- Polyion complex micelle MRI contrast agents from poly(ethylene glycol)-b-poly(L-lysine) block copolymers having Gd-DOTA; preparations and their control of T-1-relaxivities and blood circulation characteristics
[作者:Shiraishi, K; Kawano, K; Maitani, Y; Yokoyama, M,期刊:Journal of controlled release, 页码:160-167 , 文章类型: Article,,卷期:2010年148-2]
- The current study synthesized macromolecular magnetic resonance imaging (MRI) contrast agents constituted of the poly(ethylene glycol)-b-poly(L-lysine) block copolymer (PEG-P(Lys)). A chelate group, 1,4.7,10-tetraazacycl...
- Peritoneal retention of liposomes: Effects of lipid composition, PEG coating and liposome charge
[作者:Dadashzadeh, S; Mirahmadi, N; Babaei, MH; Vali, AM,期刊:Journal of controlled release, 页码:177-186 , 文章类型: Article,,卷期:2010年148-2]
- In the treatment of peritoneal carcinomatosis, systemic chemotherapy is not quite effective due to the poor penetration of cytotoxic agents into the peritoneal cavity, whereas intraperitoneal administration of chemothera...
- Oligoarginine-linked polymers as a new class of penetration enhancers
[作者:Sakuma, S; Suita, M; Masaoka, Y; Kataoka, M; Nakajima, N; Shinkai, N; Yamauchi, H; Hiwatari, K; Tachikawa, H; Kimura, R; Yamashita, S,期刊:Journal of controlled release, 页码:187-196 , 文章类型: Article,,卷期:2010年148-2]
- Oligoarginines, which are known as cell-penetrating peptides, enhance the cellular uptake of poorly membrane-permeable bioactive molecules that are chemically conjugated to them. We designed a novel polymer: oligoarginin...
- Route of administration-dependent anti-inflammatory effect of liposomal alendronate
[作者:Haber, E; Afergan, E; Epstein, H; Gutman, D; Koroukhov, N; Ben-David, M; Schachter, M; Golomb, G,期刊:Journal of controlled release, 页码:226-233 , 文章类型: Article,,卷期:2010年148-2]
- Innate immunity and inflammation are of major importance in various pathological conditions. Intravenous (IV) and intraperitoneal (IP) liposomal alendronate (LA) treatments have been shown to deplete circulating monocyte...
- Development of novel self-assembled DS-PLGA hybrid nanoparticles for improving oral bioavailability of vincristine sulfate by P-gp inhibition
[作者:Ling, GX; Zhang, P; Zhang, WP; Sun, J; Meng, XX; Qin, YM; Deng, YH; He, ZG,期刊:Journal of controlled release, 页码:241-248 , 文章类型: Article,,卷期:2010年148-2]
- To improve the encapsulation efficiency and oral bioavailability of vincristine sulfate (VCR), novel self-assembled dextran sulphate-PLGA hybrid nanoparticles (DPNs) were successfully developed using self-assembly and na...
- Nano PGE(1) promoted the recovery from spinal cord injury-induced motor dysfunction through its accumulation and sustained release
[作者:Takenaga, M; Ishihara, T; Ohta, Y; Tokura, Y; Hamaguchi, A; Igarashi, R; Mizushima, T,期刊:Journal of controlled release, 页码:249-254 , 文章类型: Article,,卷期:2010年148-2]
- The effect of Nano PCE1 (nanoparticles containing prostaglandin E-1) on spinal cord injury (SCI) was investigated in rat model. Nano PGE(1) significantly and dose-dependently promoted the recovery from SCI-induced motor ...
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