- Herbal Medicines and Nutraceuticals for Diabetic Vascular Complications: Mechanisms of Action and Bioactive Phytochemicals
[作者:Omar, EA; Kam, A; Alqahtani, A; Li, KM; Razmovski-Naumovski, V; Nammi, S; Chan, K; Roufogalis, BD; Li, GQ,期刊:Current Pharmaceutical Design, 页码:3776-3807 , 文章类型: Review,,卷期:2010年16-34]
- Diabetes is one of the most prevalent chronic diseases throughout the world. The majority of its complications arise from vascular-related inflammation apparently initiated by endothelial cell injury. One cause of this i...
- Chronic Hepatitis C, Insulin Resistance and Vascular Disease
[作者:Trpkovic, A; Stokic, E; Radak, D; Gluvic, Z; Haidara, M; Mikhailidis, DP; Isenovic, ER,期刊:Current Pharmaceutical Design, 页码:3823-3829 , 文章类型: Review,,卷期:2010年16-34]
- The role of hepatitis C virus (HCV) infection in the development of vascular disease is controversial. Insulin resistance (IR) is a recognized risk factor for cardiovascular disease (CVD) and is associated with chronic h...
- Preventing Type 2 Diabetes Mellitus: Room for Residual Risk Reduction After Lifestyle Changes?
[作者:Athyros, VG; Tziomalos, K; Karagiannis, A; Mikhailidis, DP,期刊:Current Pharmaceutical Design, 页码:3839-3847 , 文章类型: Review,,卷期:2010年16-34]
- It is well known that type 2 diabetes mellitus (T2DM) is a major risk factor for cardiovascular diseases (CVD). A predicted worldwide increase in the incidence of T2DM, taking the form of an epidemic, is expected to indu...
- Sodium-Glucose Co-Transporter 2 Inhibitors: From Apple Tree to 'Sweet Pee'
[作者:Hardman, TC; Rutherford, P; Dubrey, SW; Wierzbicki, AS,期刊:Current Pharmaceutical Design, 页码:3830-3838 , 文章类型: Review,,卷期:2010年16-34]
- The sodium-glucose co-transporter 2 (SGLT2), located in the plasma membrane of cells lining the proximal tubule, facilitates the reabsorption of glucose in the kidney. Inhibition of SGLT2 has the potential to reduce bloo...
- The Antiplatelet and Antithrombotic Actions of Statins
[作者:Mitsios, JV; Papathanasiou, AI; Goudevenos, JA; Tselepis, AD,期刊:Current Pharmaceutical Design, 页码:3808-3814 , 文章类型: Review,,卷期:2010年16-34]
- Several studies over the last years have demonstrated that statins exhibit actions beyond that of lipid-lowering (pleiotropic effects) ranging from improving endothelial function, modulating the inflammatory response, ma...
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