- Romiplostim or Standard of Care in Patients with Immune Thrombocytopenia
[作者:Kuter, DJ; Rummel, M; Boccia, R; Macik, BG; Pabinger, I; Selleslag, D; Rodeghiero, F; Chong, BH; Wang, XN; Berger, DP,期刊:New England Journal of Medicine, 页码:1889-1899 , 文章类型: Article,,卷期:2010年363-20]
- Background: Romiplostim, a thrombopoietin mimetic, increases platelet counts in patients with immune thrombocytopenia, with few adverse effects.Methods: In this open-label, 52-week study, we randomly assigned 234 adult p...
- Dietary Intervention in Infancy and Later Signs of Beta-Cell Autoimmunity
[作者:Knip, M; Virtanen, SM; Seppa, K; Ilonen, J; Savilahti, E; Vaarala, O; Reunanen, A; Teramo, K; Hamalainen, A; Paronen, J; Dosch, H; Hakulinen, T; Akerblom, HK,期刊:New England Journal of Medicine, 页码:1900-1908 , 文章类型: Article,,卷期:2010年363-20]
- Background: Early exposure to complex dietary proteins may increase the risk of beta-cell autoimmunity and type 1 diabetes in children with genetic susceptibility. We tested the hypothesis that supplementing breast milk ...
- Clopidogrel with or without Omeprazole in Coronary Artery Disease
[作者:Bhatt, DL; Cryer, BL; Contant, CF; Cohen, M; Lanas, A; Schnitzer, TJ; Shook, TL; Lapuerta, P; Goldsmith, MA; Laine, L; Scirica, BM; Murphy, SA; Cannon, CP,期刊:New England Journal of Medicine, 页码:1909-1917 , 文章类型: Article,,卷期:2010年363-20]
- Background: Gastrointestinal complications are an important problem of antithrombotic therapy. Proton-pump inhibitors (PPIs) are believed to decrease the risk of such complications, though no randomized trial has proved ...
- Stem-Cell Gene Therapy for the Wiskott-Aldrich Syndrome
[作者:Boztug, K; Schmidt, M; Schwarzer, A; Banerjee, PP; Diez, IA; Dewey, RA; Bohm, M; Nowrouzi, A; Ball, CR; Glimm, H; Naundorf, S; Kuhlcke, K; Blasczyk, R; Kondratenko, I; Marodi, L; Orange, JS; von Kalle, C; Klein, C,期刊:New England Journal of Medicine, 页码:1918-1927 , 文章类型: Article,,卷期:2010年363-20]
- The Wiskott-Aldrich syndrome (WAS) is an X-linked recessive primary immunodeficiency disorder associated with thrombocytopenia, eczema, and autoimmunity. We treated two patients who had this disorder with a transfusion o...
- Effect of a Comprehensive Surgical Safety System on Patient Outcomes
[作者:de Vries, EN; Prins, HA; Crolla, RMPH; den Outer, AJ; van Andel, G; van Helden, SH; Schlack, WS; van Putten, MA; Gouma, DJ; Dijkgraaf, MGW; Smorenburg, SM; Boermeester, MA,期刊:New England Journal of Medicine, 页码:1928-1937 , 文章类型: Article,,卷期:2010年363-20]
- Background: Adverse events in patients who have undergone surgery constitute a large proportion of iatrogenic illnesses. Most surgical safety interventions have focused on the operating room. Since more than half of all ...
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