- Structural Analysis of the Interactions Between Hsp70 Chaperones and the Yeast DNA Replication Protein Orc4p
[作者:Moreno-del Alamo, M; Sanchez-Gorostiaga, A; Serrano, AM; Prieto, A; Cuellar, J; Martin-Benito, J; Valpuesta, JM; Giraldo, R,期刊:Journal of Molecular Biology, 页码:24-39 , 文章类型: Article,,卷期:2010年403-1]
- Hsp70 chaperones, besides their role in assisting protein folding, are key modulators of protein disaggregation, being consistently found as components of most macromolecular assemblies isolated in proteome-wide affinity...
- Solution Structure of the Heterotrimeric Complex between the Interaction Domains of RFX5 and RFXAP from the RFX Gene Regulatory Complex
[作者:Laird, KM; Briggs, LL; Boss, JM; Summers, MF; Garvie, CW,期刊:Journal of Molecular Biology, 页码:40-51 , 文章类型: Article,,卷期:2010年403-1]
- The mammalian immune response is mediated by a heterotetrameric transcriptional control complex, called regulatory factor X (RFX), that regulates the expression of major histocompatibility complex class H genes. RFX comp...
- Diversity of Bisubstrate Binding Modes of Adenosine Analogue-Oligoarginine Conjugates in Protein Kinase A and Implications for Protein Substrate Interactions
[作者:Pflug, A; Rogozina, J; Lavogina, D; Enkvist, E; Uri, A; Engh, RA; Bossemeyer, D,期刊:Journal of Molecular Biology, 页码:66-77 , 文章类型: Article,,卷期:2010年403-1]
- Crystal structures of the catalytic subunit a of cAMP-dependent protein kinase (PKAc) with three adenosine analogue-oligoarginine conjugates (ARCs) are presented. The rationally designed ARCs include moieties that, in co...
- The Switch that Does Not Flip: The Blue-Light Receptor YtvA from Bacillus subtilis Adopts an Elongated Dimer Conformation Independent of the Activation State as Revealed by a Combined AUC and SAXS Study
[作者:Jurk, M; Dorn, M; Kikhney, A; Svergun, D; Gartner, W; Schmieder, P,期刊:Journal of Molecular Biology, 页码:78-87 , 文章类型: Article,,卷期:2010年403-1]
- Photoreceptors play an important role in plants and bacteria by converting extracellular stimuli into intracellular signals. One distinct class are the blue-light-sensitive phototropins harboring a light oxygen voltage (...
- Optimal Packaging of FIV Genomic RNA Depends upon a Conserved Long-range Interaction and a Palindromic Sequence within gag
[作者:Rizvi, TA; Kenyon, JC; Ali, J; Aktar, SJ; Phillip, PS; Ghazawi, A; Mustafa, F; Lever, AML,期刊:Journal of Molecular Biology, 页码:103-119 , 文章类型: Article,,卷期:2010年403-1]
- The feline immunodeficiency virus (FIV) is a lentivirus that is related to human immunodeficiency virus (HIV), causing a similar pathology in cats. It is a potential small animal model for AIDS and the FIV-based vectors ...
- Expression-System-Dependent Modulation of HIV-1 Envelope Glycoprotein Antigenicity and Immunogenicity
[作者:Kong, L; Sheppard, NC; Stewart-Jones, GBE; Robson, CL; Chen, HY; Xu, XD; Krashias, G; Bonomelli, C; Scanlan, CN; Kwong, PD; Jeffs, SA; Jones, IM; Sattentau, QJ,期刊:Journal of Molecular Biology, 页码:131-147 , 文章类型: Article,,卷期:2010年403-1]
- Recombinant expression systems differ in the type of glycosylation they impart on expressed antigens such as the human immunodeficiency virus type 1 (HIV-1) envelope glycoproteins, potentially affecting their biological ...
- Structure of a Longitudinal Actin Dimer Assembled by Tandem W Domains: Implications for Actin Filament Nucleation
[作者:Rebowski, G; Namgoong, S; Boczkowska, M; Leavis, PC; Navaza, J; Dominguez, R,期刊:Journal of Molecular Biology, 页码:11-23 , 文章类型: Article,,卷期:2010年403-1]
- Actin filament nucleators initiate polymerization in cells in a regulated manner. A common architecture among these molecules consists of tandem WASP homology 2 domains (W domains) that recruit three to four actin subuni...
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