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文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共16条记录   Double Take on Piwi Protein/piRNA Complex Structure [作者：Schwalbe, H,期刊：Structure, 页码：141-142 , 文章类型： Editorial Material，,卷期：2011年19-2] Recognition of Archaeal CRISPR RNA: No P in the alindromic Repeat? [作者：Lawrence, CM; White, MF,期刊：Structure, 页码：142-144 , 文章类型： Editorial Material，,卷期：2011年19-2] Protein Kinase C Regulation: C1 Meets C-tail [作者：Kazanietz, MG; Lemmon, MA,期刊：Structure, 页码：144-146 , 文章类型： Editorial Material，,卷期：2011年19-2] A Ferritin-Based Label for Cellular Electron Cryotomography [作者：Wang, Q; Mercogliano, CP; Lowe, J,期刊：Structure, 页码：147-154 , 文章类型： Article，,卷期：2011年19-2] Electron cryotomography provides nanometer resolution structural detail of thin biological specimens in a near-native state. Currently, its application is limited by the lack of a specific label for the identification of... Cross-Crystal Averaging with Search Models to Improve Molecular Replacement Phases [作者：Li, WK; Li, F,期刊：Structure, 页码：155-161 , 文章类型： Article，,卷期：2011年19-2] The application of molecular replacement (MR) in macromolecular crystallography can be limited by the "model bias" problem. Here we propose a strategy to reduce model bias when only part of a new structure is known: afte... Decoy Strategies: The Structure of TL1A:DcR3 Complex [作者：Zhan, CY; Patskovsky, Y; Yan, QR; Li, ZH; Ramagopal, U; Cheng, HY; Brenowitz, M; Hui, XA; Nathenson, SG; Almo, SC,期刊：Structure, 页码：162-171 , 文章类型： Article，,卷期：2011年19-2] Decoy Receptor 3 (DcR3), a secreted member of the Tumor Necrosis Factor (TNF) receptor superfamily, neutralizes three different TNF ligands: FasL, LIGHT, and TL1A. Each of these ligands engages unique signaling receptors... Recognition of 2 '-O-Methylated 3 '-End of piRNA by the PAZ Domain of a Piwi Protein [作者：Simon, B; Kirkpatrick, JP; Eckhardt, S; Reuter, M; Rocha, EA; Andrade-Navarro, MA; Sehr, P; Pillai, RS; Carlomagno, T,期刊：Structure, 页码：172-180 , 文章类型： Article，,卷期：2011年19-2] Piwi proteins are germline-specific Argonautes that associate with small RNAs called Piwi-interacting RNAs (piRNAs), and together with these RNAs are implicated in transposon silencing. The PAZ domain of Argonaute protei... Structural Insights into the Oligomerization and Architecture of Eukaryotic Membrane Pore-Forming Toxins [作者：Mechaly, AE; Bellomio, A; Gil-Carton, D; Morante, K; Valle, M; Gonzalez-Manas, JM; Guerin, DMA,期刊：Structure, 页码：181-191 , 文章类型： Article，,卷期：2011年19-2] Pore-forming toxins (PFTs) are proteins that are secreted as soluble molecules and are inserted into membranes to form oligomeric transmembrane pores. In this paper, we report the crystal structure of Fragaceatoxin C (Fr... Structural Basis of Streptococcus pyogenes Immunity to Its NAD(+) Glycohydrolase Toxin [作者：Smith, CL; Ghosh, J; Elam, JS; Pinkner, JS; Hultgren, SJ; Caparon, MG; Ellenberger, T,期刊：Structure, 页码：192-202 , 文章类型： Article，,卷期：2011年19-2] The virulence of Gram-positive bacteria is enhanced by toxins like the Streptococcus pyogenes (beta-NAD(+) glycohydrolase known as SPN. SPN-producing strains of S. pyogenes additionally express the protein immunity facto... Structural Model and trans-Interaction of the Entire Ectodomain of the Olfactory Cell Adhesion Molecule [作者：Kulahin, N; Kristensen, O; Rasmussen, KK; Olsen, L; Rydberg, P; Vestergaard, B; Kastrup, JS; Berezin, V; Bock, E; Walmod, PS; Gajhede, M,期刊：Structure, 页码：203-211 , 文章类型： Article，,卷期：2011年19-2] The ectodomain of olfactory cell adhesion molecule (OCAM/NCAM2/RNCAM) consists of five immunoglobulin (Ig) domains (IgI-V), followed by two fibronectin-type 3 (Fn3) domains (Fn3I-II). A complete structural model of the e... Molecular Mimicry and Ligand Recognition in Binding and Catalysis by the Histone Demethylase LSD1-CoREST Complex [作者：Baron, R; Binda, C; Tortorici, M; McCammon, JA; Mattevi, A,期刊：Structure, 页码：212-220 , 文章类型： Article，,卷期：2011年19-2] Histone demethylases LSD1 and LSD2 (KDM1A/B) catalyze the oxidative demethylation of Lys4 of histone H3. We used molecular dynamics simulations to probe the diffusion of the oxygen substrate. Oxygen can reach the catalyt... Structure of the Rtt109-AcCoA/Vps75 Complex and Implications for Chaperone-Mediated Histone Acetylation [作者：Tang, Y; Holbert, MA; Delgoshaie, N; Wurtele, H; Guillemette, B; Meeth, K; Yuan, H; Drogaris, P; Lee, EH; Durette, C; Thibault, P; Verreault, A; Cole, PA; Marmorstein, R,期刊：Structure, 页码：221-231 , 文章类型： Article，,卷期：2011年19-2] Yeast Rtt109 promotes nucleosome assembly and genome stability by acetylating K9, K27, and K56 of histone H3 through interaction with either of two distinct histone chaperones, Vps75 or Asf1. We report the crystal struct... Mechanism for the Alteration of the Substrate Specificities of Template-Independent RNA Polymerases [作者：Toh, Y; Takeshita, D; Nagaike, T; Numata, T; Tomita, K,期刊：Structure, 页码：232-243 , 文章类型： Article，,卷期：2011年19-2] PolyA polymerase (PAP) adds a polyA tail onto the 3'-end of RNAs without a nucleic acid template, using adenosine-5'-triphosphate (ATP) as a substrate. The mechanism for the substrate selection by eubacterial PAP remains... The Extracellular Architecture of Adherens Junctions Revealed by Crystal Structures of Type I Cadherins [作者：Harrison, OJ; Jin, XS; Hong, SJ; Bahna, F; Ahlsen, G; Brasch, J; Wu, YH; Vendome, J; Felsovalyi, K; Hampton, CM; Troyanovsky, RB; Ben-Shau, A; Frank, J; Troyanovsky, SM; Shapiro, L; Honig, B,期刊：Structure, 页码：244-256 , 文章类型： Article，,卷期：2011年19-2] Adherens junctions, which play a central role in intercellular adhesion, comprise clusters of type I classical cadherins that bind via extracellular domains extended from opposing cell surfaces. We show that a molecular ... Interaction of the Cas6 Riboendonuclease with CRISPR RNAs: Recognition and Cleavage [作者：Wang, RY; Preamplume, G; Terns, MP; Terns, RM; Li, H,期刊：Structure, 页码：257-264 , 文章类型： Article，,卷期：2011年19-2] The CRISPRs (Clustered Regularly Interspaced Short Palindromic Repeats) found in prokaryotic genomes confer small RNA-mediated protection against viruses and other invaders. CRISPR loci contain iterations of a short repe... Realizing the Allosteric Potential of the Tetrameric Protein Kinase A RI alpha Holoenzyme [作者：Boettcher, AJ; Wu, JA; Kim, C; Yang, J; Bruystens, J; Cheung, N; Pennypacker, JK; Blumenthal, DA; Kornev, AP; Taylor, SS,期刊：Structure, 页码：265-276 , 文章类型： Article，,卷期：2011年19-2] PKA holoenzymes containing two catalytic (C) subunits and a regulatory (R) subunit dimer are activated cooperatively by cAMP. While cooperativity involves the two tandem cAMP binding domains in each R-subunit, additional...