- Reprogramming of Trophoblast Stem Cells into Pluripotent Stem Cells by Oct4
[作者:Wu, T; Wang, H; He, J; Kang, L; Jiang, YH; Liu, JC; Zhang, Y; Kou, ZH; Liu, LJ; Zhang, XH; Gao, SR,期刊:Stem Cells, 页码:755-763 , 文章类型: Article,,卷期:2011年29-5]
- ESCs and trophoblast stem (TS) cells are both derived from early embryos, yet these cells have distinct differentiation properties. ESCs can differentiate into all three germ layer cell types, whereas TS cells can only d...
- Snail and the microRNA-200 Family Act in Opposition to Regulate Epithelial-to-Mesenchymal Transition and Germ Layer Fate Restriction in Differentiating ESCs
[作者:Gill, JG; Langer, EM; Lindsley, RC; Cai, M; Murphy, TL; Kyba, M; Murphy, KM,期刊:Stem Cells, 页码:764-776 , 文章类型: Article,,卷期:2011年29-5]
- The reprogramming of somatic cells to inducible pluripotent stem cells requires a mesenchymal-to-epithelial transition. While differentiating ESCs can undergo the reverse process or epithelial-to-mesenchymal transition (...
- Assessment of the Myogenic Stem Cell Compartment Following Transplantation of Pax3/Pax7-Induced Embryonic Stem Cell-Derived Progenitors
[作者:Darabi, R; Santos, FNC; Filareto, A; Pan, WH; Koene, R; Rudnicki, MA; Kyba, M; Perlingeiro, RCR,期刊:Stem Cells, 页码:777-790 , 文章类型: Article,,卷期:2011年29-5]
- An effective long-term cell therapy for skeletal muscle regeneration requires donor contribution to both muscle fibers and the muscle stem cell pool. Although satellite cells have these abilities, their therapeutic poten...
- RCOR2 Is a Subunit of the LSD1 Complex That Regulates ESC Property and Substitutes for SOX2 in Reprogramming Somatic Cells to Pluripotency
[作者:Yang, P; Wang, YX; Chen, JY; Li, H; Kang, L; Zhang, Y; Chen, S; Zhu, B; Gao, SR,期刊:Stem Cells, 页码:791-801 , 文章类型: Article,,卷期:2011年29-5]
- Histone demethylase LSD1 can form complex with different Rcor family corepressors in different cell types. It remains unknown if cell-specific Rcor proteins function specifically in distinct cell types. Here, we report t...
- The Controlled Generation of Functional Basal Forebrain Cholinergic Neurons from Human Embryonic Stem Cells
[作者:Bissonnette, CJ; Lyass, L; Bhattacharyya, BJ; Belmadani, A; Miller, RJ; Kessler, JA,期刊:Stem Cells, 页码:802-811 , 文章类型: Article,,卷期:2011年29-5]
- An early substantial loss of basal forebrain cholinergic neurons (BFCN) is a constant feature of Alzheimer's disease and is associated with deficits in spatial learning and memory. The ability to selectively control the ...
- Human Mesenchymal Stem Cells Reprogram Adult Cardiomyocytes Toward a Progenitor-Like State Through Partial Cell Fusion and Mitochondria Transfer
[作者:Acquistapace, A; Bru, T; Lesault, PF; Figeac, F; Coudert, AE; le Coz, O; Christov, C; Baudin, X; Auber, F; Yiou, R; Dubois-Rande, JL; Rodriguez, AM,期刊:Stem Cells, 页码:812-824 , 文章类型: Article,,卷期:2011年29-5]
- Because stem cells are often found to improve repair tissue including heart without evidence of engraftment or differentiation, mechanisms underlying wound healing are still elusive. Several studies have reported that st...
- Human Induced Pluripotent Stem-Derived Retinal Pigment Epithelium (RPE) Cells Exhibit Ion Transport, Membrane Potential, Polarized Vascular Endothelial Growth Factor Secretion, and Gene Expression Pattern Similar to Native RPE
[作者:Kokkinaki, M; Sahibzada, N; Golestaneh, N,期刊:Stem Cells, 页码:825-835 , 文章类型: Article,,卷期:2011年29-5]
- Age-related macular degeneration (AMD) is one of the major causes of blindness in aging population that progresses with death of retinal pigment epithelium (RPE) and photoreceptor degeneration inducing impairment of cent...
- Wnt Signaling Promotes Neuronal Differentiation from Mesenchymal Stem Cells Through Activation of Tlx3
[作者:Kondo, T; Matsuoka, AJ; Shimomura, A; Koehler, KR; Chan, RJ; Miller, JM; Srour, EF; Hashino, E,期刊:Stem Cells, 页码:836-846 , 文章类型: Article,,卷期:2011年29-5]
- Wnt/beta-catenin signaling promotes neural differentiation by activation of the neuron-specific transcription factors, Neurogenin1 (Ngn1), NeuroD, and Brn3a, in the nervous system. As neurons in cranial sensory ganglia a...
- Combined Characterization of microRNa and mRNa Profiles Delineates Early Differentiation Pathways of CD133(+) and CD34(+) Hematopoietic Stem and Progenitor Cells
[作者:Bissels, U; Wild, S; Tomiuk, S; Hafner, M; Scheel, H; Mihailovic, A; Choi, YH; Tuschl, T; Bosio, A,期刊:Stem Cells, 页码:847-857 , 文章类型: Article,,卷期:2011年29-5]
- MicroRNAs (miRNAs) have been shown to play an important role in hematopoiesis. To elucidate the role of miRNAs in the early steps of hematopoiesis, we directly compared donor-matched CD133(+) cells with the more differen...
- Differentiation Potential of Human Postnatal Mesenchymal Stem Cells, Mesoangioblasts, and Multipotent Adult Progenitor Cells Reflected in Their Transcriptome and Partially Influenced by the Culture Conditions
[作者:Roobrouck, VD; Clavel, C; Jacobs, SA; Ulloa-Montoya, F; Crippa, S; Sohni, A; Roberts, SJ; Luyten, FP; Van Gool, SW; Sampaolesi, M; Delforge, M; Luttun, A; Verfaillie, CM,期刊:Stem Cells, 页码:871-882 , 文章类型: Article,,卷期:2011年29-5]
- Several adherent postnatal stem cells have been described with different phenotypic and functional properties. As many of these cells are being considered for clinical therapies, it is of great importance that the identi...
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