- Activation of human monocytes by a formyl peptide receptor 2-derived pepducin
[作者:Lee, HY; Kim, SD; Shim, JW; Kim, HJ; Kwon, JY; Kim, JM; Baek, SH; Park, JS; Bae, YS,期刊:FEBS Letters, 页码:4102-4108 , 文章类型: Article,,卷期:2010年584-18]
- We synthesized and investigated the effect of formyl peptide receptor 2 (FPR2)-derived pepducins in human monocytes. The FPR2-based cell-penetrating lipopeptide, "pepducin" (F2pal-16), stimulated intracellular calcium in...
- Development of a cell-free system reveals an oxygen-labile step in the maturation of [NiFe]-hydrogenase 2 of Escherichia coli
[作者:Soboh, B; Kruger, S; Kuhns, M; Pinske, C; Lehmann, A; Sawers, RG,期刊:FEBS Letters, 页码:4109-4114 , 文章类型: Article,,卷期:2010年584-18]
- By combining extracts from strains lacking genes encoding either the maturation enzymes or the large subunits of hydrogenases 1, 2 and 3 we could reconstitute in vitro under strictly anaerobic conditions 10-15% of the hy...
- MicroRNA-24 targeting RNA-binding protein DND1 in tongue squamous cell carcinoma
[作者:Liu, XQ; Wang, AX; Heidbreder, CE; Jiang, L; Yu, JS; Kolokythas, A; Huang, L; Dai, Y; Zhou, XF,期刊:FEBS Letters, 页码:4115-4120 , 文章类型: Article,,卷期:2010年584-18]
- Deregulations of microRNA have been frequently observed in tongue squamous cell carcinoma (TSCC), but their roles in tumorigenesis are not entirely clear. Here, we reported the up-regulation of miR-24 in TSCC. MiR-24 up-...
- The full-length isoform of the mouse pleckstrin homology domain-interacting protein (PHIP) is required for postnatal growth
[作者:Li, SA; Francisco, AB; Han, CC; Pattabiraman, S; Foote, MR; Giesy, SL; Wang, C; Schimenti, JC; Boisclair, YR; Long, QM,期刊:FEBS Letters, 页码:4121-4127 , 文章类型: Article,,卷期:2010年584-18]
- PHIP was isolated as an insulin receptor substrate 1 (IRS-1) interacting protein. To date, the physiological roles of PHIP remain unknown. Here we show that mice lacking PHIP1, the full-length isoform of PHIP, are born a...
- Crystal structure of Bifidobacterium Longum phosphoketolase; key enzyme for glucose metabolism in Bifidobacterium
[作者:Takahashi, K; Tagami, U; Shimba, N; Kashiwagi, T; Ishikawa, K; Suzuki, E,期刊:FEBS Letters, 页码:3855-3861 , 文章类型: Article,,卷期:2010年584-18]
The crystal structure of Bifidobacterium longum phosphoketolase, a thiamine diphosphate (TPP) dependent enzyme, has been determined at 2.2 angstrom resolution. The enzyme is a dimer with the active sites located at th...
- Isolation of a point-mutated p47 lacking binding affinity to p97ATPase
[作者:Kaneko, Y; Tamura, K; Totsukawa, G; Kondo, H,期刊:FEBS Letters, 页码:3873-3877 , 文章类型: Article,,卷期:2010年584-18]
- p47, a p97-binding protein, functions in Golgi membrane fusion together with p97 and VCIP135, another p97-binding protein. We have succeeded in creating p47 with a point mutation, F253S, which lacks p97-binding affinity....
- Nuclear EGFR shuttling induced by ionizing radiation is regulated by phosphorylation at residue Thr654
[作者:Dittmann, K; Mayer, C; Fehrenbacher, B; Schaller, M; Kehlbach, R; Rodemann, HP,期刊:FEBS Letters, 页码:3878-3884 , 文章类型: Article,,卷期:2010年584-18]
- Nuclear localisation of EGFR is associated with treatment resistance of tumor cells. The aim of this study was to identify molecular targets to block nuclear shuttling of EGFR. Mutation of Thr654, located within the puta...
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