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文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共13条记录   Adipokine ganglioside GM2 activator protein stimulates insulin secretion [作者：Higashi, K; Kubo, H; Watanabe, H; Fujimori, K; Mikami, T; Kaneko, H,期刊：FEBS Letters, 页码：2587-2591 , 文章类型： Article，,卷期：2011年585-16] Recently, we identified ganglioside GM2 activator protein (GM2AP) as a novel adipokine, and revealed that treatment of cultured cells with GM2AP impairs insulin signal transduction. The aim of this study was to examine t... MicroRNA-19b downregulates insulin 1 through targeting transcription factor NeuroD1 [作者：Zhang, ZW; Zhang, LQ; Ding, L; Wang, F; Sun, YJ; An, Y; Zhao, Y; Li, YH; Teng, CB,期刊：FEBS Letters, 页码：2592-2598 , 文章类型： Article，,卷期：2011年585-16] MiR-17-92 cluster miRNAs are disclosed to contribute to the development of multiple organs and tumorigenesis, but their roles in pancreas development remains unclear. In this study, we found that miR-19b, a member of miR... Ligand entry pathways in the ligand binding domain of PPAR gamma receptor [作者：Aci-Seche, S; Genest, M; Garnier, N,期刊：FEBS Letters, 页码：2599-2603 , 文章类型： Article，,卷期：2011年585-16] To address the question of ligand entry process, we report targeted molecular dynamics simulations of the entry of the flexible ionic ligand GW0072 in the ligand binding domain of the nuclear receptor PPAR gamma. Startin... Functional analysis of metal tolerance proteins isolated from Zn/Cd hyperaccumulating ecotype and non-hyperaccumulating ecotype of Sedum alfredii Hance [作者：Zhang, M; Senoura, T; Yang, XE; Nishizawa, NK,期刊：FEBS Letters, 页码：2604-2609 , 文章类型： Article，,卷期：2011年585-16] The Zn/Cd hyperaccumulating ecotype (HE) of Sedum alfredii Hance can accumulate 24- and 28-fold higher leaf and stem Zn concentrations when compared with the non-hyperaccumulating ecotype (NHE) of Sedum. Heterologous exp... A non-coding transcript of nephronectin promotes osteoblast differentiation by modulating microRNA functions [作者：Lee, SC; Fang, L; Wang, CH; Kahai, S; Deng, ZQ; Yang, BB,期刊：FEBS Letters, 页码：2610-2616 , 文章类型： Article，,卷期：2011年585-16] We investigated the roles of the non-coding transcripts and found that expression of a fragment containing the 3'-untranslated region (3'-UTR) of nephronectin in osteoblast progenitor cells MC3T3-E1 promoted cell differe... Crystal structure of human MTH1 and the 8-oxo-dGMP product complex [作者：Svensson, LM; Jemth, AS; Desroses, M; Loseva, O; Helleday, T; Hogbom, M; Stenmark, P,期刊：FEBS Letters, 页码：2617-2621 , 文章类型： Article，,卷期：2011年585-16] MTH1 hydrolyzes oxidized nucleotide triphosphates, thereby preventing them from being incorporated into DNA. We here present the structures of human MTH1 (1.9 angstrom) and its complex with the product 8-oxo-dGMP (1.8 an... Effect of solution viscosity on intraprotein electron transfer between the FMN and heme domains in inducible nitric oxide synthase [作者：Li, WB; Fan, WH; Elmore, BO; Feng, CJ,期刊：FEBS Letters, 页码：2622-2626 , 文章类型： Article，,卷期：2011年585-16] The FMN-heme intraprotein electron transfer (IET) kinetics in a human inducible NOS (iNOS) oxygenase/FMN construct were determined by laser flash photolysis as a function of solution viscosity (1.0-3.0 cP). In the presen... Antiviral effects of human microRNAs and conservation of their target sites [作者：Russo, A; Potenza, N,期刊：FEBS Letters, 页码：2551-2555 , 文章类型： Review，,卷期：2011年585-16] MicroRNAs are small non-coding RNAs that modulate gene expression at post-transcriptional level, playing a crucial role in cell differentiation and development. Recently, some reports have shown that a limited number of ... Evidence for the association of the human regulatory protein Ki-1/57 with the translational machinery [作者：Goncalves, KD; Bressan, GC; Saito, A; Morello, LG; Zanchin, NIT; Kobarg, J,期刊：FEBS Letters, 页码：2556-2560 , 文章类型： Article，,卷期：2011年585-16] Ki-1/57 is a cytoplasmic and nuclear protein of 57 kDa first identified in malignant cells from Hodgkin's lymphoma. Based on yeast-two hybrid protein interaction we found out that Ki-1/57 interacts with adaptor protein R... Structure and nucleotide specificity of Staphylococcus aureus dihydrodipicolinate reductase (DapB) [作者：Girish, TS; Navratna, V; Gopal, B,期刊：FEBS Letters, 页码：2561-2567 , 文章类型： Article，,卷期：2011年585-16] Lysine biosynthesis proceeds by the nucleotide-dependent reduction of dihydrodipicolinate (DHDP) to tetrahydrodipicolinate (THDP) by dihydrodipicolinate reductase (DHDPR). The S. aureus DHDPR structure reveals different ... Mutant ubiquitin (UBB+1) associated with neurodegenerative disorders is hydrolyzed by ubiquitin C-terminal hydrolase L3 (UCH-L3) [作者：Dennissen, FJA; Kholod, N; Hermes, DJHP; Kemmerling, N; Steinbusch, HWM; Dantuma, NP; van Leeuwen, FW,期刊：FEBS Letters, 页码：2568-2574 , 文章类型： Article，,卷期：2011年585-16] Mutant ubiquitin (UBB+1) accumulates in the hallmarks of tauopathies and polyglutamine diseases. We show that the deubiquitinating enzyme YUH1 of Saccharomyces cerevisiae and its mouse and human ortholog UCH-L3 are able ... RNA binding property and RNA chaperone activity of dengue virus core protein and other viral RNA-interacting proteins [作者：Pong, WL; Huang, ZS; Teoh, PG; Wang, CC; Wu, HN,期刊：FEBS Letters, 页码：2575-2581 , 文章类型： Article，,卷期：2011年585-16] In this study we showed that the dengue virus (DENV) core protein forms a dimer with an alpha-helix-rich structure, binds RNA and facilitates the strand annealing process. To assess the RNA chaperone activity of this cor... Turnover of ATP synthase subunits in F-1-depleted HeLa and yeast cells [作者：Rak, M; McStay, GP; Fujikawa, M; Yoshida, M; Manfredi, G; Tzagoloff, A,期刊：FEBS Letters, 页码：2582-2586 , 文章类型： Article，,卷期：2011年585-16] Mitochondrial translation of the Saccharomyces cerevisiae Atp6p subunit of F-1-F-0 ATP synthase is regulated by the F-1 ATPase. Here we show normal expression of Atp6p in HeLa cells depleted of the F-1 beta subunit. Inst...