- Adjuvant Trastuzumab in HER2-Positive Breast Cancer
[作者:Slamon, D; Eiermann, W; Robert, N; Pienkowski, T; Martin, M; Press, M; Mackey, J; Glaspy, J; Chan, A; Pawlicki, M; Tamas, P; Valero, V; Liu, MC; Sauter, G; von Minckwitz, G; Visco, F; Bee, V; Buyse, M; Bendahmane, B; Tabah-Fisch, I; Lindsay, MA; Riva, A; Crown, J,期刊:New England Journal of Medicine, 页码:1273-1283 , 文章类型: Article,,卷期:2011年365-14]
- BACKGROUND Trastuzumab improves survival in the adjuvant treatment of HER-positive breast cancer, although combined therapy with anthracycline-based regimens has been associated with cardiac toxicity. We wanted to evalua...
- Randomized Trial of Oral Teriflunomide for Relapsing Multiple Sclerosis
[作者:O'Connor, P; Wolinsky, JS; Confavreux, C; Comi, G; Kappos, L; Olsson, TP; Benzerdjeb, H; Truffinet, P; Wang, L; Miller, A; Freedman, MS,期刊:New England Journal of Medicine, 页码:1293-1303 , 文章类型: Article,,卷期:2011年365-14]
- BACKGROUND Teriflunomide is a new oral disease-modifying therapy for relapsing forms of multiple sclerosis. METHODS We concluded a randomized trial involving 1088 patients with multiple sclerosis, 18 to 55 years of age, ...
- Oral Acyclovir Suppression and Neurodevelopment after Neonatal Herpes
[作者:Kimberlin, DW; Whitley, RJ; Wan, W; Powell, DA; Storch, G; Ahmed, A; Palmer, A; Sanchez, PJ; Jacobs, RF; Bradley, JS; Robinson, JL; Shelton, M; Dennehy, PH; Leach, C; Rathore, M; Abughali, N; Wright, P; Frenkel, LM; Brady, RC; Van Dyke, R; Weiner, LB; Guzman-Cottrill, J; McCarthy, CA; Griffin, J; Jester, P; Parker, M; Lakeman, FD; Kuo, HC; Lee, CH; Cloud, GA,期刊:New England Journal of Medicine, 页码:1284-1292 , 文章类型: Article,,卷期:2011年365-14]
- BACKGROUND Poor neurodevelopmental outcomes and recurrences of cutaneous lesions remain unacceptably frequent among survivors of neonatal herpes simplex virus (HSV) disease. METHODS We enrolled neonates with HSV disease ...
- Adverse Health Outcomes in Women Exposed In Utero to Diethylstilbestrol
[作者:Hoover, RN; Hyer, M; Pfeiffer, RM; Adam, E; Bond, B; Cheville, AL; Colton, T; Hartge, P; Hatch, EE; Herbst, AL; Karlan, BY; Kaufman, R; Noller, KL; Palmer, JR; Robboy, SJ; Saal, RC; Strohsnitter, W; Titus-Ernstoff, L; Troisi, R,期刊:New England Journal of Medicine, 页码:1304-1314 , 文章类型: Article,,卷期:2011年365-14]
- BACKGROUND Before 1971, several million women were exposed in utero to diethylstilbestrol (DES) given to their mothers to prevent pregnancy complications. Several adverse outcomes have been linked to such exposure, but t...
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