- The Protein Circular Dichroism Data Bank, A Web-Based Site for Access to Circular Dichroism Spectroscopic Data
[作者：Whitmore, L; Woollett, B; Miles, AJ; Janes, RW; Wallace, BA,期刊：Structure, 页码：1267-1269 , 文章类型： Article，,卷期：2010年18-10]
- The Protein Circular Dichroism Data Bank (PCDDB) is a newly released resource for structural biology. It is a web-accessible (http://pcddb.cryst.bbk.ac.uk) data bank for circular dichroism (CD) and synchrotron radiation ...
- The Structure of the Talin/Integrin Complex at a Lipid Bilayer: An NMR and MD Simulation Study
[作者：Kalli, AC; Wegener, KL; Goult, BT; Anthis, NJ; Campbell, ID; Sansom, MSP,期刊：Structure, 页码：1280-1288 , 文章类型： Article，,卷期：2010年18-10]
- Integrins are cell surface receptors crucial for cell migration and adhesion. They are activated by interactions of the talin head domain with the membrane surface and the integrin 3 cytoplasmic tail. Here, we use coarse...
- The Structure of the Talin Head Reveals a Novel Extended Conformation of the FERM Domain
[作者：Elliott, PR; Goult, BT; Kopp, PM; Bate, N; Grossmann, JG; Roberts, GCK; Critchley, DR; Barsukov, IL,期刊：Structure, 页码：1289-1299 , 文章类型： Article，,卷期：2010年18-10]
- FERM domains are found in a diverse superfamily of signaling and adaptor proteins at membrane interfaces. They typically consist of three separately folded domains (F1, F2, F3) in a compact cloverleaf structure. The crys...
- Cryo-EM Analysis Reveals New Insights into the Mechanism of Action of Pyruvate Carboxylase
[作者：Lasso, G; Yu, LPC; Gil, D; Xiang, S; Tong, LA; Valle, M,期刊：Structure, 页码：1300-1310 , 文章类型： Article，,卷期：2010年18-10]
- Pyruvate carboxylase (PC) is a conserved multifunctional enzyme linked to important metabolic diseases. PC homotetramer is arranged in two layers with two opposing monomers per layer. Cryo-EM explores the conformational ...
- Structural Analysis of the Interaction between Dishevelled2 and Clathrin AP-2 Adaptor, A Critical Step in Noncanonical Wnt Signaling
[作者：Yu, AA; Xing, Y; Harrison, SC; Kirchhausen, T,期刊：Structure, 页码：1311-1320 , 文章类型： Article，,卷期：2010年18-10]
- Wnt association with its receptor, Frizzled (Fz), and recruitment by the latter of an adaptor, Dishevelled (Dvl), initiates signaling through at least two distinct pathways ("canonical" and "noncanonical"). Endocytosis a...
- Hydrogen/Deuterium Exchange Reveals Distinct Agonist/Partial Agonist Receptor Dynamics within Vitamin D Receptor/Retinoid X Receptor Heterodimer
[作者：Zhang, J; Chalmers, MJ; Stayrook, KR; Burris, LL; Garcia-Ordonez, RD; Pascal, BD; Burris, TP; Dodge, JA; Griffin, PR,期刊：Structure, 页码：1332-1341 , 文章类型： Article，,卷期：2010年18-10]
- Regulation of nuclear receptor (NR) activity is driven by alterations in the conformational dynamics of the receptor upon ligand binding. Previously, we demonstrated that hydrogen/deuterium exchange (HDX) can be applied ...
- Structural Basis for Ligand Recognition and Activation of RAGE
[作者：Koch, M; Chitayat, S; Dattilo, BM; Schiefner, A; Diez, J; Chazin, WJ; Fritz, G,期刊：Structure, 页码：1342-1352 , 文章类型： Article，,卷期：2010年18-10]
- The receptor for advanced glycation end products (RAGE) is a pattern recognition receptor involved in inflammatory processes and is associated with diabetic complications, tumor outgrowth, and neurodegenerative disorders...
- Structural Insight into Serine Protease Rv3671c that Protects M. tuberculosis from Oxidative and Acidic Stress
[作者：Biswas, T; Sma, J; Vandal, O; Odaira, T; Deng, H; Ehrt, S; Tsodikov, OV,期刊：Structure, 页码：1353-1363 , 文章类型： Article，,卷期：2010年18-10]
- Rv3671c, a putative serine protease, is crucial for persistence of Mycobacterium tuberculosis in the hostile environment of the phagosome. We show that Rv3671c is required for M. tuberculosis resistance to oxidative stre...
- Structural Insights into RNA Recognition by the Alternate-Splicing Regulator CUG-Binding Protein 1
[作者：Teplova, M; Song, J; Gaw, HY; Teplov, A; Patel, DJ,期刊：Structure, 页码：1364-1377 , 文章类型： Article，,卷期：2010年18-10]
- CUG-binding protein 1 (CUGBP1) regulates multiple aspects of nuclear and cytoplasmic mRNA processing, with implications for onset of myotonic dystrophy. CUGBP1 harbors three RRM domains and preferentially targets UGU-ric...
- Solution NMR Investigation of the CD95/FADD Homotypic Death Domain Complex Suggests Lack of Engagement of the CD95 C Terminus
[作者：Esposito, D; Sankar, A; Morgner, N; Robinson, CV; Rittinger, K; Driscoll, PC,期刊：Structure, 页码：1378-1390 , 文章类型： Article，,卷期：2010年18-10]
- We have addressed complex formation between the death domain (DD) of the death receptor CD95 (Fas/APO-1) with the DD of immediate adaptor protein FADD using nuclear magnetic resonance (NMR) spectroscopy, mass spectrometr...
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