- Structural Determinants of the Multifunctional Profile of Dual Binding Site Acetylcholinesterase Inhibitors as Anti-Alzheimer Agents
[作者:Galdeano, C; Viayna, E; Arroyo, P; Bidon-Chanal, A; Blas, JR; Munoz-Torrero, D; Luque, FJ,期刊:Current Pharmaceutical Design, 页码:2818-2836 , 文章类型: Review,,卷期:2010年16-25]
- Dual binding site acetylcholinesterase inhibitors have recently emerged as a new class of anti-Alzheimer agents with potential to positively modify the course of the disease. These compounds exhibit a multifunctional pha...
- Cell Death Targets and Potential Modulators in Alzheimer's Disease
[作者:Castro, RE; Santos, MMM; Gloria, PMC; Ribeiro, CJA; Ferreira, DMS; Xavier, JM; Moreira, R; Rodrigues, CMP,期刊:Current Pharmaceutical Design, 页码:2851-2864 , 文章类型: Review,,卷期:2010年16-25]
- Apoptosis is now recognized as a normal feature in the development of the nervous system and may also play a role in neurodegenerative disorders, such as Alzheimer's disease. Cell surface receptors, caspases, mitochondri...
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