- Synthesis and Biological Evaluation of Oleanolic Acid Derivatives As Inhibitors of Protein Tyrosine Phosphatase 1B
[作者:Qian, S; Li, HJ; Chen, Y; Zhang, WY; Yang, SY; Wu, Y,期刊:Journal of natural products, 页码:1743-1750 , 文章类型: Article,,卷期:2010年73-11]
- Protein tyrosine phosphatase 1B (PTP1B) is a negative regulator in the process of insulin signaling and a promising drug target for diabetes and obesity. Derivatives of oleanolic acid were synthesized and evaluated as PT...
- 7-Nor-ergosterolide, a Pentalactone-Containing Norsteroid and Related Steroids from the Marine-Derived Endophytic Aspergillus ochraceus EN-31
[作者:Cui, CM; Li, XM; Meng, L; Li, CS; Huang, CG; Wang, BG,期刊:Journal of natural products, 页码:1780-1784 , 文章类型: Article,,卷期:2010年73-11]
- 7-Nor-ergosterolide (1), a rare 7-norsteroid with an unusual pentalactone B-ring system, and two new steroid derivatives, 3 beta,11 alpha-dihydroxyergosta-8,24(28)-dien-7-one (2) and 3 beta-hydroxyergosta-8,24(28)-dien-7...
- Hirsutalins A-H, Eunicellin-Based Diterpenoids from the Soft Coral Cladiella hirsuta
[作者:Chen, BW; Chang, SM; Huang, CY; Chao, CH; Su, JH; Wen, ZH; Hsu, CH; Dai, CF; Wu, YC; Sheu, JH,期刊:Journal of natural products, 页码:1785-1791 , 文章类型: Article,,卷期:2010年73-11]
- Eight new eunicellin-base diterpenoids, hirsutalins A-H (1-8), were isolated from the soft coral Cladiella hirsuta. Their structures were elucidated by spectroscopic methods, particularly in 1D and 2D NMR experiments. Th...
- Four Diphenylpropanes and a Cycloheptadibenzofuran from Bussea sakalava from the Madagascar Dry Forest
[作者:Pan, ED; Harinantenaina, L; Brodie, PJ; Miller, JS; Callmander, MW; Rakotonandrasana, S; Rakotobe, E; Rasamison, VE; Kingston, DGI,期刊:Journal of natural products, 页码:1792-1795 , 文章类型: Article,,卷期:2010年73-11]
- Investigation of the endemic Malagasy plant Bussea sakalava for antiproliferative activity against the A2780 ovarian cancer cell line led to the isolation of the four new diphenylpropanes 1-4 and the new cycloheptadibenz...
- Synthesis of Antimitotic Polyalkoxyphenyl Derivatives of Combretastatin Using Plant Allylpolyalkoxybenzenes
[作者:Semenov, VV; Kiselyov, AS; Titov, IY; Sagamanova, IK; Ikizalp, NN; Chernysheva, NB; Tsyganov, DV; Konyushkin, LD; Firgang, SI; Semenov, RV; Karmanova, IB; Raihstat, MM; Semenova, MN,期刊:Journal of natural products, 页码:1796-1802 , 文章类型: Article,,卷期:2010年73-11]
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- Structure and Cytotoxicity of Diterpenoids from Isodon eriocalyx
[作者:Li, XN; Pu, JX; Du, X; Lou, LG; Li, LM; Huang, SX; Zhao, B; Zhang, M; He, F; Luo, XA; Xiao, WL; Sun, HD,期刊:Journal of natural products, 页码:1803-1809 , 文章类型: Article,,卷期:2010年73-11]
- A new ent-atisanoid, eriocatisin A (1), six new ent-abietanoids, eriocasins B-E (2-4, 7), 3-acetyleriocasin C (5), and 3 beta-acetoxyeriocasin D (6), and seven new ent-kauranoids, maoesins A-F (8, 10-14) and 3 alpha-acet...
- Lagunamides A and B: Cytotoxic and Antimalarial Cyclodepsipeptides from the Marine Cyanobacterium Lyngbya majuscula
[作者:Tripathi, A; Puddick, J; Prinsep, MR; Rottmann, M; Tan, LT,期刊:Journal of natural products, 页码:1810-1814 , 文章类型: Article,,卷期:2010年73-11]
- Lagunamides A (1) and B (2) are new cyclic depsipeptides isolated from the marine cyanobacterium Lyngbya majuscula obtained from Pulau Hantu Besar, Singapore. The planar structural characterization of these molecules was...
- Norlignans, Acylphloroglucinols, and a Dimeric Xanthone from Hypericum chinense
[作者:Wang, W; Zeng, YH; Osman, K; Shinde, K; Rahman, M; Gibbons, S; Mu, Q,期刊:Journal of natural products, 页码:1815-1820 , 文章类型: Article,,卷期:2010年73-11]
- Two new norlignans, hyperiones A (1) and B (2), three new acylphloroglucinols, aspidinol C (3) and hyperaspidinols A (5) and B (6), the known compound aspidinol D (4), and the symmetrical dimeric xanthone hyperidixanthon...
