- Combination of vorinostat and adenovirus-TRAIL exhibits a synergistic antitumor effect by increasing transduction and transcription of TRAIL in lung cancer cells
[作者:Kim, DR; Park, MY; Lee, CS; Shim, SH; Yoon, HI; Lee, JH; Sung, MW; Kim, YS; Lee, CT,期刊:Cancer gene therapy, 页码:467-477 , 文章类型: Article,,卷期:2011年18-7]
- Soluble TRAIL and adenovirus (ad)-TRAIL exhibit a strong antitumor effect by inducing apoptosis. Vorinostat is the histone deacetylase (HDAC) inhibitor that induces cell death in cancer cell lines and regulates the expre...
- The roles of cell surface attachment molecules and coagulation Factor X in adenovirus 5-mediated gene transfer in pancreatic cancer cells
[作者:Hamdan, S; Verbeke, CS; Fox, N; Booth, J; Bottley, G; Pandha, HS; Blair, GE,期刊:Cancer gene therapy, 页码:478-488 , 文章类型: Article,,卷期:2011年18-7]
- Transduction of 11 pancreatic cancer cell lines with a replication-deficient adenovirus 5 expressing enhanced green fluorescent protein (Ad5EGFP) was analyzed and variable EGFP levels were observed, ranging from <1% to s...
- Adjuvant effect of HER-2/neu-specific adenoviral vector stimulating CD8(+) T and natural killer cell responses on anti-HER-2/neu antibody therapy for well-established breast tumors in HER-2/neu transgenic mice
[作者:Chen, Y; Xie, Y; Chan, T; Sami, A; Ahmed, S; Liu, Q; Xiang, J,期刊:Cancer gene therapy, 页码:489-499 , 文章类型: Article,,卷期:2011年18-7]
- Approximately one third of patients with advanced human epidermal growth factor receptor 2 (HER-2)/neu-positive breast cancer respond to trastuzumab monotherapy, a humanized anti-HER-2/neu antibody. However, de novo and ...
- Identification of microRNA-target interaction in APRIL-knockdown colorectal cancer cells
[作者:Wang, F; Ding, W; Wang, J; Jing, R; Wang, X; Cong, H; Wang, Y; Ju, S; Wang, H,期刊:Cancer gene therapy, 页码:500-509 , 文章类型: Article,,卷期:2011年18-7]
- MicroRNAs (miRNAs) regulate mammalian gene expression by targeting mRNAs and have key roles in several cellular processes, including differentiation, development, apoptosis and cancer pathomechanisms. Our previous studie...
- MDA-7 results in downregulation of AKT concomitant with apoptosis and cell cycle arrest in breast cancer cells
[作者:Valero, V; Wingate, H; Chada, S; Liu, Y; Palalon, F; Mills, G; Keyomarsi, K; Hunt, KK,期刊:Cancer gene therapy, 页码:510-519 , 文章类型: Article,,卷期:2011年18-7]
- The melanoma differentiation-associated gene-7 (mda-7) is a known mediator of apoptosis in cancer cells but not in normal cells. We hypothesized that MDA-7 interferes with the prosurvival signaling pathways that are comm...
- DNA triplex-mediated inhibition of MET leads to cell death and tumor regression in hepatoma
[作者:Singhal, G; Akhter, MZ; Stern, DF; Gupta, SD; Ahuja, A; Sharma, U; Jagannathan, NR; Rajeswari, MR,期刊:Cancer gene therapy, 页码:520-530 , 文章类型: Article,,卷期:2011年18-7]
- Mesenchymal epithelial transition factor (MET) is one of the critical cell signaling molecules whose aberrant expression is reported in several human cancers. The aim of the study is to investigate the antigene and antip...
- Engineering a waste management enzyme to overcome cancer resistance to apoptosis: adding DNase1 to the anti-cancer toolbox (vol 18, pg 346, 2011)
[作者:Rosner, K; Kasprzak, MF; Horenstein, ACJ; Thurston, HL; Abrams, J; Kerwin, LY; Mehregan, DA; Mehregan, DR,期刊:Cancer gene therapy, 页码:531-531 , 文章类型: Correction,,卷期:2011年18-7]
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