- Distinct Regions of Human eIF3 Are Sufficient for Binding to the HCV IRES and the 40S Ribosomal Subunit
[作者：Cai, Q; Todorovic, A; Andaya, A; Gao, JY; Leary, JA; Cate, JHD,期刊：Journal of Molecular Biology, 页码：185-196 , 文章类型： Article，,卷期：2010年403-2]
- Translation of the hepatitis C virus (HCV) genomic RNA initiates from an internal ribosome entry site (IRES) in its 5 ' untranslated region and requires a minimal subset of translation initiation factors to occur, namely...
- The Metalloregulatory Zinc Site in Streptococcus pneumoniae AdcR, a Zinc-activated MarR Family Repressor
[作者：Reyes-Caballero, H; Guerra, AJ; Jacobsen, FE; Kazmierczak, KM; Cowart, D; Koppolu, UMK; Scott, RA; Winkler, ME; Giedroc, DP,期刊：Journal of Molecular Biology, 页码：197-216 , 文章类型： Article，,卷期：2010年403-2]
- Streptococcus pneumoniae D39 AdcR (adhesin competence repressor) is the first metal-sensing member of the MarR (multiple antibiotic resistance repressor) family to be characterized. Expression profiling with a Delta adcR...
- Structural Characterization of Protein-Protein Complexes by Integrating Computational Docking with Small-angle Scattering Data
[作者：Pons, C; D'Abramo, M; Svergun, DI; Orozcoz, M; Bernado, P; Fernandez-Recio, J,期刊：Journal of Molecular Biology, 页码：217-230 , 文章类型： Article，,卷期：2010年403-2]
- X-ray crystallography and NMR can provide detailed structural information of protein protein complexes, but technical problems make their application challenging in the high-throughput regime. Other methods such as small...
- Conserved Hydrophobic Clusters on the Surface of the Caf1A Usher C-Terminal Domain Are Important for F1 Antigen Assembly
[作者：Dubnovitsky, AP; Duck, Z; Kersley, JE; Hard, T; MacIntyre, S; Knight, SD,期刊：Journal of Molecular Biology, 页码：243-259 , 文章类型： Article，,卷期：2010年403-2]
- The outer membrane usher protein Caf1A of the plague pathogen Yersinia pestis is responsible for the assembly of a major surface antigen, the F1 capsule. The F1 capsule is mainly formed by thin linear polymers of CaF1 (c...
- Crystal Structure of gamma-Hexachlorocyclohexane Dehydrochlorinase LinA from Sphingobium japonicum UT26
[作者：Okai, M; Kubota, K; Fukuda, M; Nagata, Y; Negata, K; Tanokura, M,期刊：Journal of Molecular Biology, 页码：260-269 , 文章类型： Article，,卷期：2010年403-2]
LinA from Sphingobium japonicum UT26 catalyzes two steps of dehydrochlorination from gamma hexachlorocyclohexane (HCH) to 1,3,4,6-tetrachloro-1,4-cyclohexadiene via gamma-pentachlorocyclohexene. We determined the crys...
- TolA Modulates the Oligomeric Status of YbgF in the Bacterial Periplasm
[作者：Krachler, AM; Sharma, A; Cauldwell, A; Papadakos, G; Kleanthous, C,期刊：Journal of Molecular Biology, 页码：270-285 , 文章类型： Article，,卷期：2010年403-2]
- The trans-envelope Tol complex of Gram-negative bacteria is recruited to the septation apparatus during cell division where it is involved in stabilizing the outer membrane. The last gene in the tol operon, ybgF, is high...
- Determinants of Substrate Binding and Protonation in the Flavoenzyme Xenobiotic Reductase A
[作者：Spiegelhauer, O; Werther, T; Mende, S; Knauer, SH; Dobbek, H,期刊：Journal of Molecular Biology, 页码：286-298 , 文章类型： Article，,卷期：2010年403-2]
- Xenobiotic reductase A (XenA) from Pseudomonas putida 86 catalyzes the NAD(P)H-dependent reduction of various alpha,beta-unsaturated carbonyl compounds and is a member of the old yellow enzyme family. The reaction of Xen...
- Conformational Exchange Is Critical for the Productivity of an Oxidative Folding Intermediate with Buried Free Cysteines
[作者：Gross, G; Gallopin, M; Vandame, M; Couprie, J; Stura, E; Zinn-Justin, S; Drevet, P,期刊：Journal of Molecular Biology, 页码：299-312 , 文章类型： Article，,卷期：2010年403-2]
- Much has been learned about the folding of proteins from comparative studies of the folding of proteins that are related in sequence and structure. Observation of the effects of mutations helps account for sequence-speci...
- Carboxyl pK(a) Values and Acid Denaturation of BBL
[作者：Arbely, E; Rutherford, TJ; Neuweiler, H; Sharpe, TD; Ferguson, N; Fersht, AR,期刊：Journal of Molecular Biology, 页码：313-327 , 文章类型： Article，,卷期：2010年403-2]
- The protein BBL undergoes structural transitions and acid denaturation between pH 1.2 and 8.0. Using NMR spectroscopy, we measured the pK(a) values of all the carboxylic residues in this pH range. We employed C-13 direct...
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