- Cooperative Transcriptional Activation by Klf4, Meis2, and Pbx1
[作者：Bjerke, GA; Hyman-Walsh, C; Wotton, D,期刊：Molecular and Cellular Biology, 页码：3723-3733 , 文章类型： Article，,卷期：2011年31-18]
- The Kruppel-like factor Klf4 is implicated in tumorigenesis and maintaining stem cell pluripotency, and Klf4 can both activate and repress gene expression. We show that the Pbx1 and Meis2 homeodomain proteins interact wi...
- The Tightly Controlled Deubiquitination Activity of the Human SAGA Complex Differentially Modifies Distinct Gene Regulatory Elements
[作者：Lang, G; Bonnet, J; Umlauf, D; Karmodiya, K; Koffler, J; Stierle, M; Devys, D; Tora, L,期刊：Molecular and Cellular Biology, 页码：3734-3744 , 文章类型： Article，,卷期：2011年31-18]
- The multisubunit SAGA coactivator complex facilitates access of general transcription factors to DNA through histone acetylation mediated by GCN5. USP22 (ubiquitin-specific protease 22) was recently described as a subuni...
- Requirement of FADD, NEMO, and BAX/BAK for Aberrant Mitochondrial Function in Tumor Necrosis Factor Alpha-Induced Necrosis
[作者：Irrinki, KM; Mallilankaraman, K; Thapa, RJ; Chandramoorthy, HC; Smith, FJ; Jog, NR; Gandhirajan, RK; Kelsen, SG; Houser, SR; May, MJ; Balachandran, S; Madesh, M,期刊：Molecular and Cellular Biology, 页码：3745-3758 , 文章类型： Article，,卷期：2011年31-18]
- Necroptosis represents a form of alternative programmed cell death that is dependent on the kinase RIP1. RIP1-dependent necroptotic death manifests as increased reactive oxygen species (ROS) production in mitochondria an...
- Bioluminescence Imaging Captures the Expression and Dynamics of Endogenous p21 Promoter Activity in Living Mice and Intact Cells
[作者：Tinkum, KL; Marpegan, L; White, LS; Sun, JW; Herzog, ED; Piwnica-Worms, D; Piwnica-Worms, H,期刊：Molecular and Cellular Biology, 页码：3759-3772 , 文章类型： Article，,卷期：2011年31-18]
- To interrogate endogenous p21(WAF1/CIP1) (p21) promoter activity under basal conditions and in response to various forms of stress, knock-in imaging reporter mice in which expression of firefly luciferase (FLuc) was plac...
- Translational Control of TOP2A Influences Doxorubicin Efficacy
[作者：Srikantan, S; Abdelmohsen, K; Lee, EK; Tominaga, K; Subaran, SS; Kuwano, Y; Kulshrestha, R; Panchakshari, R; Kim, HH; Yang, XL; Martindale, JL; Marasa, BS; Kim, MM; Wersto, RP; Indig, FE; Chowdhury, D; Gorospe, M,期刊：Molecular and Cellular Biology, 页码：3790-3801 , 文章类型： Article，,卷期：2011年31-18]
- The cellular abundance of topoisomerase II alpha (TOP2A) critically maintains DNA topology after replication and determines the efficacy of TOP2 inhibitors in chemotherapy. Here, we report that the RNA-binding protein Hu...
- DDX60, a DEXD/H Box Helicase, Is a Novel Antiviral Factor Promoting RIG-I-Like Receptor-Mediated Signaling
[作者：Miyashita, M; Oshiumi, H; Matsumoto, M; Seya, T,期刊：Molecular and Cellular Biology, 页码：3802-3819 , 文章类型： Article，,卷期：2011年31-18]
- The cytoplasmic viral RNA sensors RIG-I and MDA5 are important for the production of type I interferon and other inflammatory cytokines. DDX60 is an uncharacterized DEXD/H box RNA helicase similar to Saccharomyces cerevi...
- Stomatin-Like Protein 2 Binds Cardiolipin and Regulates Mitochondrial Biogenesis and Function
[作者：Christie, DA; Lemke, CD; Elias, IM; Chau, LA; Kirchhof, MG; Li, B; Ball, EH; Dunn, SD; Hatch, GM; Madrenas, J,期刊：Molecular and Cellular Biology, 页码：3845-3856 , 文章类型： Article，,卷期：2011年31-18]
- Stomatin-like protein 2 (SLP-2) is a widely expressed mitochondrial inner membrane protein of unknown function. Here we show that human SLP-2 interacts with prohibitin-1 and -2 and binds to the mitochondrial membrane pho...
- The Midblastula Transition Defines the Onset of Y RNA-Dependent DNA Replication in Xenopus laevis
[作者：Collart, C; Christov, CP; Smith, JC; Krude, T,期刊：Molecular and Cellular Biology, 页码：3857-3870 , 文章类型： Article，,卷期：2011年31-18]
- Noncoding Y RNAs are essential for the initiation of chromosomal DNA replication in mammalian cell extracts, but their role in this process during early vertebrate development is unknown. Here, we use antisense morpholin...
- Key Functional Regions in the Histone Variant H2A.Z C-Terminal Docking Domain
[作者：Wang, AY; Aristizabal, MJ; Ryan, C; Krogan, NJ; Kobor, MS,期刊：Molecular and Cellular Biology, 页码：3871-3884 , 文章类型： Article，,卷期：2011年31-18]
- The incorporation of histone variants into nucleosomes represents one way of altering the chromatin structure to accommodate diverse functions. Histone variant H2A.Z has specific roles in gene regulation, heterochromatin...
- Hypoxia-Inducible Factor 1 Is Activated by Dysregulated Cyclin E during Mammary Epithelial Morphogenesis
[作者：Sengupta, T; Abraham, G; Xu, YF; Clurman, BE; Minella, AC,期刊：Molecular and Cellular Biology, 页码：3885-3895 , 文章类型： Article，,卷期：2011年31-18]
- Increased cyclin E expression has been identified in human tumors of diverse histologies, and in studies of primary breast cancers, high cyclin E is associated with poor prognosis. We have studied dysregulated cyclin E i...
- Specific Contribution of the Erythropoietin Gene 3 ' Enhancer to Hepatic Erythropoiesis after Late Embryonic Stages
[作者：Suzuki, N; Obara, N; Pan, XQ; Watanabe, M; Jishage, KI; Minegishi, N; Yamamoto, M,期刊：Molecular and Cellular Biology, 页码：3896-3905 , 文章类型： Article，,卷期：2011年31-18]
- Erythropoietin (Epo) is secreted from the liver and kidney, where Epo production is strictly regulated at the transcriptional level in a hypoxia- and/or anemia-inducible manner. Here, we examined the in vivo function of ...
- p300-Dependent ATF5 Acetylation Is Essential for Egr-1 Gene Activation and Cell Proliferation and Survival
[作者：Liu, DX; Qian, DM; Wang, B; Yang, JM; Lu, ZM,期刊：Molecular and Cellular Biology, 页码：3906-3916 , 文章类型： Article，,卷期：2011年31-18]
- ATF5 has been shown to be a critical regulator of cell proliferation and survival; however, the underlying mechanism remains largely unknown. We demonstrate here that ATF5 interacts with the transcriptional coactivator p...
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