- UV-induced interaction between p38 MAPK and p53 serves as a molecular switch in determining cell fate
[作者:Gong, XW; Liu, AH; Ming, XY; Deng, P; Jiang, Y,期刊:FEBS Letters, 页码:4711-4716 , 文章类型: Article,,卷期:2010年584-23]
- p53 plays a fundamental role in the maintenance of genome integrity after DNA damage, deciding whether cells repair and live, or die. However, the rules that govern its choice are largely undiscovered. Here we show that ...
- Characterization of GmCaMK1, a member of a soybean calmodulin-binding receptor-like kinase family
[作者:DeFalco, TA; Chiasson, D; Munro, K; Kaiser, BN; Snedden, WA,期刊:FEBS Letters, 页码:4717-4724 , 文章类型: Article,,卷期:2010年584-23]
- Calmodulin(CaM)-regulated protein phosphorylation forms an important component of Ca2+ signaling in animals but is less understood in plants. We have identified a CaM-binding receptor-like kinase from soybean nodules, Gm...
- Consequences of IkappaB alpha hydroxylation by the factor inhibiting HIF (FIH)
[作者:Devries, IL; Hampton-Smith, RJ; Mulvihill, MM; Alverdi, V; Peet, DJ; Komives, EA,期刊:FEBS Letters, 页码:4725-4730 , 文章类型: Article,,卷期:2010年584-23]
- The factor inhibiting HIF-1 ( FIH-1) hydroxylates many ankyrin repeat-containing proteins including I kappa B alpha. It is widely speculated that hydroxylation of I kappa B alpha has functional consequences, but the effe...
- Per3, a circadian gene, is required for Chk2 activation in human cells
[作者:Im, JS; Jung, BH; Kim, SE; Lee, KH; Lee, JK,期刊:FEBS Letters, 页码:4731-4734 , 文章类型: Article,,卷期:2010年584-23]
- PER3 is a member of the PERIOD genes, but does not play essential roles in the circadian clock. Depletion of Per3 by siRNA almost completely abolished activation of checkpoint kinase 2 (Chk2) after inducing DNA damage in...
- Identification of an intracellular microdomain of the P2X(7) receptor that is crucial in basolateral membrane targeting in epithelial cells
[作者:Bradley, HJ; Liu, X; Collins, V; Owide, J; Goli, GR; Smith, M; Surprenant, A; White, SJ; Jiang, LH,期刊:FEBS Letters, 页码:4740-4744 , 文章类型: Article,,卷期:2010年584-23]
- We investigated membrane targeting of the P2X(7) receptor (P2X(7)R) in polarized epithelial cells using immunofluorescent confocal imaging. The wild-type receptor was targeted to the basolateral membrane, independently o...
- Feedback regulation of Ras2 guanine nucleotide exchange factor (Ras2-GEF) activity of Cdc25p by Cdc25p phosphorylation in the yeast Saccharomyces cerevisiae
[作者:Dong, JA; Zhang, AL; Bai, XJ; Zhao, HS; Hu, Y,期刊:FEBS Letters, 页码:4745-4750 , 文章类型: Article,,卷期:2010年584-23]
- Ras-GEF Cdc25p has been found to be hyperphosphorylated upon glucose addition. This work provides evidence indicating that PKA activity positively regulates the degree of Cdc25p phosphorylation, and that the intracellula...
- An efflux pump is involved in secretion of newly synthesized siderophore by Pseudomonas aeruginosa
[作者:Hannauer, M; Yeterian, E; Martin, LW; Lamont, IL; Schalk, IJ,期刊:FEBS Letters, 页码:4751-4755 , 文章类型: Article,,卷期:2010年584-23]
- Pseudomonas aeruginosa secretes the fluorescent siderophore, pyoverdine (PVD), to enable iron acquisition. Epifluorescence microscopy and cellular fractionation were used to investigate the role of an efflux pump, PvdRT-...
- Intraerythrocytic stages of Plasmodium falciparum biosynthesize menaquinone
[作者:Tonhosolo, R; Gabriel, HB; Matsumura, MY; Cabral, FJ; Yamamoto, MM; D'Alexandri, FL; Sussmann, RAC; Belmonte, R; Peres, VJ; Crick, DC; Wunderlich, G; Kimura, EA; Katzin, AM,期刊:FEBS Letters, 页码:4761-4768 , 文章类型: Article,,卷期:2010年584-23]
- Herein, we show that intraerythrocytic stages of Plasmodium falciparum have an active pathway for biosynthesis of menaquinone. Kinetic assays confirmed that plasmodial menaquinone acts at least in the electron transport....
- Phylogenetic analysis and evolution of aromatic amino acid hydroxylase
[作者:Cao, J; Shi, F; Liu, XG; Huang, GA; Zhou, M,期刊:FEBS Letters, 页码:4775-4782 , 文章类型: Article,,卷期:2010年584-23]
- A study was performed to investigate the phylogenetic relationship among AAAH members and to statistically evaluate sequence conservation and functional divergence. In total, 161 genes were identified from 103 species. P...
- Functional analysis of propeptide as an intramolecular chaperone for in vivo folding of subtilisin nattokinase
[作者:Jia, Y; Liu, H; Bao, W; Weng, MZ; Chen, W; Cai, YJ; Zheng, ZL; Zou, GL,期刊:FEBS Letters, 页码:4789-4796 , 文章类型: Article,,卷期:2010年584-23]
- Here, we show that during in vivo folding of the precursor, the propeptide of subtilisin nattokinase functions as an intramolecular chaperone (IMC) that organises the in vivo folding of the subtilisin domain. Two residue...
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