- Scanning probe block copolymer lithography
[作者:Chai, JA; Huo, FW; Zheng, ZJ; Giam, LR; Shim, W; Mirkin, CA,期刊:Proceedings of the National Academy of Sciences of the United States of America, 页码:20202-20206 , 文章类型: Article,,卷期:2010年107-47]
- Integration of individual nanoparticles into desired spatial arrangements over large areas is a prerequisite for exploiting their unique electrical, optical, and chemical properties. However, positioning single sub-10-nm...
- Postdetonation nuclear debris for attribution
[作者:Fahey, AJ; Zeissler, CJ; Newbury, DE; Davis, J; Lindstrom, RM,期刊:Proceedings of the National Academy of Sciences of the United States of America, 页码:20207-20212 , 文章类型: Article,,卷期:2010年107-47]
- On the morning of July 16, 1945, the first atomic bomb was exploded in New Mexico on the White Sands Proving Ground. The device was a plutonium implosion device similar to the device that destroyed Nagasaki, Japan, on Au...
- Antibodies protect against intracellular bacteria by Fc receptor-mediated lysosomal targeting
[作者:Joller, N; Weber, SS; Muller, AJ; Sporri, R; Selchow, P; Sander, P; Hilbi, H; Oxenius, A,期刊:Proceedings of the National Academy of Sciences of the United States of America, 页码:20441-20446 , 文章类型: Article,,卷期:2010年107-47]
- The protective effect of antibodies (Abs) is generally attributed to neutralization or complement activation. Using Legionella pneumophila and Mycobacterium bovis bacillus Calmette-Guerin as a model, we discovered an add...
- Detection of oxygen isotopic anomaly in terrestrial atmospheric carbonates and its implications to Mars
[作者:Shaheen, R; Abramian, A; Horn, J; Dominguez, G; Sullivan, R; Thiemens, MH,期刊:Proceedings of the National Academy of Sciences of the United States of America, 页码:20213-20218 , 文章类型: Article,,卷期:2010年107-47]
- The debate of life on Mars centers around the source of the globular, micrometer-sized mineral carbonates in the ALH84001 meteorite; consequently, the identification of Martian processes that form carbonates is critical....
- Visualizing electron rearrangement in space and time during the transition from a molecule to atoms
[作者:Li, W; Jaron-Becker, AA; Hogle, CW; Sharma, V; Zhou, XB; Becker, A; Kapteyn, HC; Murnane, MM,期刊:Proceedings of the National Academy of Sciences of the United States of America, 页码:20219-20222 , 文章类型: Article,,卷期:2010年107-47]
- Imaging and controlling reactions in molecules and materials at the level of electrons is a grand challenge in science, relevant to our understanding of charge transfer processes in chemistry, physics, and biology, as we...
- Role of antigen persistence and dose for CD4(+) T-cell exhaustion and recovery
[作者:Han, S; Asoyan, A; Rabenstein, H; Nakano, N; Obst, R,期刊:Proceedings of the National Academy of Sciences of the United States of America, 页码:20453-20458 , 文章类型: Article,,卷期:2010年107-47]
- It is currently not understood how some chronic infections exhaust antigen-specific T cells over time and which pathogen components contribute to exhaustion. Here, we dissected the behavior of primed CD4(+) T cells expos...
- Schistosoma mansoni triggers Dectin-2, which activates the Nlrp3 inflammasome and alters adaptive immune responses
[作者:Ritter, M; Gross, O; Kays, S; Ruland, J; Nimmerjahn, F; Saijo, S; Tschopp, J; Layland, LE; da Costa, CP,期刊:Proceedings of the National Academy of Sciences of the United States of America, 页码:20459-20464 , 文章类型: Article,,卷期:2010年107-47]
- The propensity of helminths, such as schistosomes, to immuno-modulate the host's immune system is an essential aspect of their survival. Previous research has demonstrated how soluble schistosomal egg antigens (SEA) damp...
- Ubiquitination regulates MHC class II-peptide complex retention and degradation in dendritic cells
[作者:Walseng, E; Furuta, K; Bosch, B; Weih, KA; Matsuki, Y; Bakke, O; Ishido, S; Roche, PA,期刊:Proceedings of the National Academy of Sciences of the United States of America, 页码:20465-20470 , 文章类型: Article,,卷期:2010年107-47]
- The expression and turnover of MHC class II-peptide complexes (pMHC-II) on the surface of dendritic cells (DCs) is essential for their ability to activate CD4 T cells efficiently. The half-life of surface pMHC-II is sign...
- Chronology of the Grotte du Renne (France) and implications for the context of ornaments and human remains within the Chatelperronian
[作者:Higham, T; Jacobi, R; Julien, M; David, F; Basell, L; Wood, R; Davies, W; Ramsey, CB,期刊:Proceedings of the National Academy of Sciences of the United States of America, 页码:20234-20239 , 文章类型: Article,,卷期:2010年107-47]
- There is extensive debate concerning the cognitive and behavioral adaptation of Neanderthals, especially in the period when the earliest anatomically modern humans dispersed into Western Europe, around 35,000-40,000 B. P...
- Stem cell-like micro-RNA signature driven by Myc in aggressive liver cancer
[作者:Cairo, S; Wang, YP; de Reynies, A; Duroure, K; Dahan, J; Redon, MJ; Fabre, M; McClelland, M; Wang, XW; Croce, CM; Buendia, MA,期刊:Proceedings of the National Academy of Sciences of the United States of America, 页码:20471-20476 , 文章类型: Article,,卷期:2010年107-47]
- Myc activation has been implicated in the pathogenesis of hepatoblastoma (HB), a rare embryonal neoplasm derived from liver progenitor cells. Here, microRNA (miR) expression profiling of 65 HBs evidenced differential pat...
- NADPH oxidase-mediated reactive oxygen species production activates hypoxia-inducible factor-1 (HIF-1) via the ERK pathway after hyperthermia treatment
[作者:Moon, EJ; Sonveaux, P; Porporato, PE; Danhier, P; Gallez, B; Batinic-Haberle, I; Nien, YC; Schroeder, T; Dewhirst, MW,期刊:Proceedings of the National Academy of Sciences of the United States of America, 页码:20477-20482 , 文章类型: Article,,卷期:2010年107-47]
- Hyperthermia (HT) is a strong adjuvant treatment with radiotherapy and chemotherapy because it causes tumor reoxygenation. However, the detailed molecular mechanisms of how HT enhances tumor oxygenation have not been elu...
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