- Antibacterial Prenylated Acylphloroglucinols from the Fern Elaphoglossum yungense
[作者:Socolsky, C; Arena, ME; Asakawa, Y; Bardon, A,期刊:Journal of natural products, 页码:1751-1755 , 文章类型: Article,,卷期:2010年73-11]
- Seven new prenylated acylphloroglucinols, yungensins A G, were isolated from the diethyl ether extract of the scaly rhizomes and roots of an Argentine collection of the fern Elaphoglossum yungense. All the compounds cont...
- Camphoratins A-J, Potent Cytotoxic and Anti-inflammatory Triterpenoids from the Fruiting Body of Taiwanofungus camphoratus
[作者:Wu, SJ; Leu, YL; Chen, CH; Chao, CH; Shen, DY; Chan, HH; Lee, EJ; Wu, TS; Wang, YH; Shen, YC; Qian, KD; Bastow, KF; Lee, KH,期刊:Journal of natural products, 页码:1756-1762 , 文章类型: Article,,卷期:2010年73-11]
- Ten new triterpenoids, camphoratins A-J (1-10), along with 12 known compounds were isolated from the fruiting body of Taiwanofungus camphoratus. Their structures were established by spectroscopic analysis and chemical me...
- Ipomotaosides A-D, Resin Glycosides from the Aerial Parts of Ipomoea batatas and Their Inhibitory Activity against COX-1 and COX-2
[作者:Yoshikawa, K; Yagi, C; Hama, H; Tanaka, M; Arihara, S; Hashimoto, T,期刊:Journal of natural products, 页码:1763-1766 , 文章类型: Article,,卷期:2010年73-11]
- Four new resin glycosides, namely, ipomotaosides A-D (1-4), were isolated from the dried aerial parts of Ipomoea batatas. The structures of 1-4 were elucidated by analysis of their spectroscopic data and by chemical deri...
- Inhibition of Melanogenesis and Oxidation by Protocatechuic Acid from Origanum vulgare (Oregano)
[作者:Chou, TH; Ding, HY; Lin, RJ; Liang, JY; Liang, CH,期刊:Journal of natural products, 页码:1767-1774 , 文章类型: Article,,卷期:2010年73-11]
- Antioxidant and antimelanogenesis activities of protocatechuic acid (1) from Origanum vulgare (oregano) were investigated. The antioxidative capacity of 1 was confirmed from its free-radical-scavenging activities, inhibi...
- Benzophenones and Biflavonoids from Rheedia edulis
[作者:Acuna, UM; Figueroa, M; Kavalier, A; Jancovski, N; Basile, MJ; Kennelly, EJ,期刊:Journal of natural products, 页码:1775-1779 , 文章类型: Article,,卷期:2010年73-11]
- Two new polyisoprenylated benzophenones, 32-hydroxy-ent-guttiferone M (1) and 6-epi-guttiferone J (2), along with seven known compounds, 6-epi-clusianone (3), guttiferone A (4), xanthochymol (5), guttiferone E (6), isoxa...
- Use of Experimental Design for the Optimization of the Production of New Secondary Metabolites by Two Penicillium Species
[作者:Pimenta, EF; Vita-Marques, AM; Tininis, A; Seleghim, MHR; Sette, LD; Veloso, K; Ferreira, AG; Williams, DE; Patrick, BO; Dalisay, DS; Andersen, RJ; Berlinck, RGS,期刊:Journal of natural products, 页码:1821-1832 , 文章类型: Article,,卷期:2010年73-11]
- A fractional factorial design approach has been used to enhance secondary metabolite production by two Penicillium strains. The method was initially used to improve the production of bioactive extracts as a whole and sub...
- Phytochemical Investigations of Stemona curtisii and Synthetic Studies on Stemocurtisine Alkaloids
[作者:Chaiyong, S; Jatisatienr, A; Mungkornasawakul, P; Sastraruji, T; Pyne, SG; Ung, AT; Urathamakul, T; Lie, W,期刊:Journal of natural products, 页码:1833-1838 , 文章类型: Article,,卷期:2010年73-11]
- The isolation of two new Stemona alkaloids, 1-hydroxyprotostemonine and stemocurtisine N-oxide, and a new benzofuran, stemofuran L, from the root extracts of Stemona curtisii is reported. The major known alkaloids from t...
- Triterpenes from Garcia parviflora. Cytotoxic Evaluation of Natural and Semisynthetic Friedelanes
[作者:Reyes, BM; Ramirez-Apan, MT; Toscano, RA; Delgado, G,期刊:Journal of natural products, 页码:1839-1845 , 文章类型: Article,,卷期:2010年73-11]
- Three new friedelane-type triterpenes, 1,2-dehydro-2,3-secofriedelan-3-oic acid (1), 1 beta-hydroxyfriedelin (2), and 3 beta-hydroxyfriedelan-23-oic acid (3), and the known compounds friedelin-3,4-lactone (4), acetyl ale...
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