- Radiation enhances long-term metastasis potential of residual hepatocellular carcinoma in nude mice through TMPRSS4-induced epithelial-mesenchymal transition
[作者:Li, T; Zeng, ZC; Wang, L; Qiu, SJ; Zhou, JW; Zhi, XT; Yu, HH; Tang, ZY,期刊:Cancer gene therapy, 页码:617-626 , 文章类型: Article,,卷期:2011年18-9]
- Recurrence and metastasis are frequently observed after radiotherapy for hepatocellular carcinoma (HCC), although upregulation of matrix metalloproteinases (MMPs) and vascular endothelial growth factor (VEGF) induced by ...
- Enhanced tumor suppression by an ING4/IL-24 bicistronic adenovirus-mediated gene cotransfer in human non-small cell lung cancer cells
[作者:Zhu, Y; Lv, H; Xie, Y; Sheng, W; Xiang, J; Yang, J,期刊:Cancer gene therapy, 页码:627-636 , 文章类型: Article,,卷期:2011年18-9]
- ING4 as a member of inhibitor of growth (ING) tumor suppressor family has potent inhibitory effects on a variety of tumors. Interleukin-24 (IL-24), a cytokine-tumor suppressor, also shows broad-spectrum and tumor-specifi...
- Baculovirus vectors for antiangiogenesis-based cancer gene therapy
[作者:Luo, WY; Shih, YS; Lo, WH; Chen, HR; Wang, SC; Wang, CH; Chien, CH; Chiang, CS; Chuang, YJ; Hu, YC,期刊:Cancer gene therapy, 页码:637-645 , 文章类型: Article,,卷期:2011年18-9]
- Baculovirus is an insect virus that is non-pathogenic to humans and has emerged as a promising gene therapy vector. Since solid tumor growth/metastasis critically relies on angiogenesis and hEA, a fusion protein comprisi...
- Screening siRNAs targeting a novel gene (HA117) and the development of a derivative recombinant adenovirus delivery system
[作者:Zheng, GH; Luo, Q; Jin, XQ; Guo, YX; Xu, YH,期刊:Cancer gene therapy, 页码:655-662 , 文章类型: Article,,卷期:2011年18-9]
- A novel gene, HA117, was discovered in our previous work. Using the pSOS-HUS vector method which we designed at previous study, we screened for small interfering RNAs (siRNAs) that targeted HA117. The pSOS-HUS siRNA scre...
- Therapeutic effectiveness of intratumorally delivered dendritic cells engineered to express the pro-inflammatory cytokine, interleukin (IL)-32
[作者:Qu, Y; Taylor, JL; Bose, A; Storkus, WJ,期刊:Cancer gene therapy, 页码:663-673 , 文章类型: Article,,卷期:2011年18-9]
- Interleukin-32 (IL-32) is a pro-inflammatory cytokine conditionally produced by T cells, natural killer (NK) cells, monocytes, epithelial cells and keratinocytes, which has an important role in host resistance against in...
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