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  • The Conformation and Function of a Multimodular Glycogen-Degrading Pneumococcal Virulence Factor
    [作者:van Bueren, AL; Ficko-Blean, E; Pluvinage, B; Hehemann, JH; Higgins, MA; Deng, LH; Ogunniyi, AD; Stroeher, UH; El Warry, N; Burke, RD; Czjzek, M; Paton, JC; Vocadlo, DJ; Boraston, AB,期刊:Structure, 页码:640-651 , 文章类型: Article,,卷期:2011年19-5]
  • SpuA is a large multimodular cell wall-attached enzyme involved in the degradation of glycogen by the pathogenic bacterium Streptococcus pneumoniae. The deletion of the gene encoding SpuA from the bacterium resulted in a...
  • Advanced Glycation End Product Recognition by the Receptor for AGEs
    [作者:Xue, J; Rai, V; Singer, D; Chabierski, S; Xie, JJ; Reverdatto, S; Burz, DS; Schmidt, AM; Hoffmann, R; Shekhtman, A,期刊:Structure, 页码:722-732 , 文章类型: Article,,卷期:2011年19-5]
  • Nonenzymatic protein glycation results in the formation of advanced glycation end products (AGEs) that are implicated in the pathology of diabetes, chronic inflammation, Alzheimer's disease, and cancer. AGEs mediate thei...