- A Repair "Kit" for the Infarcted Heart
[作者:Mignone, JL; Murry, CE,期刊:Cell Stem Cell, 页码:350-352 , 文章类型: Editorial Material,,卷期:2011年8-4]
- Transplanted, c-kit expressing marrow-derived progenitors can enhance the function of an infarcted heart, but the mechanism remains unclear. In this issue of Cell Stem Cell, Loffredo et al. (2011) provide evidence that h...
- Food For Thought: Neural Stem Cells on a Diet
[作者:Ables, ET; Drummond-Barbosa, D,期刊:Cell Stem Cell, 页码:352-354 , 文章类型: Editorial Material,,卷期:2011年8-4]
- Growing evidence shows that stem cells are modulated by systemic factors that are integrated with local signals in response to physiological status. Two recent Cell (Chell and Brand, 2010) and Nature (Sousa-Nunes et al.,...
- A Call for Standardized Naming and Reporting of Human ESC and iPSC Lines
[作者:Luong, MX; Auerbach, J; Crook, JM; Daheron, L; Hei, D; Lomax, G; Loring, JF; Ludwig, T; Schlaeger, TM; Smith, KP; Stacey, G; Xu, RH; Zeng, FY,期刊:Cell Stem Cell, 页码:357-359 , 文章类型: Editorial Material,,卷期:2011年8-4]
- Human embryonic and induced pluripotent stem cell lines are being generated at a rapid pace and now number in the thousands. We propose a standard nomenclature and suggest the use of a centralized database for all cell l...
- Defects in Trophoblast Cell Lineage Account for the Impaired In Vivo Development of Cloned Embryos Generated by Somatic Nuclear Transfer
[作者:Lin, JW; Shi, LY; Zhang, M; Yang, H; Qin, YR; Zhang, J; Gong, DQ; Zhang, X; Li, DS; Li, JS,期刊:Cell Stem Cell, 页码:371-375 , 文章类型: Article,,卷期:2011年8-4]
- The low success rate of somatic nuclear transfer (NT) is hypothesized to be mainly due to functional defects in the trophoblast cell lineage rather than the inner cell mass (ICM); this hypothesis, however, remains to be ...
- Highly Efficient miRNA-Mediated Reprogramming of Mouse and Human Somatic Cells to Pluripotency
[作者:Anokye-Danso, F; Trivedi, CM; Juhr, D; Gupta, M; Cui, Z; Tian, Y; Zhang, YZ; Yang, WL; Gruber, PJ; Epstein, JA; Morrisey, EE,期刊:Cell Stem Cell, 页码:376-388 , 文章类型: Article,,卷期:2011年8-4]
- Transcription factor-based cellular reprogramming has opened the way to converting somatic cells to a pluripotent state, but has faced limitations resulting from the requirement for transcription factors and the relative...
- Bone Marrow-Derived Cell Therapy Stimulates Endogenous Cardiomyocyte Progenitors and Promotes Cardiac Repair
[作者:Loffredo, FS; Steinhauser, ML; Gannon, J; Lee, RT,期刊:Cell Stem Cell, 页码:389-398 , 文章类型: Article,,卷期:2011年8-4]
- Cell therapy can improve cardiac function in animals and humans after injury, but the mechanism is unclear,. We performed cell therapy experiments in genetically engineered mice that permanently express green fluorescent...
- Targeting HIF1 alpha Eliminates Cancer Stem Cells in Hematological Malignancies
[作者:Wang, Y; Liu, Y; Malek, SN; Zheng, P; Liu, Y,期刊:Cell Stem Cell, 页码:399-411 , 文章类型: Article,,卷期:2011年8-4]
- Molecular targeting of cancer stem cells (CSCs) has therapeutic potential for efficient treatment of cancer, although relatively few specific targets have been identified so far. Hypoxia-inducible factor (HIF) was recent...
- Adult Hematopoiesis is Regulated by TIF1 gamma, a Repressor of TAL1 and PU.1 Transcriptional Activity
[作者:Kusy, S; Gault, N; Ferri, F; Lewandowski, D; Barroca, V; Jaracz-Ros, A; Losson, R; Romeo, PH,期刊:Cell Stem Cell, 页码:412-425 , 文章类型: Article,,卷期:2011年8-4]
- Crosstalk between transcription factors and cytokines precisely regulates tissue homeostasis. Transcriptional intermediary factor 1 gamma (TIF1 gamma) regulates vertebrate hematopoietic development, can control transcrip...
- Mutant Human Embryonic Stem Cells Reveal Neurite and Synapse Formation Defects in Type 1 Myotonic Dystrophy
[作者:Marteyn, A; Maury, Y; Gauthier, MM; Lecuyer, C; Vernet, R; Denis, JA; Pietu, G; Peschanski, M; Martinat, C,期刊:Cell Stem Cell, 页码:434-444 , 文章类型: Article,,卷期:2011年8-4]
- Myotonic dystrophy type 1 (DM1) is a multisystem disorder affecting a variety of organs, including the central nervous system. By using neuronal progeny derived from human embryonic stem cells carrying the causal DM1 mut...
- Prostaglandin E2 Enhances Human Cord Blood Stem Cell Xenotransplants and Shows Long-Term Safety in Preclinical Nonhuman Primate Transplant Models
[作者:Goessling, W; Allen, RS; Guan, X; Jin, P; Uchida, N; Dovey, M; Harris, JM; Metzger, ME; Bonifacino, AC; Stroncek, D; Stegner, J; Armant, M; Schlaeger, T; Tisdale, JF; Zon, LI; Donahue, RE; North, TE,期刊:Cell Stem Cell, 页码:445-458 , 文章类型: Article,,卷期:2011年8-4]
- Hematopoietic stem cells (HSCs) are used in transplantation therapy to reconstitute the hematopoietic system. Human cord blood (hCB) transplantation has emerged as an attractive alternative treatment option when traditio...
- iPSCs: Induced Back to Controversy
[作者:Panopoulos, AD; Ruiz, S; Belmonte, JCI,期刊:Cell Stem Cell, 页码:347-348 , 文章类型: Editorial Material,,卷期:2011年8-4]
- Several recent reports (Mayshar et al., 2010; Laurent et al., 2011; Lister et al., 2011; Gore et al., 2011; Hussein et al., 21)11) uncover genetic and epigenetic alterations in induced pluripotent stem cells, stimulating...
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