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  • XLF Regulates Filament Architecture of the XRCC4.Ligase IV Complex
    [作者:Hammel, M; Yu, YP; Fang, SJ; Lees-Miller, SP; Tainer, JA,期刊:Structure, 页码:1431-1442 , 文章类型: Article,,卷期:2010年18-11]
  • DNA ligase IV (LigIV) is critical for non homologous end joining (NHEJ), the major DNA double-strand break (DSB) repair pathway in human cells, and LigIV activity is regulated by XRCC4 and XLF (XRCC4-like factor) interac...