- Epicardial-Derived Cell Epithelial-to-Mesenchymal Transition and Fate Specification Require PDGF Receptor Signaling
[作者：Smith, CL; Baek, ST; Sung, CY; Tallquist, MD,期刊：Circulation Research, 页码：E15-U28 , 文章类型： Article，,卷期：2011年108-12]
- Rationale: In early heart development, platelet-derived growth factor (PDGF) receptor expression in the heart ventricles is restricted to the epicardium. Previously, we showed that PDGFR beta is required for coronary vas...
- Antiangiogenic Activity of rPAI-1(23) Promotes Vasa Vasorum Regression in Hypercholesterolemic Mice Through a Plasmin-Dependent Mechanism
[作者：Mollmark, J; Ravi, S; Sun, BM; Shipman, S; Buitendijk, M; Simons, M; Mulligan-Kehoe, MJ,期刊：Circulation Research, 页码：1419-U54 , 文章类型： Article，,卷期：2011年108-12]
- Rationale: The antiangiogenic activity of rPAI-1(23), a truncated plasminogen activator inhibitor-1 (PAI-1) protein, induces vasa vasorum collapse and significantly reduces plaque area and plaque cholesterol in hyperchol...
- Small Heat Shock Protein 20 Interacts With Protein Phosphatase-1 and Enhances Sarcoplasmic Reticulum Calcium Cycling
[作者：Qian, J; Vafiadaki, E; Florea, SM; Singh, VP; Song, WZ; Lam, CK; Wang, YG; Yuan, QY; Pritchard, TJ; Cai, WF; Haghighi, K; Rodriguez, P; Wang, HS; Sanoudou, D; Fan, GC; Kranias, EG,期刊：Circulation Research, 页码：1429-U75 , 文章类型： Article，,卷期：2011年108-12]
- Background: Heat shock proteins (Hsp) are known to enhance cell survival under various stress conditions. In the heart, the small Hsp20 has emerged as a key mediator of protection against apoptosis, remodeling, and ische...
- Intermittent Hypoxia in Rats Increases Myogenic Tone Through Loss of Hydrogen Sulfide Activation of Large-Conductance Ca2+-Activated Potassium Channels
[作者：Jackson-Weaver, O; Paredes, DA; Bosc, LVG; Walker, BR; Kanagy, NL,期刊：Circulation Research, 页码：1439-U101 , 文章类型： Article，,卷期：2011年108-12]
- Rationale: Myogenic tone, an important regulator of vascular resistance, is dependent on vascular smooth muscle (VSM) depolarization, can be modulated by endothelial factors, and is increased in several models of hyperte...
- Exercise Protects Against Myocardial Ischemia-Reperfusion Injury via Stimulation of beta(3)-Adrenergic Receptors and Increased Nitric Oxide Signaling: Role of Nitrite and Nitrosothiols
[作者：Calvert, JW; Condit, ME; Aragon, JP; Nicholson, CK; Moody, BF; Hood, RL; Sindler, AL; Gundewar, S; Seals, DR; Barouch, LA; Lefer, DJ,期刊：Circulation Research, 页码：1448-U125 , 文章类型： Article，,卷期：2011年108-12]
- Rationale: Exercise training confers sustainable protection against ischemia-reperfusion injury in animal models and has been associated with improved survival following a heart attack in humans. It is still unclear how ...
- Phosphatase-Resistant Gap Junctions Inhibit Pathological Remodeling and Prevent Arrhythmias
[作者：Remo, BF; Qu, JX; Volpicelli, FM; Giovannone, S; Shin, D; Lader, J; Liu, FY; Zhang, J; Lent, DS; Morley, GE; Fishman, GI,期刊：Circulation Research, 页码：1459-U138 , 文章类型： Article，,卷期：2011年108-12]
- Rationale: Posttranslational phosphorylation of connexin43 (Cx43) has been proposed as a key regulatory event in normal cardiac gap junction expression and pathological gap junction remodeling. Nonetheless, the role of C...
- Insulin-Like Growth Factor-1 Receptor Identifies a Pool of Human Cardiac Stem Cells With Superior Therapeutic Potential for Myocardial Regeneration
[作者：D'Amario, D; Cabral-Da-Silva, MC; Zheng, HQ; Fiorini, C; Goichberg, P; Steadman, E; Ferreira-Martins, J; Sanada, F; Piccoli, M; Cappetta, D; D'Alessandro, DA; Michler, RE; Hosoda, T; Anastasia, L; Rota, M; Leri, A; Anversa, P; Kajstura, J,期刊：Circulation Research, 页码：1467-U178 , 文章类型： Article，,卷期：2011年108-12]
- Rationale: Age and coronary artery disease may negatively affect the function of human cardiac stem cells (hCSCs) and their potential therapeutic efficacy for autologous cell transplantation in the failing heart. Objecti...
- Cell-Matrix Interactions in the Pathobiology of Calcific Aortic Valve Disease Critical Roles for Matricellular, Matricrine, and Matrix Mechanics Cues
[作者：Chen, JH; Simmons, CA,期刊：Circulation Research, 页码：1510-1524 , 文章类型： Review，,卷期：2011年108-12]
- The hallmarks of calcific aortic valve disease (CAVD) are the significant changes that occur in the organization, composition, and mechanical properties of the extracellular matrix (ECM), ultimately resulting in stiffene...
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