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文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共15条记录   Primed for Pluripotency [作者：Kunath, T,期刊：Cell Stem Cell, 页码：241-242 , 文章类型： Editorial Material，,卷期：2011年8-3] To date, pluripotent epiblast stem cells (EpiSCs) had only been derived from postimplantation mouse embryos. In this issue of Cell Stem Cell, Najm et al. (2011) demonstrate that EpiSCs can be routinely derived from preim... Clever Leukemic Stem Cells Branch Out [作者：Vyas, P; Jacobsen, SEW,期刊：Cell Stem Cell, 页码：242-244 , 文章类型： Editorial Material，,卷期：2011年8-3] Individual tumors harbor heterogeneous populations of genetically distinct subclones. Two recent papers in Nature by Notta et al. (2011) and Anderson et al. (2011) reveal genetic heterogeneity in functional leukemic stem... Stem Cells and beta Cells: The Same, but Different? [作者：Murtaugh, LC,期刊：Cell Stem Cell, 页码：244-245 , 文章类型： Editorial Material，,卷期：2011年8-3] Researchers have long debated whether new pancreatic beta cells derive from stem cells or from pre-existing beta cells. A new study in this issue of Cell Stem Cell (Smukler et al., 2011) suggests that both sides may be r... Safely Modulating the Immune System in Regenerative Medicine [作者：Pera, MF,期刊：Cell Stem Cell, 页码：246-247 , 文章类型： Editorial Material，,卷期：2011年8-3] The destruction of pluripotent stem cell-derived grafts by the host immune system presents a significant barrier to clinical translation of cell therapies. Pearl et al. (2011) report in this issue of Cell Stem Cell that ... Kidney Stem Cells Found in Adult Zebrafish [作者：Zeng, XK; Hou, SX,期刊：Cell Stem Cell, 页码：247-249 , 文章类型： Editorial Material，,卷期：2011年8-3] Recently in Nature, Davidson and coworkers (Diep et al., 2011) identified nephron progenitors/stem cells located at the point of fusion with the pronephric tubules in adult zebrafish. Clumps of progenitors give rise to f... Ernest McCulloch Obituary [作者：Iscove, N,期刊：Cell Stem Cell, 页码：250-251 , 文章类型： Biographical-Item，,卷期：2011年8-3] Biomimetic Platforms for Human Stem Cell Research [作者：Vunjak-Novakovic, G; Scadden, DT,期刊：Cell Stem Cell, 页码：252-261 , 文章类型： Article，,卷期：2011年8-3] Stem cells are central to developing new treatment options for tissue regeneration and constructing controllable models for biological research. Bioengineered cell culture environments that combine microenvironmental con... Phosphoryl-EZH-ion [作者：Caretti, G; Palacios, D; Sartorelli, V; Puri, PL,期刊：Cell Stem Cell, 页码：262-265 , 文章类型： Review，,卷期：2011年8-3] Polycomb group (PcG) proteins regulate gene expression in embryonic and adult stem cells, but the mechanisms responsible for PcG gene targeting and regulation remain largely unknown. Recent evidence shows that EZH2, the ... LRRK2 Mutant iPSC-Derived DA Neurons Demonstrate Increased Susceptibility to Oxidative Stress [作者：Ha, NN; Byers, B; Cord, B; Shcheglovitov, A; Byrne, J; Gujar, P; Kee, K; Schule, B; Dolmetsch, RE; Langston, W; Palmer, TD; Pera, RR,期刊：Cell Stem Cell, 页码：267-280 , 文章类型： Article，,卷期：2011年8-3] Studies of Parkinson's disease (PD) have been hindered by lack of access to affected human dopaminergic (DA) neurons. Here, we report generation of induced pluripotent stem cells that carry the p.G2019S mutation (G2019S-... The Adult Mouse and Human Pancreas Contain Rare Multipotent Stem Cells that Express Insulin [作者：Smukler, SR; Arntfield, ME; Razavi, R; Bikopoulos, G; Karpowicz, P; Seaberg, R; Dai, FH; Lee, S; Ahrens, R; Fraser, PE; Wheeler, MB; van der Kooy, D,期刊：Cell Stem Cell, 页码：281-293 , 文章类型： Article，,卷期：2011年8-3] The search for putative precursor cells within the pancreas has been the focus of extensive research. Previously, we identified rare pancreas-derived multipotent precursor (PMP) cells in the mouse with the intriguing cap... Specific MicroRNAs Are Preferentially Expressed by Skin Stem Cells To Balance Self-Renewal and Early Lineage Commitment [作者：Zhang, LA; Stokes, N; Polak, L; Fuchs, E,期刊：Cell Stem Cell, 页码：294-308 , 文章类型： Article，,卷期：2011年8-3] Increasing evidence suggests that microRNAs may play important roles in regulating self-renewal and differentiation in mammalian stem cells (SCs). Here, we explore this issue in skin. We first characterize microRNA expre... Short-Term Immunosuppression Promotes Engraftment of Embryonic and Induced Pluripotent Stem Cells [作者：Pearl, JI; Lee, AS; Leveson-Gower, DB; Sun, N; Ghosh, Z; Lan, F; Ransohoff, J; Negrin, RS; Davis, MM; Wu, JC,期刊：Cell Stem Cell, 页码：309-317 , 文章类型： Article，,卷期：2011年8-3] Embryonic stem cells (ESCs) are an attractive source for tissue regeneration and repair therapies because they can be differentiated into virtually any cell type in the adult body. However, for this approach to succeed, ... Isolation of Epiblast Stem Cells from Preimplantation Mouse Embryos [作者：Najm, FJ; Chenoweth, JG; Anderson, PD; Nadeau, JH; Redline, RW; McKay, RDG; Tesar, PJ,期刊：Cell Stem Cell, 页码：318-325 , 文章类型： Article，,卷期：2011年8-3] Pluripotent stem cells provide a platform to interrogate control elements that function to generate all cell types of the body. Despite their utility for modeling development and disease, the relationship of mouse and hu... FGF2 Sustains NANOG and Switches the Outcome of BMP4-Induced Human Embryonic Stem Cell Differentiation [作者：Yu, PZ; Pan, GJ; Yu, JY; Thomson, JA,期刊：Cell Stem Cell, 页码：326-334 , 文章类型： Article，,卷期：2011年8-3] Here, we show that as human embryonic stem cells (ESCs) exit the pluripotent state, NANOG can play a key role in determining lineage outcome. It has previously been reported that BMPs induce differentiation of human ESCs... Targeting SOX17 in Human Embryonic Stem Cells Creates Unique Strategies for Isolating and Analyzing Developing Endoderm [作者：Wang, P; Rodriguez, RT; Wang, J; Ghodasara, A; Kim, SK,期刊：Cell Stem Cell, 页码：335-346 , 文章类型： Article，,卷期：2011年8-3] Human embryonic stem cells (hESCs) can provide insights into development of inaccessible human tissues such as embryonic endoderm. Progress in this area has been hindered by a lack of methods for isolating endodermal cel...