate. Because the signaling pathways activated by several tyrosine kinase receptors have been shown to be involved in lung fibr...
  • Lebrikizumab Treatment in Adults with Asthma
    [作者:Corren, J; Lemanske, RF; Hanania, NA; Korenblat, PE; Parsey, MV; Arron, JR; Harris, JM; Scheerens, H; Wu, LC; Su, Z; Mosesova, S; Eisner, MD; Bohen, SP; Matthews, JG,期刊:New England Journal of Medicine, 页码:1088-1098 , 文章类型: Article,,卷期:2011年365-12]
  • Background Many patients with asthma have uncontrolled disease despite treatment with inhaled glucocorticoids. One potential cause of the variability in response to treatment is heterogeneity in the role of interleukin-1...